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Single-Dose Immunogenic DNA Vaccines Coding for Live-Attenuated Alpha- and Flaviviruses [PDF]
VirusesSingle-dose, immunogenic DNA (iDNA) vaccines coding for whole live-attenuated viruses are reviewed. This platform, sometimes called immunization DNA, has been used for vaccine development for flavi- and alphaviruses.
Peter Pushko +3 more
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Journal of Internal Medicine, 2003 Abstract. Liu MA (Strasbourg, France and Karolinska Institute, Stockholm, Sweden). DNA vaccines: a review (Review). J Intern Med 2003; 253: 402–410.The DNA vaccines are simple rings of DNA containing a gene encoding an antigen, and a promoter/terminator to make the gene express in mammalian cells.
Margaret A Liu
exaly +3 more sources
New insights for the development of efficient DNA vaccines [PDF]
Microbial BiotechnologyDespite the great potential of DNA vaccines for a broad range of applications, ranging from prevention of infections, over treatment of autoimmune and allergic diseases to cancer immunotherapies, the implementation of such therapies for clinical ...
Simone Berger +3 more
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The DNA Vaccines for the Gn and Gc Heterologous Polymer of Severe Fever with Thrombocytopenia Syndrome Virus Induce Potent Immunogenicity in Mice [PDF]
VaccinesIntroduction/Background: Severe fever with thrombocytopenia syndrome virus (SFTSV) poses a threat to global public health with a mortality rate of up to 30%. However, there is currently no commercialized SFTSV vaccine.
Qiuju He +8 more
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DNA Vaccines for Epidemic Preparedness: SARS-CoV-2 and Beyond [PDF]
Vaccines, 2023 We highlight the significant progress in developing DNA vaccines during the SARS-CoV-2 pandemic. Specifically, we provide a comprehensive review of the DNA vaccines that have progressed to Phase 2 testing or beyond, including those that have received ...
Joel N. Maslow +8 more
doaj +2 more sources
Japanese Journal of Pharmacology, 2000 DNA vaccination or genetic immunization is a rapidly developing technology that offers new approaches for the prevention and therapy of disease. Regarding the inoculation method of DNA vaccine, we recommend the gene gun delivery system, which is a highly reliable method compared to intramuscular inoculation. DNA vaccines could have potential advantages
Koide, Yukio +3 more
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Brucella abortus RB51 lipopolysaccharide influence as an adjuvant on the therapeutic efficacy of HPV16 L1 and HPV16 E7 DNA vaccines [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Human papillomavirus (HPV) is a primary contributing agent of cervical cancer. Eradication of HPV-related infections requires therapeutic strategies.
Masoumeh Shirmohammadi +4 more
doaj +1 more source
DNA vaccines as promising immuno-therapeutics against cancer: a new insight [PDF]
Frontiers in ImmunologyHamed Afkhami +2 more
exaly +2 more sources
Биопрепараты: Профилактика, диагностика, лечение, 2021 The main triggers of new infectious diseases, including those with pandemic potential, are: spontaneous emergence of infectious strains which are more virulent for humans and contribute to transmission of pathogenic microorganisms, environmental changes,
G. G. Onishchenko +3 more
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