Results 191 to 200 of about 31,151 (261)

Human Papillomavirus: Update in Bridging Basic Science to Clinical and Public Health Innovations

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Human papillomavirus (HPV), a non‐enveloped, double‐strand DNA viral pathogen, is intricately linked with the onset of various cancers, including cervical cancer and head and neck cancers. The present paper delves into HPV's ancient recognition and significant milestones such as the discovery of its role in oncogenesis and the development of ...
Fatemeh Beygnejad, Narges Eslami, Kaveh Gharaei Nejad, Atefeh Zamani Kermanshahi, Hossein Bannazadeh Baghi   +4 more
wiley   +1 more source

Engineering strategies and decision frameworks for virus-like particle-based vaccines against infectious diseases. [PDF]

Front Microbiol
Liu Y, Zhang Y, Liang L, Zhang H, Zhang T, Rong X, Tan J, Mi Y.   +7 more
europepmc   +1 more source

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

iNew Medicine, Volume 2, Issue 2, June 2026.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng, Qianqian Wang, Jiachen Zhang, Sandra Chiu   +3 more
wiley   +1 more source

Maturation-deficient chikungunya virus elicits protective immune responses in a murine challenge model. [PDF]

NPJ Vaccines
Esposito DLA, Guimarães JB, Fonseca BALD, Kümmerer BM.   +3 more
europepmc   +1 more source

Media‐dependent performance of rabies virus‐like particle production under low oxygen tension in baculovirus‐infected Sf9 cells

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 6, Page 1273-1282, June 2026.
Abstract BACKGROUND Rabies continues to pose a major public health threat, causing approximately 59 000 deaths each year, especially in regions with limited resources where high costs restrict vaccine access. Safer and scalable vaccine platforms, such as virus‐like particles, are promising alternatives, but their production is highly sensitive to ...
Júlia Públio Rabello, Milena Miyu Teruya, Fernanda Angela Correia Barrence, Thaissa Consoni Bernardino, Jaci Leme, Luis Giovani de Oliveira Guardalini, Noemi Nosomi Taniwaki, Soraia Attie Calil Jorge, Eutimio Gustavo Fernández Núñez   +8 more
wiley   +1 more source

Preimmunization of SPF Mice With Capsid Virus-like Particle Has no Effect on CD8⁺ Immune Memory and Skin Inflammation in an Ovalbumin-Induced Dermatitis Model. [PDF]

Clin Transl Sci
Kern KS, Henriksen IW, Goksøyr L, Bertelsen AFS, Bartholdy C, Koch J, Hansen CHF, Hansen AK.   +7 more
europepmc   +1 more source

Therapeutic Poxviruses Induce the Secretion of Immunostimulating and Anti‐Tumoral Extracellular Vesicles

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
Immune cells infected by therapeutic poxviruses release increased amounts of extracellular vesicles bearing viral proteins and therapeutic payloads. Such EVs have the ability to activate a CD8+ T‐cell mediated antitumoral immune response and decrease tumor growth.
Lucas Walther, Vincent Mittelheisser, Marie‐Christine Claudepierre, Louis Bochler, Magali Rompais, Jules Deforges, Nathalie Silvestre, Annabel Larnicol, Christine Carapito, Eric Quémeneur, Jacky G Goetz, Karola Rittner, Vincent Hyenne   +12 more
wiley   +1 more source

Next-generation intranasal influenza vaccines: mechanisms, platforms, and translational progress. [PDF]

Front Immunol
Reis LR, Ross TM.
europepmc   +1 more source

Enterococcus faecalis Extracellular Vesicles Deliver the Bacterial GTPase Obg to Hijack mTOR Signalling in Hepatocellular Carcinoma

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
E. faecalis is enriched in HCC tissue and can promote liver tumourigenesis by activating mTOR signalling pathway. Obg derived from E. faecalis extracellular vesicles (EVs) is a GTPase physically interacts with mTOR, and acts as an interkingdom activator of mTOR. EF‐Obg expression level in HCC tissue correlates with poor prognosis in HCC patients.
Ning Ma, Xiaoshan Xie, Jiarui Wang, Zhikai Zheng, Huilin Jin, Xijie Chen, Xiaoling Huang, Haidan Luo, Yue Wei, Qihao Pan, Boyu Zhang, Jiaying Zheng, Peng Zhang, Fenghai Yu, Xue Liu, Zhi‐Min Zhang, Zhongguo Zhou, Xiangqi Meng, Mong‐Hong Lee   +18 more
wiley   +1 more source

Structural insight into the assembly and D antigenicity of polio type 1 stabilized virus-like particles. [PDF]

NPJ Vaccines
Hong Q, Chen T, Han W, Wang S, Lian C, Zhang Y, Ruan L, Wang T, Lin C, Song C, Liu Q, Wang X, Cong Y, Huang Z.   +13 more
europepmc   +1 more source