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Advances and Challenges in Vaccine Development for West Nile Virus (WNV) Infection. [PDF]

open access: yesVaccines (Basel)
Gupta A   +6 more
europepmc   +1 more source
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Rotavirus subunit vaccines

1996
We evaluated rotavirus subunit vaccines for use in humans and animals. Insect cells were co-infected with combinations of individual baculovirus recombinants expressing human, bovine or simian rotavirus VP2, VP4, VP6 or VP7 to produce virus-like particles (VLPs).
Conner, M.E.   +9 more
openaire   +3 more sources

Recombinant subunit vaccines

Current Opinion in Biotechnology, 1991
Research that may lead to the development of recombinant DNA-based vaccines has been conducted on a broad front. This has resulted in an increased understanding of immunological responsiveness to vaccines, the rational engineering of immunogens, and new means of delivering vaccines.
openaire   +2 more sources

Pulmonary Administration of Subunit Vaccines

2014
Pulmonary administration of vaccines might overcome some of the disadvantages related to administration by needle. The lungs are equipped with various immune cells through which a systemic as well as a mucosal immune response can be induced. Different types of devices and formulations can be used to administer vaccines to the lungs, each with their own
Tonnis, Wouter F.   +3 more
openaire   +2 more sources

The herpes zoster subunit vaccine

Expert Opinion on Biological Therapy, 2016
Herpes zoster (HZ) causes severe pain and rash in older people and may be complicated by prolonged pain (postherpetic neuralgia; PHN).HZ results from reactivation of latent varicella-zoster virus (VZV) infection, often associated with age related or other causes of decreased T cell immunity.
openaire   +2 more sources

EFFECTIVE PROTECTION AGAINST INFLUENZA AFTER VACCINATION WITH SUBUNIT VACCINE

Medical Journal of Australia, 1978
Immunization with an influenza subunit vaccine given in one dose about 1 month to 2 months before onset of an epidemic of influenza afforded from 80% to 90% protection in a double-blind clinical trial which was supported by isolation of virus and serological studies. In the vaccinated group, 20% failed to develop antibodies to the vaccine.
M L, Hammond   +3 more
openaire   +2 more sources

Adjuvants and Subunit Vaccines

2010
1 Adjuvants 2 Subunit Vaccines 3 Acknowledgments Keywords: adjuvants and subunit vaccines; immunological phenomena-triggered by vaccine adjuvants; antigen-presenting cells (APC)-activation and expansion of antigen-specific T- and B-cell populations.; new vaccine adjuvants; adjuvants licensed for use in humans, MF59; bacterial ...
Giuseppe Del Giudice, Rino Rappuoli
openaire   +1 more source

[Polysaccharide subunit vaccines].

La Revue du praticien, 1995
The polysaccharide capsules of many germs (pneumococcus, meningococcus, Haemophilus b, salmonella, etc.) can induce synthesis of protective antibodies in man. The development of many vaccines has been based on this phenomenon. Unfortunately, the polysaccharide antigens cannot trigger an immune response before the age of 2 years.
openaire   +1 more source

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