Results 161 to 170 of about 274,774 (268)

Next-generation vaccines against bacterial pathogens: mRNA and beyond. [PDF]

Front Immunol
Chen H, Gu Y, Song L, Si L.
europepmc   +1 more source

The generation of tumor vaccines by adenovirus-enhanced transfection of cytokine genes into tumor cells [PDF]

, 1994
Berger, M., Birnstiel, Max L., Buschle, M., Cotten, Matt, Maass, Gerd, Schmidt, Walter, Skouteris, George G., Wagner, Ernst, Zatloukal, Kurt   +8 more
core   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Evaluation of genotype matched recombinant DNA vaccine for protection against genotype VII velogenic Newcastle disease virus in Pakistan. [PDF]

Sci Rep
Razzaq S, Riaz A, Siddique N, Saif-Ur-Rehman, Shah MA, Naeem K, Saleem G.   +6 more
europepmc   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Neoantigens in cancer immunoediting: from mechanisms to personalized vaccines in breast cancer. [PDF]

Front Cell Dev Biol
Zeng S, Wang L, Zeng W, Sun L.
europepmc   +1 more source

Automatically Defining Protein Words for Diverse Functional Predictions Based on Attention Analysis of a Protein Language Model

Advanced Science, EarlyView.
Understanding protein sequence–function relationships remains challenging due to poorly defined motifs and limited residue‐level annotations. An annotation‐agnostic framework is introduced that segments protein sequences into “protein words” using attention patterns from protein language models.
Hedi Chen, Jingrui Zhong, Xiaochun Zhang, Jingke Chen, Lin Guo, Xiaoliang Xiong, Xiaonan Zhang, Xiangyu Liu, Bailong Xiao, Boxue Tian   +9 more
wiley   +1 more source

Systematic analysis of COVID-19 mRNA vaccines using four orthogonal approaches demonstrates no excessive DNA impurities. [PDF]

NPJ Vaccines
Achs A, Sedlackova T, Predajna L, Budis J, Bartosova M, Zelnik V, Rusnakova D, Melichercikova M, Miklosova M, Gencurova V, Cernakova B, Szemes T, Klempa B, Kopacek J, Pastorekova S.   +14 more
europepmc   +1 more source

A Prussian Blue Nanozyme‐Adjuvanted Vaccine Presenting Phosphocholine Antigens for Induction of Immunotolerance in Inflammatory Bowel Disease

Advanced Science, EarlyView.
This study developed a novel nano‐vaccine (Ferritin‐PC@PBNZs) comprising a ferritin‐based scaffold for the multivalent display of phosphorylcholine (PC) antigens, integrated with Prussian blue nanozymes (PBNZs) as a potent adjuvant. By leveraging the ferritin carrier for high‐density and ordered antigen display, the nano‐vaccine significantly augments ...
Jingyi Sheng, Yubo Huang, Xinyue Li, Yin Liu, Yuehuang Wu, Yuxin Zhang, Ning Gu   +6 more
wiley   +1 more source

Cancer Vaccines: Molecular Mechanisms, Clinical Progress, and Combination Immunotherapies with a Focus on Hepatocellular Carcinoma. [PDF]

Curr Issues Mol Biol
Alrumaihi F, Alromaihi RA, Kumar V, Anwar S.   +3 more
europepmc   +1 more source