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Current Molecular Medicine, 2001 Within the last decade bacterial plasmids encoding foreign antigens have revolutionized vaccine design. Although no DNA vaccine has yet been approved for routine human or veterinary use, the potential of this vaccine modality has been demonstrated in experimental animal models.
Reyes-Sandoval, A, Ertl, H
core +5 more sources
Vaccines, 2023 The combination of mosaic Gag and CAP256 envelope in an HIV vaccine regimen comprising DNA prime and modified vaccinia Ankara (MVA) boost followed by protein boost has previously been shown to generate robust autologous Tier 2 neutralizing antibodies ...
Rosamund Chapman +5 more
doaj +2 more sources
DNA Vaccines: Their Formulations, Engineering and Delivery. [PDF]
Vaccines (Basel)The concept of DNA vaccination was introduced in the early 1990s. Since then, advancements in the augmentation of the immunogenicity of DNA vaccines have brought this technology to the market, especially in veterinary medicine, to prevent many diseases ...
Kozak M, Hu J.
europepmc +2 more sources
DNA vaccines as promising immuno-therapeutics against cancer: a new insight [PDF]
Frontiers in ImmunologyHamed Afkhami +2 more
exaly +2 more sources
Биопрепараты: Профилактика, диагностика, лечение, 2021 The main triggers of new infectious diseases, including those with pandemic potential, are: spontaneous emergence of infectious strains which are more virulent for humans and contribute to transmission of pathogenic microorganisms, environmental changes,
G. G. Onishchenko +3 more
doaj +1 more source
Analysis of Promising Approaches to COVID-19 Vaccine Development
Биопрепараты: Профилактика, диагностика, лечение, 2020 The number of confirmed COVID-19 cases worldwide amounted to 50 million at the beginning of November 2020. This is clearly not enough for the formation of herd immunity, which will prevent repeated outbreaks of the disease.
G. G. Onishchenko +3 more
doaj +1 more source
Nucleic acid vaccines for human papillomavirus; prevention or treatment [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2019 Introduction: Cervical cancer is the fourth common cancer among women. In almost all cases of this cancer, infection to a high risk human papilloma virus (HPV) especially type 16 and 18 is observed.
Solmaz Moniri Javadhesari +2 more
doaj +1 more source
New vaccines on the horizon [PDF]
Arhiv za farmaciju, 2019 Vaccines are considered to be one of the greatest public health achievements of the last century. As a result of widespread vaccine use, the smallpox virus has been completely eradicated and the incidence of other diseases such as polio, measles, tetanus
Arsenović-Ranin Nevena
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Immunogenicity studies of nucleic acid-based antirabies vaccines in BALB/c mice: A systematic review
BLDE University Journal of Health Sciences, 2023 Improved vaccine efficacy has a major impact on future rabies prevention and control. In this systematic review, a comparative assessment of different nucleic acid-based antirabies vaccination tools developed using different methods, in different ...
Hasanthi Rathnadiwakara +6 more
doaj +1 more source
Nucleic Acid Vaccines: A Rising Antidote for the Future
Journal of Preventive, Diagnostic and Treatment Strategies in Medicine, 2022 DNA vaccines, a type of nucleic acid vaccine, have emerged as one of the recent developments in immunology and recombinant DNA technology, offering great potential in terms of ease of manufacture, maintenance, and safety compared to conventional vaccines.
W. Roseybala Devi +5 more
doaj +1 more source