There are few studies comparing the safety and immunogenicity of the same HIV immunogen in healthy volunteers and HIV-infected individuals. We analyzed demographics, adverse events (AEs), and immunogenicity against vaccinia virus in preventive (RISVAC02,
Elvira Couto+15 more
doaj +1 more source
Presentation of CMV immediate-early antigen to cytolytic T lymphocytes is selectively prevented by viral genes expressed in the early phase [PDF]
The regulation of antigen processing and presentation to MHC class I-restricted cytolytic T lymphocytes was studied in cells infected with murine cytomegalovirus. Recognition by cytolytic T lymphocytes of the phosphoprotein pp89, the immunodominant viral
Bernards+48 more
core +1 more source
The DC receptor DNGR-1 mediates cross-priming of CTLs during vaccinia virus infection in mice.
In order to prime T cells, DCs integrate signals emanating directly from pathogens and from their noxious action on the host. DNGR-1 (CLEC9A) is a DC-restricted receptor that detects dead cells.
S. Iborra+5 more
semanticscholar +1 more source
Functional domains of the influenza A virus PB2 protein:identification of NP- and PB1-binding sites [PDF]
Influenza virus genomic RNA segments are packaged into ribonucleoprotein (RNP) structures by the PB1, PB2, and PA subunits of an RNA polymerase and a single-strand RNA-binding nucleoprotein (NP).
Digard, Paul+3 more
core +1 more source
Oncolytic virus therapy: A new era of cancer treatment at dawn
Oncolytic virus therapy is perhaps the next major breakthrough in cancer treatment following the success in immunotherapy using immune checkpoint inhibitors.
H. Fukuhara, Y. Ino, T. Todo
semanticscholar +1 more source
mRNA Vaccine Against Mpox: A Promising Healthcare Strategy
Animal Research and One Health, Volume 3, Issue 2, Page 177-180, May 2025.
Mohammad Shah Alam+3 more
wiley +1 more source
Chimeric Yellow Fever/Dengue Virus as a Candidate Dengue Vaccine: Quantitation of the Dengue Virus-Specific CD8 T-Cell Response [PDF]
We have constructed a chimeric yellow fever/dengue (YF/DEN) virus, which expresses the premembrane (prM) and envelope (E) genes from DEN type 2 (DEN-2) virus in a YF virus (YFV-17D) genetic background. Immunization of BALB/c mice with this chimeric virus
Ahmed, Rafi+3 more
core +2 more sources
Immunisation with Inactive Vaccinia Virus [PDF]
Experiments were carried out on rabbits, guinea-pigs and monkeys to test the immunity produced by vaccinia virus killed with heat, phenol or formalin. Before use, the vaccines were rigorously tested for their inactivity by a method of inoculation and triple passage in series.
openaire +3 more sources
Intracellular Development of Vaccinia Virus.
Summary1. Electron micrographs of tissue sections of chorioallantoic membrane infected with vaccinia virus were examined. Some cells were found to be almost filled with virus, others contained the virus particles grouped in single inclusions of varying sizes.
Joseph L. Melnick+2 more
openaire +3 more sources
The liberation of cell-bound vaccinia virus by ultrasonic vibration [PDF]
Ian Macpherson
openalex +1 more source