Results 81 to 90 of about 44,247 (197)
There are few studies comparing the safety and immunogenicity of the same HIV immunogen in healthy volunteers and HIV-infected individuals. We analyzed demographics, adverse events (AEs), and immunogenicity against vaccinia virus in preventive (RISVAC02,
Elvira Couto +15 more
doaj +1 more source
The Heat Inactivation of Vaccinia Virus [PDF]
SUMMARY: Heat inactivation curves of vaccinia virus between 50° and 60° indicate that the virus is heterogeneous in its heat sensitivity. The proportion of heat-resistant particles varies inversely with the temperature of exposure. The inactivation of heat-sensitive virus is temperature dependent and seems to be a first-order reaction, while the heat ...
openaire +2 more sources
Integrating Oncolytic Virus Engineering and Delivery Strategies for Enhanced Cancer Virotherapy
Integrated engineering strategies combining oncolytic virus (OV) design with advanced delivery platforms overcome biological barriers and enhance cancer virotherapy. Genetic engineering improves viral potency and selectivity, while local and systemic delivery systems promote viral protection, tumor targeting, penetration, and tumor microenvironment ...
Jiliang Zhao +5 more
wiley +1 more source
CENTRIFUGE EXPERIMENTS WITH THE VIRUS OF VACCINIA [PDF]
Centrifuge experiments have been carried out with cell-free, active filtrates of vaccinia virus. The experiments have shown that the virus can be concentrated by this method, even in filtrates which have been subjected to prolonged preliminary centrifugation to throw down any inert particles which may have been present in the original filtrate.
openaire +2 more sources
A scalable purification strategy using hydroxyl (OH) monolithic chromatography enables efficient isolation and direct concentration of MSC‐EVs from adherent and microcarrier‐based upstreams. This approach supports process scale‐up while ensuring high purity suitable for therapeutic EV manufacturing.
Katja Vrabec +8 more
wiley +1 more source
Human Papillomavirus: Update in Bridging Basic Science to Clinical and Public Health Innovations
ABSTRACT Human papillomavirus (HPV), a non‐enveloped, double‐strand DNA viral pathogen, is intricately linked with the onset of various cancers, including cervical cancer and head and neck cancers. The present paper delves into HPV's ancient recognition and significant milestones such as the discovery of its role in oncogenesis and the development of ...
Fatemeh Beygnejad +4 more
wiley +1 more source
ABSTRACT Background and Aims Monkeypox virus (MPXV) is gaining attention in the global health community due to its potential for human transmission and similarities to the well‐known smallpox virus. Mpox was first detected in the 1970s and mostly affects Central and West Africa.
Muslim Bin Aqeel +5 more
wiley +1 more source
Reverse Genetics of Orthoflaviviruses: Strategies for Constructing Functional or Infectious cDNA
ABSTRACT Reverse genetics (RG) systems have transformed RNA virus research by enabling the recovery of recombinant viruses entirely from cloned cDNA. These platforms allow precise, hypothesis‐driven manipulation of viral genomes and support systematic phenotypic analyses in vitro and in vivo.
Young‐Min Lee
wiley +1 more source
Repurposed Medicines for Viruses With Epidemic or Pandemic Potential: A Horizon Scan
ABSTRACT Viruses such as Ebola, Marburg, influenza, mpox, MERS‐CoV, SARS‐CoV, and SARS‐CoV‐2 may be considered pathogens of epidemic or pandemic concern. Developing novel antiviral medicines can be time‐consuming and resource intensive. Repurposing existing medicines with known or potential antiviral activity offers a faster, cost‐effective strategy to
Sola Akinbolade +5 more
wiley +1 more source
Relationship between food quality and body size of common vole in different habitats
The body size of the common vole in crop fields (alfalfa, rape, cereals) is larger than in less‐cultivated habitats (forests, clearings, set‐aside) and is not related to food quality. Abstract BACKGROUND There is a close relationship between habitat, food and demographic parameters of common vole populations.
Eva Jánová +3 more
wiley +1 more source

