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Gut, 2021 Objective Delayed second dose SARS-CoV-2 vaccination trades maximal effectiveness for a lower level of immunity across more of the population. We investigated whether patients with inflammatory bowel disease treated with infliximab have attenuated ...
Nicholas A. Kennedy +2 more
exaly +2 more sources
Generation of DelNS1 Influenza Viruses: a Strategy for Optimizing Live Attenuated Influenza Vaccines
mBio, 2019 Nonstructural protein 1 (NS1) of influenza virus is a key virulence element with multifunctional roles in virus replication and a potent antagonist of host immune response.
Pui Wang +17 more
doaj +2 more sources
SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters
Nature, 2022 The recent emergence of B.1.1.529, the Omicron variant1,2, has raised concerns of escape from protection by vaccines and therapeutic antibodies. A key test for potential countermeasures against B.1.1.529 is their activity in preclinical rodent models of ...
Peter J Halfmann +2 more
exaly +2 more sources
Natural Attenuated Vaccines for Pasteurella multocida [PDF]
BiologyPasteurella multocida is capable of infecting various animal species, causing hemorrhagic septicemia or infectious pneumonia, and it is widely prevalent and pathogenic worldwide.
Qingyuan Xu +3 more
doaj +2 more sources
Frontiers in Immunology, 2014 Despite intense efforts there is no safe and efficacious vaccine against visceral leishmaniasis, which is fatal and endemic in many tropical countries. A major shortcoming in the vaccine development against blood borne parasitic agents such as Leishmania
Sreenivas eGannavaram +5 more
doaj +2 more sources
Research Progress in the Development of Vaccines Against Riemerella anatipestifer [PDF]
MicroorganismsRiemerella anatipestifer (R. anatipestifer, RA) is a globally distributed pathogen responsible for duck serositis, an acute multisystemic disease whose infection leads to substantial economic impacts in duck production.
Junxvan Lan +9 more
doaj +2 more sources
Quality control procedure for Coccidial vaccines versus different routes of immunization [PDF]
Veterinary World, 2022 Background and Aim: Coccidiosis is an enteric infection caused by a protozoon (Eimeria tenella). Coccidiosis is known to have a negative impact on the economy. Coccidiosis is controlled using anticoccidial drugs, antibiotics, and vaccines.
Arwa Elnaggar, Hala Mahmoud, Sahar Saber
doaj +1 more source
Evaluate Risk Analysis of Measurement Uncertainty (MU) of Different Methods Applied for Veterinary Vaccines Evaluation [PDF]
Journal of Applied Veterinary Sciences, 2022 Veterinary Serum and Vaccine Research Institute (VSVRI ) objected to producing highly efficient vaccines from reference or local isolates according to the international specifications for protecting animals and poultry against different diseases and ...
Hala Elsawy +5 more
doaj +1 more source
Genetic stabilization of attenuated oral vaccines against poliovirus types 1 and 3
Nature, 2023 Mouse experiments and deep sequencing confirmed that two additional live attenuated vaccine candidates against type 1 and 3 polioviruses remained attenuated and preserved all documented nOPV2 characteristics concerning genetic stability following ...
Ming-Te Yeh +7 more
semanticscholar +1 more source
Comparative Evaluation of Lumpy Skin Disease Virus-Based Live Attenuated Vaccines
Vaccines, 2021 Vaccines form the cornerstone of any control, eradication and preventative strategy and this is no different for lumpy skin disease. However, the usefulness of a vaccine is determined by a multiplicity of factors which include stability, efficiency ...
A. Haegeman +8 more
semanticscholar +1 more source