Results 11 to 20 of about 73,565 (199)

Recombinant Protein Vaccines Formulated with Enantio-Specific Cationic Lipid R-DOTAP Induce Protective Cellular and Antibody-Mediated Immune Responses in Mice

Viruses, 2023
Adjuvants are essential components of subunit vaccines added to enhance immune responses to antigens through immunomodulation. Very few adjuvants have been approved for human use by regulatory agencies due to safety concerns.
Siva K. Gandhapudi, Hua Shi, Martin R. Ward, John Peyton Bush, Margarita Avdiushko, Karuna Sundarapandiyan, Lauren V. Wood, Mania Dorrani, Afsheen Fatima, Joe Dervan, Frank Bedu-Addo, Greg Conn, Ted M. Ross, Jerold G. Woodward   +13 more
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Bacterial vaccines in poultry

Bulletin of the National Research Centre, 2020
Background Poultry bacterial pathogens are mainly controlled by using high-cost sanitary measures and medical treatment. However, the drug-resistant strains of pathogens continuously emerge, and medical treatments are often ineffective.
Nagwa S. Rabie, Zeinab M. S. Amin Girh
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Carbohydrate Immune Adjuvants in Subunit Vaccines

Pharmaceutics, 2020
Modern subunit vaccines are composed of antigens and a delivery system and/or adjuvant (immune stimulator) that triggers the desired immune responses.
Sahra Bashiri, Prashamsa Koirala, Istvan Toth, Mariusz Skwarczynski   +3 more
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Evaluation of immunogenicity of gene-deleted and subunit vaccines constructed against the emerging pseudorabies virus variants

Virology Journal, 2023
Background Pseudorabies (PR) (also called Aujeszky’s disease, AD) is a serious infectious disease affecting pigs and other animals worldwide. The emergence of variant strains of pseudorabies virus (PRV) since 2011 has led to PR outbreaks in China and a ...
Hong-liang Zhang, Rui-hua Zhang, Gang Liu, Gui-mei Li, Feng-xue Wang, Yong-jun Wen, Hu Shan   +6 more
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Prospective randomized open-label comparative study of immunogenicity after subunit and polymeric subunit influenza vaccines administration among mothers and infants

Human Vaccines & Immunotherapeutics, 2018
Pregnant women are risk group for influenza infection. Results of new subunit vaccines application have not been studied enough. Prospective, randomized, open-label comparative study of subunit (Agrippal) and polymeric subunit (Grippol plus) vaccines. 42
Mikhail Petrovich Kostinov, Alexander Petrovich Cherdantsev, Alexei Isaevich Kuselman, Nelli Kimovna Akhmatova, Aristitsa Mikhailovna Kostinova, Elena Viktorovna Deryabina, Evgeniia Olegovna Demina, Anton Mikhailovich Kostinov   +7 more
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Effectiveness and Safety of COVID-19 Vaccinations: An Umbrella Meta-Analysis

International Journal of Public Health, 2023
Objectives: This umbrella meta-analysis aims to provide comprehensive and synthesized evidence regarding the effectiveness and safety of COVID-19 vaccinations based on current studies.Methods: Studies from the Cochrane Library, PubMed, and EMBASE ...
Zhu Liduzi Jiesisibieke, Wen-Yi Liu, Wen-Yi Liu, Wen-Yi Liu, Yu-Pei Yang, Ching-Wen Chien, Tao-Hsin Tung   +6 more
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Vaccination is the most effective and best way to avoid the disease of COVID‐19

Immunity, Inflammation and Disease, 2023
Most of the vaccines that are effective against SARS‐CoV‐2 have used the following functional strategies: inactivated viruses, live attenuated viruses, viral vector‐based vaccines, subunit vaccines, recombinant proteins, and DNA/RNA vaccines.
Hadi Lotfi, Mina G. Mazar, Negar M. H. Ei, Mostafa Fahim, Nafiseh S. Yazdi   +4 more
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Re-burying Artificially Exposed Surface of Viral Subunit Vaccines Through Oligomerization Enhances Vaccine Efficacy

Frontiers in Cellular and Infection Microbiology, 2022
Viral subunit vaccines often suffer low efficacy. We recently showed that when taken out of the context of whole virus particles, recombinant subunit vaccines contain artificially exposed surface regions that are non-neutralizing and reduce their ...
Xuelian Han, Zhuming Cai, Yulong Dai, He Huang, Xiangwen Cao, Xiangwen Cao, Yuan Wang, Yingying Fang, Yingying Fang, Gang Liu, Min Zhang, Yuhang Zhang, Binhui Yang, Wei Xue, Guangyu Zhao, Guangyu Zhao, Wanbo Tai, Min Li   +17 more
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African Swine Fever Vaccinology: The Biological Challenges from Immunological Perspectives

Viruses, 2022
African swine fever virus (ASFV), a nucleocytoplasmic large DNA virus (NCLDV), causes African swine fever (ASF), an acute hemorrhagic disease with mortality rates up to 100% in domestic pigs.
James J. Zhu
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Advances in protein subunit vaccines against H1N1/09 influenza

Frontiers in Immunology
The A/H1N1pdm09 influenza virus, which caused the 2009 pandemic, has since become a recurring strain in seasonal influenza outbreaks. Given the ongoing threat of influenza, protein subunit vaccines have garnered significant attention for their safety and
Yu Zhang, Yu Zhang, Jingyao Gao, Wenqi Xu, Xingyu Huo, Jingyan Wang, Yirui Xu, Wenting Ding, Zeliang Guo, Rongzeng Liu   +9 more
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