Results 101 to 110 of about 1,772,507 (392)
Nature Communications, 2017 Boosting of maternal antibodies against RSV is a potential approach to protect infants from severe infection, but data from animal models is missing. Here Steff et al.
Ann-Muriel Steff +8 more
doaj +1 more source
SARS-CoV-2 vaccines strategies: a comprehensive review of phase 3 candidates
npj Vaccines, 2021 The new SARS-CoV-2 virus is an RNA virus that belongs to the Coronaviridae family and causes COVID-19 disease. The newly sequenced virus appears to originate in China and rapidly spread throughout the world, becoming a pandemic that, until January 5th ...
N. Kyriakidis +4 more
semanticscholar +1 more source
Experience and Challenges from Clinical Trials with Malaria Vaccines in Africa. [PDF]
, 2013 Malaria vaccines are considered amongst the most important modalities for potential elimination of malaria disease and transmission. Research and development in this field has been an area of intense effort by many groups over the last few decades ...
A Nyika +67 more
core +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Managing long COVID in people with multiple sclerosis and related disorders (pwMSRD) is complex due to overlapping symptoms. To address evidence gaps, we evaluated long COVID susceptibility in pwMSRD versus controls and its associations with multi‐domain function and disability.
Chen Hu +15 more
wiley +1 more source
Stabilizing the closed SARS-CoV-2 spike trimer
Nature Communications, 2021 SARS-CoV-2 S protein prematurely refolds to the post-fusion conformation, compromising immunogenic properties and prefusion trimer yield. Here, Juraszek et al.
Jarek Juraszek +8 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini +13 more
wiley +1 more source
Arthritis Care &Research, Accepted Article.Objective We aimed to identify unique disease trajectories within rheumatoid arthritis‐associated interstitial lung disease (RA‐ILD) based on longitudinal forced vital capacity (FVC) values and their associated clinical outcomes. Methods We performed a cohort study of RA‐ILD within the Veterans Health Administration from 1999‐2021. RA‐ILD patients were
Bryant R. England +9 more
wiley +1 more source
To vaccinate or not to vaccinate [PDF]
Schweizerische Ärztezeitung, 2020 Cynthia M. Harley +2 more
openaire +4 more sources
Mechanism of action of mRNA-based vaccines
Expert Review of Vaccines, 2017 Introduction: The present review summarizes the growing body of work defining the mechanisms of action of this exciting new vaccine technology that should allow rational approaches in the design of next generation mRNA vaccines.
Carlo Iavarone +4 more
doaj +1 more source