Results 11 to 20 of about 1,021,347 (190)
Background The epidemiology of acute bacterial meningitis has changed substantially since the introduction of conjugate vaccines. Methods We analyzed nationwide surveillance data of all cerebrospinal fluid isolates received by the Netherlands Reference ...
D. Koelman+5 more
semanticscholar +1 more source
Vaccine hesitancy and receipt of mandatory and optional pediatric vaccines in Shanghai, China
Given increased global concern about vaccine hesitancy, this study estimates coverage of mandatory vs non-mandatory vaccines in children, and assesses whether vaccine hesitancy among young parents relates to their childʻs eventual vaccination status in ...
Mengdi Ji+3 more
doaj +1 more source
Introduction Prior to implementation of Haemophilus influenzae type b (Hib)-conjugate vaccination programs in the 1990s, Hib was the commonest cause of bacterial meningitis in children aged 29,000 deaths worldwide in children aged
M. Slack+6 more
semanticscholar +1 more source
Carbohydrate Conjugates in Vaccine Developments [PDF]
Vaccines are powerful tools that can activate the immune system for protection against various diseases. As carbohydrates can play important roles in immune recognition, they have been widely applied in vaccine development. Carbohydrate antigens have been investigated in vaccines against various pathogenic microbes and cancer.
Shuyao Lang+4 more
openaire +3 more sources
Typhoid fever, an acute febrile illness caused by Salmonella enterica serovar Typhi (S. Typhi), is endemic in many low- and middle-income countries† (1).
Molly Hancuh+10 more
semanticscholar +1 more source
Use of pneumococcal conjugate vaccines (PCVs) has greatly reduced the incidence of invasive pneumococcal disease (IPD). V114 (VAXNEUVANCE™, Merck Sharp & Dohme Corp. a subsidiary of Merck & Co. Inc.
Salini Mohanty+5 more
doaj +1 more source
Facing the availability of the new generation of quadrivalent meningococcal conjugate vaccines (Menveo®, Menactra® and others pending for license) and their recent implementation in Saudi Arabia, experts from 11 countries of the Middle East region met at
Atef Shibl+4 more
doaj +1 more source
Personalized cancer vaccines targeting patient-specific neoantigens are a promising cancer treatment modality; however, neoantigen physicochemical variability can present challenges to manufacturing personalized cancer vaccines in an optimal format for ...
G. Lynn+29 more
semanticscholar +1 more source
Carbohydrate—protein conjugate vaccines [PDF]
Various pathogenic bacteria have coats of polysaccharide, many with repeating epitopes. Though polysaccharide vaccines have been available for some time, they induce mainly IgM production, and are only moderately protective in adults and ineffective in young children.
Ada, Gordon, Isaacs, D
openaire +4 more sources
Promising directions for vaccine development to prevent shigellosis
Shigellosis (bacterial dysentery) is an acute infectious disease caused by Shigella spp., members of the Enterobacteriaceae family. The disease has the highest mortality rate amongst bacterial enteric infections.
M. V. Abramtseva+2 more
doaj +1 more source