Results 111 to 120 of about 142,204 (338)

The Computer‐Assisted Sequence Annotation (CASA) workflow for enzyme discovery

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise With the advent of inexpensive nucleic acid sequencing and automated annotation at the level of basic functionality, the central problem of enzyme discovery is no longer finding active sequences, it is determining which ones are suitable for further study.
Gemma R. Takahashi   +3 more
wiley   +1 more source

Chloroplast Protein Degradation in Senescing Leaves: Proteases and Lytic Compartments

open access: yesFrontiers in Plant Science, 2019
Leaf senescence is characterized by massive degradation of chloroplast proteins, yet the protease(s) involved is(are) not completely known. Increased expression and/or activities of serine, cysteine, aspartic, and metalloproteases were detected in ...
Agustina Buet   +3 more
doaj   +1 more source

Multinodular and Vacuolating Neuronal Tumor

open access: yesOpen Access Macedonian Journal of Medical Sciences, 2018
BACKGROUND: Multinodular and Vacuolating Neuronal Tumor (MVNT) of the cerebrum is a benign lesion described recently in the WHO CNS tumours in 2016. Although this tumour is uncommon, clinicians should be acquainted with the possible presentation and imaging findings.
Zahra, Charmaine, Grech, Reuben
openaire   +5 more sources

A novel imaging method revealed phosphatidylinositol 3,5-bisphosphate-rich domains in the endosome/lysosome membrane

open access: yesCommunicative & Integrative Biology, 2016
We developed a new method to observe distribution of phosphatidylinositol 3,5-bisphosphate [PtdIns(3,5)P2] using electron microscopy. In freeze-fracture replicas of quick-frozen samples, PtdIns(3,5)P2 was labeled specifically using recombinant ATG18 ...
Sho Takatori, Toyoshi Fujimoto
doaj   +1 more source

Auxin regulates SNARE-dependent vacuolar morphology restricting cell size

open access: yeseLife, 2015
The control of cellular growth is central to multicellular patterning. In plants, the encapsulating cell wall literally binds neighbouring cells to each other and limits cellular sliding/migration.
Christian Löfke   +3 more
doaj   +1 more source

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

open access: yesBMEMat, EarlyView.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan   +12 more
wiley   +1 more source

Lipidation-independent vacuolar functions of Atg8 rely on its noncanonical interaction with a vacuole membrane protein

open access: yeseLife, 2018
The ubiquitin-like protein Atg8, in its lipidated form, plays central roles in autophagy. Yet, remarkably, Atg8 also carries out lipidation-independent functions in non-autophagic processes. How Atg8 performs its moonlighting roles is unclear.
Xiao-Man Liu   +8 more
doaj   +1 more source

Calcineurin B-Like Proteins CBL4 and CBL10 Mediate Two Independent Salt Tolerance Pathways in Arabidopsis. [PDF]

open access: yes, 2019
In Arabidopsis, the salt overly sensitive (SOS) pathway, consisting of calcineurin B-like protein 4 (CBL4/SOS3), CBL-interacting protein kinase 24 (CIPK24/SOS2) and SOS1, has been well defined as a crucial mechanism to control cellular ion homoeostasis ...
Lan, Wen-Zhi   +6 more
core   +1 more source

The Vacuole Model: New Terms in the Second Order Deflection of Light

open access: yes, 2011
The present paper is an extension of a recent work (Bhattacharya et al. 2010) to the Einstein-Strauss vacuole model with a cosmological constant, where we work out the light deflection by considering perturbations up to order M^3 and confirm the light ...
A. Bhattacharya   +19 more
core   +1 more source

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