Results 211 to 220 of about 59,490 (287)

Second Attempt at America First: Donald Trump and the Survival of International Organizations

Global Policy, EarlyView.
ABSTRACT The second Trump administration poses an existential challenge to many international organizations (IOs), putting them at risk of no longer being able to perform their core functions. Compared to the first term, the scope of America First is much wider and the speed much faster.
Hylke Dijkstra
wiley   +1 more source

Major Cat Allergen Fel d 4: Structure and Identification of a Cross‐Reactive IgE‐Epitope‐Containing Area

Allergy, EarlyView.
This study reports the three‐dimensional structure of an important cat allergen, Fel d 4, that shares high homology with Equ c 1 (i.e., major horse allergen) and Can f 6 (i.e., dog allergen). The C‐terminal region of the Fel d 4 contains a major IgE‐reactive epitope.
Nikolina Todorović, Daria Trifonova, Zicheng Liu, Mirela Curin, Laszlo Schooltink, Theo Sagmeister, Christoph Grininger, Renata Kiss, Nina Gottstein, Bernd Gesslbauer, Andreas Winkler, Tea Pavkov‐Keller, Alexander Karaulov, Rudolf Valenta, Walter Keller   +14 more
wiley   +1 more source

Opportunities and Challenges of mRNA and VLP Technologies for Pan-Flavivirus Vaccine Development: Focus on Conserved Quaternary Epitope Conformations. [PDF]

Int J Mol Sci
Pinzon Burgos EF, Camacho Ortega S, Atkinson B, Chua JV, Heredia A.   +4 more
europepmc   +1 more source

Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side

Allergy, EarlyView.
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm, Mohammed Zghaebi, Bita Hambrecht, Tanja Kalic, Christopher C. Udoye, Rudolf Manz, Barbara Bohle, Katarzyna M. Sitnik, Julia Eckl‐Dorna, Heimo Breiteneder   +9 more
wiley   +1 more source

Evaluation of cellular immune response and biosafety of SV40 virus-like particle in tumor immunotherapy. [PDF]

J Mater Sci Mater Med
He T, Hei R, Liu C, Wang H, Gao Z, Dong K, Zhang J.   +6 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Large‐scale reproductive loss in sheep due to Border disease virus infection, New South Wales, Australia

Australian Veterinary Journal, EarlyView.
Border disease viruses (BDV) and bovine viral diarrhoea viruses (BVDV) are members of the Pestivirus genus in the family Flaviviridae. While BVDV is one of the most significant endemic viral infections of cattle in Australia, BDV infection is generally considered to be uncommon in Australian sheep.
K Parrish, ZB Spiers, MS Hazelton, KH Walker, E Duggan, W Graham, DS Finlaison, PD Kirkland   +7 more
wiley   +1 more source

Investigating the impact of oxygen concentration on the assembly of human papillomavirus virus like particles. [PDF]

Sci Rep
Liu Y, Chen D, Gao W, Shen E, Chen X, Du X, Wang D, Zhou S, Zhang H, Yu X, Liu Y.   +10 more
europepmc   +1 more source

Synergistic antiviral activity against human adenovirus through combination of itraconazole and brincidofovir

British Journal of Pharmacology, EarlyView.
Background and Purpose Human adenovirus (HAdV) causes respiratory or gastrointestinal tract infections depending on the virus subtype. While HAdV infections are generally self‐limiting in immunocompetent people, they can result in significant morbidity and mortality in immunocompromised adults and children.
Mohamed Zamzamy, Sophie Post, Wing Hang Ip, Elin Hahlin, Sebastian Kühn, Andrea Pirosu, Christian Conze, Martin Baumdick, Hamburg Intestinal Study Group, Madeleine J. Bunders, Britta F. Zecher, Angelique Hoelzemer, Stephan Linder, Niklas Arnberg, Thomas Dobner, Marcus Altfeld, Sebastian Schloer   +16 more
wiley   +1 more source

Special Issue: "Viruses Associated with Gastroenteritis". [PDF]

Viruses
Cunha C, Istrate C.
europepmc   +1 more source