Results 21 to 30 of about 1,806,959 (282)

Vaccines against toxoplasma gondii : challenges and opportunities [PDF]

open access: yes, 2009
Development of vaccines against Toxoplasma gondii infection in humans is of high priority, given the high burden of disease in some areas of the world like South America, and the lack of effective drugs with few adverse effects.
Jongert, Erik   +4 more
core   +4 more sources

The potential of plant-based vaccines [PDF]

open access: yesFuture Natural Products, 2022
Plants are cost-effective biological delivery carrier. Plant-based vaccines are more reliable due to the lack of human pathogen or endotoxin, and oncogenic DNA.
Mahdi Ghatreh Samani
doaj   +1 more source

Responsiveness to basement membrane extract as a possible trait for tumorigenicity characterization

open access: yesVaccine: X, 2019
Immortalized cell lines used to produce vaccines are expected to be described in terms of their tumorigenicity. However, current in vivo tumorigenicity assays can be time-consuming and results can be equivocal, especially for weakly tumorigenic cells ...
Haruhiko Murata   +7 more
doaj   +1 more source

DENV-3 precursor membrane (prM) glycoprotein enhances E protein immunogenicity and confers protection against DENV-2 infections in a murine model

open access: yesHuman Vaccines & Immunotherapeutics, 2021
To improve a DNA vaccine containing the truncated dengue virus serotype 2 (DENV-2) envelope (E) protein and evaluate the influence of precursor membrane (prM) glycoprotein polymorphism on E protein immunogenicity, two vaccine candidates have been ...
Roberto S. Dias   +7 more
doaj   +1 more source

Immunogenicity studies of nucleic acid-based antirabies vaccines in BALB/c mice: A systematic review

open access: yesBLDE University Journal of Health Sciences, 2023
Improved vaccine efficacy has a major impact on future rabies prevention and control. In this systematic review, a comparative assessment of different nucleic acid-based antirabies vaccination tools developed using different methods, in different ...
Hasanthi Rathnadiwakara   +6 more
doaj   +1 more source

Nucleic Acid Vaccines: A Rising Antidote for the Future

open access: yesJournal of Preventive, Diagnostic and Treatment Strategies in Medicine, 2022
DNA vaccines, a type of nucleic acid vaccine, have emerged as one of the recent developments in immunology and recombinant DNA technology, offering great potential in terms of ease of manufacture, maintenance, and safety compared to conventional vaccines.
W. Roseybala Devi   +5 more
doaj   +1 more source

Genetic (DNA) Vaccines

open access: yesПроблемы особо опасных инфекций, 2010
With the development of various branches of medicine and biology the classical ideas about means to prevent infectious diseases have changed. Nowadays in different countries of the world, investigations are carried out intensively in the sphere of ...
Yu. A. Popov, N. I. Mikshis
doaj   +1 more source

An Overview of DNA Vaccines Development Studies Against Toxoplasma gondii

open access: yesTürkiye Parazitoloji Dergisi, 2022
Toxoplasma gondii (T. gondii) is an obligate intracellular parasite that can infect almost all warm-blooded animals, including humans, and one-third of the global population is thought to be infected with this parasite.
Ceren Gül   +9 more
doaj   +1 more source

A DNA vaccine construct incorporating intercellular trafficking and intracellular targeting motifs effectively primes and induces memory B and T cell responses in outbred animals [PDF]

open access: yes, 2007
We developed a vaccine construct in which a BVP22 domain and an invariant-chain major histocompatibility complex class II-targeting motif capable of enhancing dendritic cell antigen uptake and presentation were fused to a sequence encoding a B- and T ...
Palmer, Guy H   +19 more
core   +1 more source

Vaccination-induced skin-resident memory CD8+ T cells mediate strong protection against cutaneous melanoma

open access: yesOncoImmunology, 2018
Memory CD8+ T cell responses have the potential to mediate long-lasting protection against cancers. Resident memory CD8+ T (Trm) cells stably reside in non-lymphoid tissues and mediate superior innate and adaptive immunity against pathogens.
Felipe Gálvez-Cancino   +13 more
doaj   +1 more source

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