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MicroRNA-Attenuated Virus Vaccines [PDF]

open access: yesNon-Coding RNA, 2018
Live-attenuated vaccines are the most effective way to establish robust, long-lasting immunity against viruses. However, the possibility of reversion to wild type replication and pathogenicity raises concerns over the safety of these vaccines. The use of
Elizabeth J. Fay, Ryan A. Langlois
doaj   +4 more sources

Genetically attenuated malaria parasites as vaccines [PDF]

open access: yesExpert Review of Vaccines, 2017
Despite the significant gains made with control efforts, malaria continues to be a dominant infectious disease threat in many parts of the world [1].
Ashley M. Vaughan, Stefan H. I. Kappe
doaj   +4 more sources

Research Progress on Varicella-Zoster Virus Vaccines [PDF]

open access: yesVaccines
Varicella-zoster virus (VZV) poses significant public health challenges as the etiological agent of varicella (chickenpox) and herpes zoster (HZ), given its high transmissibility and potential for severe complications.
Hongjing Liu   +11 more
doaj   +2 more sources

Optimal immunization strategies for Saanen goats against goatpox [PDF]

open access: yesBMC Veterinary Research
Background Goatpox is a highly contagious disease caused by the Capripoxvirus, primarily affecting sheep and goats. Breeds like the Saanen are particularly vulnerable, especially in enzootic areas, and face risks not only from the disease itself but also
Hossein Esmaeili   +6 more
doaj   +2 more sources

Single cell transcriptomics correlate avian coronavirus prime vaccination efficacy with antigen-presenting cell preference [PDF]

open access: yesnpj Vaccines
Biosafe and effective vaccines are urgently needed for the prevention and control of avian infectious bronchitis virus (IBV), the first coronavirus to be discovered, despite extensive vaccination for decades.
Xuefeng Li   +12 more
doaj   +2 more sources

Quality control procedure for Coccidial vaccines versus different routes of immunization [PDF]

open access: yesVeterinary World, 2022
Background and Aim: Coccidiosis is an enteric infection caused by a protozoon (Eimeria tenella). Coccidiosis is known to have a negative impact on the economy. Coccidiosis is controlled using anticoccidial drugs, antibiotics, and vaccines.
Arwa Elnaggar, Hala Mahmoud, Sahar Saber
doaj   +1 more source

Different Types of Vaccines against Pestiviral Infections: “Barriers” for “Pestis

open access: yesViruses, 2022
The genus Pestivirus of the family Flaviviridae mainly comprises classical swine fever virus (CSFV), bovine viral diarrhea virus 1 (BVDV-1), BVDV-2, border disease virus (BDV), and multiple new pestivirus species such as atypical porcine pestivirus (APPV)
Mengqi Yuan   +6 more
doaj   +1 more source

Evaluate Risk Analysis of Measurement Uncertainty (MU) of Different Methods Applied for Veterinary Vaccines Evaluation [PDF]

open access: yesJournal of Applied Veterinary Sciences, 2022
Veterinary Serum and Vaccine Research Institute (VSVRI ) objected to producing highly efficient vaccines from reference or local isolates according to the international specifications for protecting animals and poultry against different diseases and ...
Hala Elsawy   +5 more
doaj   +1 more source

Perspectives of Next-Generation Live-Attenuated Rift Valley Fever Vaccines for Animal and Human Use

open access: yesVaccines, 2023
Live-attenuated Rift Valley fever (RVF) vaccines transiently replicate in the vaccinated host, thereby effectively initiating an innate and adaptive immune response.
Paul J. Wichgers Schreur   +4 more
doaj   +1 more source

Rational Design of Live-Attenuated Vaccines against Herpes Simplex Viruses

open access: yesViruses, 2021
Diseases caused by human herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) affect millions of people worldwide and range from fatal encephalitis in neonates and herpes keratitis to orofacial and genital herpes, among other manifestations.
Brent A. Stanfield   +3 more
doaj   +1 more source

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