Results 51 to 60 of about 1,083,137 (225)

In vitro characterization of the antiviral activity of Secomet V against vaccinia virus infections [PDF]

, 2004
Includes bibliographical references (leaves 65-77).The anti-poxvirus agent SECOMET V was the reference name for a plant extract produced in a bioreactor from primary plant stem cells, whose antiviral activity has been widely reported in folklore medicine.
Rangel Lopes de Campos, Walter
core   +1 more source

Buffalopox Disease in Livestock and Milkers, India

Emerging Infectious Diseases, 2021
Buffalopox outbreaks caused by vaccinia virus were observed in villages of Tamil Nadu, India, among lactating buffaloes and cows. Milkers also had lesions on their fingers.
Parimal Roy, Andrew Chandramohan
doaj   +1 more source

Human vaccinia-like virus outbreaks in São Paulo and Goiás States, Brazil: virus detection, isolation and identification Surtos de vírus Vaccinia-like nos Estados de São Paulo e Goiás, Brasil: detecção, isolamento e identificação viral

Revista do Instituto de Medicina Tropical de São Paulo, 2004
Since October 2001, the Adolfo Lutz Institute has been receiving vesicular fluids and scab specimens of patients from Paraíba Valley region in the São Paulo and Minas Gerais States and from São Patricio Valley, in the Goiás State.
Teresa Keico Nagasse-Sugahara, Jonas José Kisielius, Marli Ueda-Ito, Suely Pires Curti, Cristina Adelaide Figueiredo, Áurea Silveira Cruz, Maysa Madalena J. Silva, Carmen Helena Ramos, Maria Claudia C. Silva, Tiyo Sakurai, Luis Florêncio Salles-Gomes   +10 more
doaj   +1 more source

Pietro Verri: The History of Smallpox Vaccination Through His Pencil

JEADV Clinical Practice, EarlyView.
ABSTRACT The last case of natural smallpox infection occurred in 1977, and the disease is considered eradicated since 1980. Throughout the history of medicine, early attempts to combat smallpox involved inoculation, a practice based on the observation that those who recovered from the disease became immune.
Omar Simonetti, Anna Maria Salvadè, Verena Zerbato, Ivo Maria Crosato, Stefano Di Bella, Francesco Bellinato   +5 more
wiley   +1 more source

Induction and in Vitro demonstration of cellular immunity to DNA and RNA viruses in guinea-pigs [PDF]

, 1975
Guinea-pigs were immunized with different cells infected with vaccinia virus, herpes simplex virus type 1, herpesvirus saimiri, and the virus of vesicular stomatitis. Development of cellular immunity against these viruses was observed with transformation
Koszinowski, Ulrich H., Bandlow, G.
core   +1 more source

A Multiple‐Model‐Informed Drug‐Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 572-582, March 2025.
ABSTRACT The antitumor efficacy of an intratumoral injection of a genetically engineered oncolytic vaccinia virus carrying human IL‐7 and murine IL‐12 genes (hIL‐7/mIL‐12‐VV) was demonstrated in CT26.WT‐bearing mice. In the CT26.WT‐bearing mouse model, the efficacy of the combination of hIL‐7/mIL‐12‐VV plus the anti‐programmed cell death protein (PD)‐1
Akihiro Yamada, Mary P. Choules, Frances A. Brightman, Shigeru Takeshita, Shinsuke Nakao, Nobuaki Amino, Takeshi Nakayama, Masato Takeuchi, Kanji Komatsu, Fernando Ortega, Hitesh Mistry, David Orrell, Christophe Chassagnole, Peter L. Bonate   +13 more
wiley   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Vaccinia Scars Associated with Improved Survival among Adults in Rural Guinea-Bissau [PDF]

, 2006
Background: In urban Guinea-Bissau, adults with a vaccinia scar had better survival but also a higher prevalence of HIV-2 infection. We therefore investigated the association between vaccinia scar and survival and HIV infection in a rural area of Guinea ...
Jensen, Mette Lundsby, Leligdowicz Aleksandra, Maarten Schim van der Loeff, Whittle Hilton, Christine Stabell Benn, Dave, S, Aaby, Peter, Lisse Ida Maria, Roth, Adam, Tim Vincent, Aleksandra Leligdowicz, Schimvan der Loeff, M, Schim van der Loeff, Maarten, Carlos da Costa, Dave, Sangeeta, Ravn, Henrik, Dave Sangeeta, Mette Lundsby Jensen, Sangeeta Dave, Jensen Mette Lundsby, Vincent Tim, Leligdowicz, A, Lisse, Ida Maria, Lisse, IM, Ravn, H, Whittle, Hilton, Ida Maria Lisse, Adam Roth, Whittle, H, Roth Adam, Benn Christine Stabell, Roth, A, Aaby Peter, Leligdowicz, Aleksandra, da Costa Carlos, Henrik Ravn, Peter Aaby, Aaby, P, van der Loeff Maarten Schim, Hilton Whittle, Vincent, Tim, Ravn Henrik, da Costa, Carlos, Jensen, ML, da Costa, C, Vincent, T, Benn, CS, Benn, Christine Stabell   +47 more
core   +1 more source

Vaccinia virus transcription

Journal of General Virology, 2003
Vaccinia virus replication takes place in the cytoplasm of the host cell. The nearly 200 kbp genome owes part of its complexity to encoding most of the proteins involved in genome and mRNA synthesis. The multisubunit vaccinia virus RNA polymerase requires a separate set of virus-encoded proteins for the transcription of the early, intermediate and late
openaire   +2 more sources

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source