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Carbohydrate—protein conjugate vaccines [PDF]

open access: yesClinical Microbiology and Infection, 2003
Various pathogenic bacteria have coats of polysaccharide, many with repeating epitopes. Though polysaccharide vaccines have been available for some time, they induce mainly IgM production, and are only moderately protective in adults and ineffective in ...
Ada, G., Isaacs, D.
core   +5 more sources

Current Scientific Advances in Vaccines Against UTIs: Challenges and Prospects [PDF]

open access: yesMicroorganisms
Urinary Tract Infection (UTI), the second most common infectious disease globally, poses a particularly significant threat to adult female populations. Epidemiological data show that Uropathogenic Escherichia coli (UPEC) is responsible for approximately ...
Baoying Wang   +8 more
doaj   +2 more sources

Vaccines against Meningococcal Diseases

open access: yesMicroorganisms, 2020
Neisseria meningitidis is the main cause of meningitis and sepsis, potentially life-threatening conditions. Thanks to advancements in vaccine development, vaccines are now available for five out of six meningococcal disease-causing serogroups (A, B, C, W,
Mariagrazia Pizza   +2 more
doaj   +2 more sources

Evaluation of the Induction of Immune Memory following Infant Immunisation with Serogroup C Neisseria meningitidis Conjugate Vaccines - Exploratory Analyses within a Randomised Controlled Trial [PDF]

open access: yes, 2014
Aim: We measured meningococcal serogroup C (MenC)-specific memory B-cell responses in infants by Enzyme-Linked Immunospot (ELISpot) following different MenC conjugate vaccine schedules to investigate the impact of priming on immune memory.
Birks, Jacqueline   +7 more
core   +20 more sources

Infant protection from invasive Haemophilus influenzae type b disease using the PRP-OMPC conjugate vaccine: An update [PDF]

open access: yesHuman Vaccines & Immunotherapeutics
Invasive disease caused by Haemophilus influenzae type b (Hib) is a major health concern, particularly in children under 5 years of age and vulnerable populations.
Muhamed-Kheir Taha   +5 more
doaj   +2 more sources

Exploring the variables influencing the immune response of traditional and innovative glycoconjugate vaccines

open access: yesFrontiers in Molecular Biosciences, 2023
Vaccines are cost-effective tools for reducing morbidity and mortality caused by infectious diseases. The rapid evolution of pneumococcal conjugate vaccines, the introduction of tetravalent meningococcal conjugate vaccines, mass vaccination campaigns in ...
Francesca Micoli   +4 more
doaj   +1 more source

Vaccine hesitancy and receipt of mandatory and optional pediatric vaccines in Shanghai, China

open access: yesHuman Vaccines & Immunotherapeutics, 2022
Given increased global concern about vaccine hesitancy, this study estimates coverage of mandatory vs non-mandatory vaccines in children, and assesses whether vaccine hesitancy among young parents relates to their childʻs eventual vaccination status in ...
Mengdi Ji   +3 more
doaj   +1 more source

Protein-protein conjugation enhances the immunogenicity of SARS-CoV-2 receptor-binding domain (RBD) vaccines

open access: yesiScience, 2022
Summary: Several effective SARS-CoV-2 vaccines have been developed using different technologies. Although these vaccines target the isolates collected early in the pandemic, many have protected against serious illness from newer variants.
Puthupparampil V. Scaria   +9 more
doaj   +1 more source

A Vaccine Against Group B Streptococcus: Recent Advances [PDF]

open access: yes, 2020
Group B streptococcus (GBS) causes a high burden of neonatal and infant disease globally. Implementing a vaccine for pregnant women is a promising strategy to prevent neonatal and infant GBS disease and has been identified as a priority by the World ...
Carreras-Abad, C   +3 more
core   +2 more sources

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