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Журнал микробиологии, эпидемиологии и иммунобиологииIntroduction. In 2022, the World Health Organization declared monkeypox a public health emergency. The monkeypox virus (MPV) is part of the Orthopoxvirus genus within the Poxviridae family.
Denis I. Zrelkin +12 more
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Outbreak of Severe Zoonotic Vaccinia Virus Infection, Southeastern Brazil
Emerging Infectious Diseases, 2015 In 2010, a vaccinia virus isolate caused an atypically severe outbreak that affected humans and cattle in Brazil. Of 26 rural workers affected, 12 were hospitalized.
Jônatas Santos Abrahão +5 more
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Trained Immunity in Childhood Vaccination
Acta Paediatrica, Volume 115, Issue 11, Page 2402-2413, November 2026.Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai +2 more
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Exploring the Development of Vaccine Platforms, With a Particular Focus on the COVID‐19 Pandemic
Acta Paediatrica, Volume 115, Issue 11, Page 2421-2426, November 2026.ABSTRACT Vaccines have been a cornerstone of human health for more than 200 years and one of the most important tools to reduce childhood deaths caused by pathogens. The concept of vaccines is basically to take something safe, make it immunogenic and induce an immune response in the host that will protect it against something dangerous. Live attenuated
Matti Sällberg
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Clinical signs, diagnosis, and case reports of Vaccinia virus infections
Brazilian Journal of Infectious Diseases, 2010 Vaccinia virus is responsible for a zoonosis that usually affects cattle and human beings in Brazil. The initial clinical signs of the infection are focal red skin areas, fever, and general symptoms similar to those of a cold.
Daniela Carla Medeiros-Silva +4 more
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Effect of p-Fluorophenylalanine on the synthesis of vaccinia virus [PDF]
, 1965 The effect of the amino acid analog FPA on vaccinia virus replication in HeLa cells was investigated. By varying the dose of FPA or the time after infection at which the analog was added to cultures, it was possible to inhibit differentially the ...
Loh, Philip Choo Seng, Payne, Francis E.
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Vaccines, 2019 There are few studies comparing the safety and immunogenicity of the same HIV immunogen in healthy volunteers and HIV-infected individuals. We analyzed demographics, adverse events (AEs), and immunogenicity against vaccinia virus in preventive (RISVAC02,
Elvira Couto +15 more
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Rescue of Synthetic Genomic RNA Analogs of Rabies Virus by Plasmid-Encoded Proteins [PDF]
, 1994 Proteins entirely expressed from cDNA were used to rescue synthetic RNA genome analogs into infectious defective particles of rabies virus (RV). Synthetic negative-stranded RNAs containing 3'- and 5'-terminal RV sequences and transcriptional ...
Schnell, M.-J. +3 more
core
Target cell-dependent T cell-mediated lysis of vaccinia virus-infected cells [PDF]
, 1975 Vaccinia virus specific cytotoxicity against infected target cells was observed in vitro. Spleen lymphocytes from normal and immunized mice of the inbred strains C3H and DBA/2 were incubated with vaccinia virus-infected and non-infected 51Cr-labeled ...
Koszinowski, Ulrich H. +3 more
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Immunisation with Inactive Vaccinia Virus [PDF]
Journal of Hygiene, 1932 Experiments were carried out on rabbits, guinea-pigs and monkeys to test the immunity produced by vaccinia virus killed with heat, phenol or formalin. Before use, the vaccines were rigorously tested for their inactivity by a method of inoculation and triple passage in series.
openaire +2 more sources