Results 31 to 40 of about 46,668 (172)

Spherical Nucleic Acid Stabilized Cage Type Three‐Dimensional Electrochemiluminescence Probe for Sensitive and Amplification‐Free Diagnosis of Infectious Diseases

Exploration, EarlyView.
This work developed a spherical nucleic acid stabilized cage‐type 3D electrochemiluminescence reporter probe for amplification‐free and ultrasensitive detection of pathogenic. Furthermore, a hand‐held detection device was designed, and we established a straightforward workflow enabling sample to answer within 15 min.
Yu Fu, Wenlu Song, Jinyan Lin, Wei Wang, Lunjing Liu, Wenjie Wu, Huiyi Yang, Jingru Wang, Yang Yang, Bowen Shu, Yideng Jiang, Yuhui Liao   +11 more
wiley   +1 more source

Genomic identification of human vaccinia virus keratoconjunctivitis and its importance as a laboratory-acquired infection

Indian Journal of Ophthalmology, 2016
Context: Vaccinia virus (VACV) is a member of orthopoxvirus genus of the family Poxviridae. VACVs are enveloped, double-stranded DNA viruses. Several species of this family, for example, molluscum contagiosum, smallpox, deerpox, horsepox, rabbitpox, and ...
Zahra Movahedi Motlagh, Azam Mokhtari, Mohammadreza Mahzounieh   +2 more
doaj   +1 more source

Single Immunization of a Vaccine Vectored by a Novel Recombinant Vaccinia Virus Affords Effective Protection Against Respiratory Syncytial Virus Infection in Cotton Rats

Frontiers in Immunology, 2021
Respiratory syncytial virus (RSV) is a leading cause of respiratory infections worldwide and disease management measures are hampered by the lack of a safe and effective vaccine against the infection.
Marsha S. Russell, Sathya N. Thulasi Raman, Caroline Gravel, Wanyue Zhang, Wanyue Zhang, Annabelle Pfeifle, Annabelle Pfeifle, Wangxue Chen, Gary Van Domselaar, David Safronetz, Michael Johnston, Michael Johnston, Simon Sauve, Lisheng Wang, Michael Rosu-Myles, Michael Rosu-Myles, Jingxin Cao, Xuguang Li, Xuguang Li   +18 more
doaj   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Assessing recombinant vaccinia virus as a delivery system for fertility control vaccines in the brushtail possum (Trichosurus vulpecula)

Julius-Kühn-Archiv, 2011
The introduced brushtail possum (Trichosurus vulpecula) is a major threat to native biodiversity and agricultural production in New Zealand. Research on non-lethal management methods is focussed on fertility control, and aims to develop zona pellucida ...
Duckworth, J., Cross, M., Fleming, S., Scobie, S., Whelan, E., Prada, D., Mercer, A., Cowan, P.   +7 more
doaj   +1 more source

Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa, Birhanetensay Masresha Altaye, Yuh‐Pyng Sher   +2 more
wiley   +1 more source

Vaccinia Virus: Mechanisms Supporting Immune Evasion and Successful Long-Term Protective Immunity

Viruses
Vaccinia virus is the most successful vaccine in human history and functions as a protective vaccine against smallpox and monkeypox, highlighting the importance of ongoing research into vaccinia due to its genetic similarity to other emergent poxviruses.
Joy Hsu, Suyon Kim, Niroshana Anandasabapathy   +2 more
doaj   +1 more source

Recurrent Respiratory Papillomatosis Foundation Position Statement on the Management of Adults With RRP

The Laryngoscope, EarlyView.
ABSTRACT Objective With regulatory approval of HPV‐specific immunotherapy for recurrent respiratory papillomatosis (RRP) and growing experience with systemic bevacizumab, a management algorithm incorporating these medical treatments is warranted. Data Sources and Methods RRP Foundation (RRPF) Key Opinion Leaders offer a proposed management algorithm ...
Simon R. Best, Aaron D. Friedman, Clark A. Rosen, Robert T. Sataloff, Laura A. Matrka, H. Steven Sims, David E. Rosow, Nabil F. Saba, David G. Lott, Adam M. Klein, Ted Mau, Milan R. Amin, Kathryn A. Wikenheiser‐Brokamp, Scott M. Norberg, Kim McClellan, Geoffrey D. Young, Clint T. Allen, on behalf of the Recurrent Respiratory Papillomatosis Foundation   +17 more
wiley   +1 more source

Expression of an Efficient Selection Marker Out of a Duplicated Site in the ITRs of a Modified Vaccinia Virus Ankara (MVA)

Vaccines
Background/Objectives: Poxviruses are large DNA viruses that replicate in the host cytoplasm without a nuclear phase. As vaccine vectors, they can package and express large recombinant cassettes from different positions of their genomic core region.
Sirine Abidi, Aurora Elhazaz Fernandez, Nicole Seehase, Lina Hanisch, Alexander Karlas, Volker Sandig, Ingo Jordan   +6 more
doaj   +1 more source

Relationship between food quality and body size of common vole in different habitats

Pest Management Science, EarlyView.
The body size of the common vole in crop fields (alfalfa, rape, cereals) is larger than in less‐cultivated habitats (forests, clearings, set‐aside) and is not related to food quality. Abstract BACKGROUND There is a close relationship between habitat, food and demographic parameters of common vole populations.
Eva Jánová, Ladislav Čepelka, Josef Suchomel, Marta Heroldová   +3 more
wiley   +1 more source