Results 221 to 230 of about 471,998 (303)

Robust Bioconjugated Antigens Induce Immune Responses Preventing Malaria Infection and its Transmission

Small, EarlyView.
Engineered malaria antigens enable in vivo bioconjugation to submicron biopolymer particles in E. coli. Two antigens are co‐tethered at high density and defined stoichiometry. The resulting thermostable particles elicit strong, durable antibody and T‐cell responses, conferring robust protection and blocking mosquito transmission.
Nivethika Sivakumaran, Yevel Flores‐Garcia, Chanel M. Naar, Shuxiong Chen, Mili Mehta, Fijs W. B. van Leeuwen, Abhai Tripathi, Rajagopal Murugan, Meta Roestenberg, Fidel Zavala, Bernd H. A. Rehm   +10 more
wiley   +1 more source

Evaluation of the Effect of the Mycoplasma hyopneumoniae Live Vaccine (Strain 168) in Ningxiang Pigs. [PDF]

Vaccines (Basel)
Qin Z, Zhao P, Chen L, Han Z, Zhang Y, Zhao J.   +5 more
europepmc   +1 more source

Extrahepatic Gene Editing In Vivo Using Organic Solvent‐Free Lipid Nanoparticles

Small, EarlyView.
This article highlights a novel, organic solvent‐free lipid nanoparticle (LNP) formulation that avoids cholesterol, thereby reducing hepatic accumulation and immune activation. These BLNPs enable potent, flexible, and scalable gene delivery, supporting personalized medicine and diverse nucleic acid applications.
Michael Streiber, Na Liu, Laurianne Simon, Franziska Adermann, Vivien Bachmann, Lucas Gath, Stephanie Hoeppener, Stephanie Schubert, Oliver Werz, Vincent Lapinte, Marie Morille, Michael Bauer, Adrian T. Press, Ulrich S. Schubert, Anja Traeger   +14 more
wiley   +1 more source

Shaping Function: Polymeric 3D Systems With Unconventional Geometries for Biomedical Applications

Small, EarlyView.
Particle shape is a key design parameter governing biological interactions. Advances in fabrication enable precise control over anisotropy and compartmentalization, allowing modulation of cellular uptake, transport, and biodistribution, ultimately enhancing therapeutic performance. ABSTRACT Polymer geometry is a primary determinant of physical behavior
Francisca G. Perfeito, Mariana B. Oliveira, João F. Mano   +2 more
wiley   +1 more source

A Model H5N2 Vaccine Strain for Dual Protection Against H5N1 and H9N2 Avian Influenza Viruses. [PDF]

Vaccines (Basel)
Song JH, Son SE, Kim HW, An SH, Lee CY, Kwon HJ, Choi KS.   +6 more
europepmc   +1 more source

SERS‐Based Nano‐ and Microsystems Toward Biomedical Applications

Small, EarlyView.
This review provides a current overview of nano‐ and microscale SERS‐based devices, encompassing all aspects from material design to practical applications. We highlight controlled SERS‐active architectures, including patterned substrates, nanorods, microspheres, micromotors, and microneedles, as well as combinations of these microfluidic systems.
Gohar Soufi, Tijana Maric, Isidro Badillo‐Ramírez, Juliane Fjelrad Christfort, Matteo Tollemeto, Carmen Milan Guimera, Casper Nisula, Giulia Zappalá, Laura De Vittorio, Marta Rubio‐Huertas, Sungyeong Kim, Ziqiao Li, Morten Bo Søndergaard Svendsen, Zhongyang Zhang, Anja Boisen   +14 more
wiley   +1 more source

Complete genome sequence of a Bangladesh-developed live-attenuated lumpy skin disease (LSD) vaccine strain. [PDF]

Microbiol Resour Announc
Samad MA, Hossen A, Karim MR, Uddin AA, Roy D, Shithi KN, Akter MN, Das TK, Selleck P, Bulach DM, Bowden TR.   +10 more
europepmc   +1 more source

Improvement of the rinderpest vaccine thermostability : End of year 1 and 2 report [PDF]

, 1989
Calvez, D., Diallo, Adama, Lefèvre, Pierre-Charles   +2 more
core  

Assessment of sampling variation applets during development

Teaching Statistics, EarlyView.
Abstract Concepts relating to sampling variation are known to be difficult for learners in introductory classes. There is some evidence that web‐based visualization tools, or “applets,” may aid the learning of these challenging ideas. Four freely available applets developed at the authors' institution were extensively tested through sessions involving ...
Bruce Dunham, Nancy Heckman, Melissa Lee, Mike Whitlock, Gaitri Yapa   +4 more
wiley   +1 more source