Results 31 to 40 of about 2,250 (114)

The Yeast Vacuolar Proton-translocating ATPase Contains a Subunit Homologous to the Manduca sexta and Bovine e Subunits That Is Essential for Function [PDF]

Journal of Biological Chemistry, 2004
The yeast cwh36Delta mutant was identified in a screen for yeast mutants exhibiting a Vma(-) phenotype suggestive of loss of vacuolar proton-translocating ATPase (V-ATPase) activity. The mutation disrupts two genes, CWH36 and a recently identified open reading frame on the opposite strand, YCL005W-A.
Maria J. Sambade, Patricia M. Kane
openalex   +4 more sources

Proteomic changes during boron tolerance in barley(Hordeum vulgare) and the role of vacuolar proton-translocating ATPase subunit E

Turkish Journal of Botany, 2011
Boron is an essential micronutrient for plants and animals; however, it can be toxic when present at high concentrations. The purpose of this study was to understand the mechanisms of boron tolerance in the Turkish barley (Hordeum vulgare) Anadolu cultivar.
A. Emin Atik, G. Ozan Bozdag, Ersin AKINCI, Alaattin Kaya, Ahmet Koç, Talat Yalçın, Hüseyin Çağlar Karakaya   +6 more
  +6 more sources

Conformation of a Peptide Encompassing the Proton Translocation Channel of Vacuolar H+-ATPase [PDF]

Biophysical Journal, 2007
The structural properties of a crucial transmembrane helix for proton translocation in vacuolar ATPase are studied using double site-directed spin-labeling combined with electron spin resonance (ESR) (or electron paramagnetic resonance) and circular dichroism spectroscopy in sodium dodecyl sulfate micelles.
Vos, W.L., Vermeer, L.S., Hemminga, M.A.
openaire   +3 more sources

The proton translocation domain of cellular vacuolar ATPase provides a target for the treatment of influenza A virus infections. [PDF]

British journal of pharmacology, 2012
Cellular vacuolar ATPases (v-ATPase) play an important role in endosomal acidification, a critical step in influenza A virus (IAV) host cell infection. We investigated the antiviral activity of the v-ATPase inhibitor saliphenylhalamide (SaliPhe) and compared it with several older v-ATPase inhibitors concanamycin A, bafilomycin A1, (BafA) and archazolid
Konstantin H, Müller, Denis E, Kainov, Karim, El Bakkouri, Xavier, Saelens, Jef K, De Brabander, Christian, Kittel, Elisabeth, Samm, Claude P, Muller   +7 more
openaire   +2 more sources

Interaction of dibutyltin-3-hydroxyflavone bromide with the 16 kDa proteolipid indicates the disposition of proton translocation sites of the vacuolar ATPase [PDF]

Biochemical Journal, 1996
The organotin complex dibutyltin-3-hydroxyflavone bromide [Bu2Sn(of)Br] has been shown to bind to the 16 kDa proteolipid of Nephrops norvegicus, either in the form of the native protein or after heterologous expression in Saccharomyces and assembly into a hybrid vacuolar H+-ATPase.
G, Hughes, M A, Harrison, Y I, Kim, D E, Griffiths, M E, Finbow, J B, Findlay   +5 more
openaire   +2 more sources

Comprehensive Analysis of Malate Accumulation in Peaches in Response to Cold Stress Based on Transcriptomics

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
This study explored malate‐accumulation mechanisms in “Hujingmilu” peaches under different storage conditions. Low temperature (LT) delayed firmness decline and maintained higher malate. Transcriptomics showed malate biosynthetic genes weakly correlate with malate levels, while proton pump and transporter genes were up‐regulated under LT.
Hongfang Cai, Shuai Han, Xu Wang, Jiqing Shi, Zewen Xiong, Zheng Zhang, Zhuyi Gao   +6 more
wiley   +1 more source

Trichoderma genome and multiomics insight into promoting yield and reducing grain cadmium in barley and wheat

Journal of Integrative Plant Biology, Volume 68, Issue 1, Page 39-56, January 2026.
The fungal strain Trichoderma nigricans T32781 improved yield and reduced the grain cadmium concentrations of wheat and barley in cadmium‐polluted soils through microbial and metabolic interactions, offering a potential strategy for enhancing crop productivity and food safety in cadmium‐contaminated fields.
Shuo Zhang, Cheng‐Wei Qiu, Shou‐Heng Shi, Jakkrit Sreesaeng, Zi‐Feng Gao, Chulong Zhang, Weihua Mao, Mohamed Abdelalim Ali, Zhong‐Hua Chen, Feibo Wu   +9 more
wiley   +1 more source

Modulation of host cell pathways by Coxiella burnetii Dot/Icm effectors

mLife, Volume 4, Issue 6, Page 577-596, December 2025.
Abstract Coxiella burnetii, the etiological agent of Q fever, is a significant intracellular bacterial pathogen. C. burnetii is a highly infectious pathogen that primarily targets pulmonary alveolar macrophages during natural infection. It can then disseminate to macrophages in other tissues and organs, leading to chronic infections. C.
Jingya Yuan, Yong Zhang, Lei Song, Zhao‐Qing Luo   +3 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Laura Amarosi, Catriona M. H. Anderson, Philip M. Beart, Stefan Broer, Paul A. Dawson, Gergely Gyimesi, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Michal Hershfinkel, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Edmund R. S. Kunji, Gavin Stewart, Sotiria Tavoulari, David T. Thwaites, Tiziano Verri   +28 more
wiley   +1 more source

Deciphering the Sodium Sensing Mechanisms in Glycophytes and Halophytes

Plant, Cell &Environment, Volume 48, Issue 12, Page 8586-8603, December 2025.
ABSTRACT Plants, including halophytes (salt‐tolerant) and glycophytes (salt‐sensitive), have developed diverse molecular mechanisms and morphological adaptations to survive in saline environments. The cellular components and molecular processes for salinity sensing and stress tolerance have been extensively identified in glycophytes, but not so with ...
Rabia Areej Cheema, Hafiz Mamoon Rehman, Sehar Nawaz, Shakeel Ahmad, Hon‐Ming Lam   +4 more
wiley   +1 more source