Results 11 to 20 of about 9,828,326 (308)

Designing a vaccine for tuberculosis [PDF]

open access: yesBMJ, 1996
Tuberculosis is a disease of superlatives. Mycobacterium tuberculosis causes more deaths annually than any other infectious agent.1 Globally, it is one of the major pathogens associated with HIV disease.1 The tuberculosis vaccine, BCG, has been given to more people than any other vaccine.2 3 However, although this vaccine confers clear benefit against ...
A S, Malin, D B, Young
openaire   +2 more sources

Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus

open access: yes, 2021
Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide.
조상래
core   +1 more source

An Immunoinformatics Approach to Design a Potent Multi-Epitope Vaccine against Asia-1 Genotype of Crimean–Congo Haemorrhagic Fever Virus Using the Structural Glycoproteins as a Target

open access: yesVaccines, 2022
Crimean–Congo haemorrhagic fever (CCHF), caused by Crimean–Congo haemorrhagic fever virus (CCHFV), is a disease of worldwide importance (endemic yet not limited to Asia, Middle East, and Africa) and has triggered several outbreaks amounting to a case ...
Syed Zawar Shah   +12 more
doaj   +1 more source

Effectiveness and safety of injectable human papilloma virus vaccine administered as eyedrops

open access: yes, 2023
Mucosal vaccines have the advantages of ease of administration and the induction of strong mucosal immunity and a systemic immune response. Recently, the eye mucosa has been shown to be an effective and safe alternative vaccination route against ...
윤상철, 서경률, 이지혜
core   +1 more source

Computational Design of a Chimeric Vaccine against Plesiomonas shigelloides Using Pan-Genome and Reverse Vaccinology

open access: yes, 2022
The swift emergence of antibiotic resistance (AR) in bacterial pathogens to make themselves adaptable to changing environments has become an alarming health issue. To prevent AR infection, many ways can be accomplished such as by decreasing the misuse of
Hassan, Muhammad   +17 more
core   +1 more source

The rational design of vaccines

open access: yesDrug Discovery Today, 2005
This review provides an insight into the various opportunities for vaccine intervention, analysis of strategies for vaccine development, vaccine ability to modulate immune responses and resultant rational vaccine design. In addition, wider aspects are considered, such as biotechnological advances, advances in immunological understanding and host ...
Bramwell, Vincent W., Perrie, Yvonne
openaire   +2 more sources

Vaccine Design: An Introduction

open access: yes, 2023
Vaccines are the most successful and cost-effective medical interventions available to fight infectious diseases. They consist of biological preparations that are capable of stimulating the immune system to confer protective immunity against a particular harmful pathogen/agent. Vaccine design and development have evolved through the years.
Fiyouzi, Tara, Reche, Pedro A
openaire   +3 more sources

Method to identify efficiently cleaved, membrane-bound, functional HIV-1 (Human Immunodeficiency Virus-1) envelopes

open access: yesMethodsX, 2019
An ideal vaccine against HIV-1 will specifically elicit bNAbs (broadly neutralizing antibodies) which can cross-neutralize a wide spectrum of circulating viral strains belonging to different clades.
Sweety Samal   +2 more
doaj   +1 more source

An In-Silico Investigation to Design a Multi-Epitopes Vaccine against Multi-Drug Resistant Hafnia alvei

open access: yes, 2022
Antimicrobial resistance has become a significant health issue because of the misuse of antibiotics in our daily lives, resulting in high rates of morbidity and mortality.
Alrasheedi, Sahar Falah   +11 more
core   +1 more source

The marginal willingness-to-pay for attributes of a hypothetical HIV vaccine [PDF]

open access: yes, 2012
This paper estimates the marginal willingness-to-pay for attributes of a hypothetical HIV vaccine using discrete choice modeling. We use primary data from 326 respondents from Bangkok and Chiang Mai, Thailand, in 2008–2009, selected using purposive ...
Newman, Peter A.   +15 more
core   +1 more source

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