Results 101 to 110 of about 1,302,625 (339)
Frontiers in Immunology, 2015 Staphylococcus aureus (S. aureus) is an important opportunistic pathogen that may cause invasive life-threatening infections like sepsis and pneumonia. Due to increasing antibiotic-resistance, the development of an effective vaccine against S.
Elisabetta eMonaci +24 more
doaj +1 more source
Advanced Functional Materials, EarlyView.The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar +6 more
wiley +1 more source
Subunit Vaccines Against Emerging Pathogenic Human Coronaviruses
Frontiers in Microbiology, 2020 Seven coronaviruses (CoVs) have been isolated from humans so far. Among them, three emerging pathogenic CoVs, including severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and a newly ...
Ning Wang, J. Shang, Shibo Jiang, L. Du
semanticscholar +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Absolute quantitation of binding antibodies from clinical samples
npj VaccinesThe quantitation of antibody responses is a critical requirement for the successful development of vaccines and therapeutics that often relies on the use of standardized reference materials to determine relative quantities within biological samples.
Chan Tang +17 more
doaj +1 more source
The promise of mRNA vaccines: a biotech and industrial perspective
npj Vaccines, 2020 mRNA technologies have the potential to transform areas of medicine, including the prophylaxis of infectious diseases. The advantages for vaccines range from the acceleration of immunogen discovery to rapid response and multiple disease target ...
Nicholas A. C. Jackson +4 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.A facile and effective method to boost NIR light induced photocatalysis based on nontoxic NIR emissive carbon dots (nir‐CDs) via Self‐trapped excitons, showing that both O2− • and •OH can be generated from nir‐CDs under NIR laser irradiation. Abstract Near‐infrared (NIR) light‐triggered photocatalytic therapy remains a critical challenge in efficient ...
Qingcheng Wang +8 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.The new generation nanobomb, termed the stealth nanobomb, is fabricated through self‐assembly using a polymeric carbon monoxide carrier (PLGA(CO)), small molecule near‐infrared‐active agents (2TT‐OC46B), and phospholipid polyethylene glycol (DSPE‐mPEG2000). The stealth nanobomb can circulate in the bloodstream and specifically target pancreatic cancer,
Gongcheng Ma +10 more
wiley +1 more source
Decision-making for PCV in adults
Human Vaccines & Immunotherapeutics, 2019 Thirteen-valent pneumococcal conjugate vaccine (PCV13) was licensed in adults to address the unmet medical need of vaccine-type community acquired pneumonia (CAP) and the limitations of previous plain-polysaccharide vaccines.
John M. McLaughlin +3 more
doaj +1 more source