MicroRNA-Attenuated Virus Vaccines [PDF]
Live-attenuated vaccines are the most effective way to establish robust, long-lasting immunity against viruses. However, the possibility of reversion to wild type replication and pathogenicity raises concerns over the safety of these vaccines. The use of
Elizabeth J. Fay, Ryan A. Langlois
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Genetically attenuated malaria parasites as vaccines [PDF]
Despite the significant gains made with control efforts, malaria continues to be a dominant infectious disease threat in many parts of the world [1].
Ashley M. Vaughan, Stefan H. I. Kappe
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Research Progress on Varicella-Zoster Virus Vaccines [PDF]
Varicella-zoster virus (VZV) poses significant public health challenges as the etiological agent of varicella (chickenpox) and herpes zoster (HZ), given its high transmissibility and potential for severe complications.
Hongjing Liu+11 more
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Optimal immunization strategies for Saanen goats against goatpox [PDF]
Background Goatpox is a highly contagious disease caused by the Capripoxvirus, primarily affecting sheep and goats. Breeds like the Saanen are particularly vulnerable, especially in enzootic areas, and face risks not only from the disease itself but also
Hossein Esmaeili+6 more
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Single cell transcriptomics correlate avian coronavirus prime vaccination efficacy with antigen-presenting cell preference [PDF]
Biosafe and effective vaccines are urgently needed for the prevention and control of avian infectious bronchitis virus (IBV), the first coronavirus to be discovered, despite extensive vaccination for decades.
Xuefeng Li+12 more
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Quality control procedure for Coccidial vaccines versus different routes of immunization [PDF]
Background and Aim: Coccidiosis is an enteric infection caused by a protozoon (Eimeria tenella). Coccidiosis is known to have a negative impact on the economy. Coccidiosis is controlled using anticoccidial drugs, antibiotics, and vaccines.
Arwa Elnaggar, Hala Mahmoud, Sahar Saber
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Different Types of Vaccines against Pestiviral Infections: “Barriers” for “Pestis”
The genus Pestivirus of the family Flaviviridae mainly comprises classical swine fever virus (CSFV), bovine viral diarrhea virus 1 (BVDV-1), BVDV-2, border disease virus (BDV), and multiple new pestivirus species such as atypical porcine pestivirus (APPV)
Mengqi Yuan+6 more
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Evaluate Risk Analysis of Measurement Uncertainty (MU) of Different Methods Applied for Veterinary Vaccines Evaluation [PDF]
Veterinary Serum and Vaccine Research Institute (VSVRI ) objected to producing highly efficient vaccines from reference or local isolates according to the international specifications for protecting animals and poultry against different diseases and ...
Hala Elsawy+5 more
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Perspectives of Next-Generation Live-Attenuated Rift Valley Fever Vaccines for Animal and Human Use
Live-attenuated Rift Valley fever (RVF) vaccines transiently replicate in the vaccinated host, thereby effectively initiating an innate and adaptive immune response.
Paul J. Wichgers Schreur+4 more
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Rational Design of Live-Attenuated Vaccines against Herpes Simplex Viruses
Diseases caused by human herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) affect millions of people worldwide and range from fatal encephalitis in neonates and herpes keratitis to orofacial and genital herpes, among other manifestations.
Brent A. Stanfield+3 more
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