Results 181 to 190 of about 142,204 (338)

Cooperative Function of Atg8‐ and TORC1‐Mediated Activities in Yeast

open access: yesYeast, EarlyView.
The atg8Δ mutant is sensitive to rapamycin, and both lipidation‐dependent and ‐independent functions of Atg8 are necessary for survival during impaired TORC1 activity. Atg8‐ and TORC1‐mediated functions may contribute to maintaining vacuolar functions.
Yumiko Oba   +6 more
wiley   +1 more source

What are the consequences of water stress on the development of late postzygotic reproductive isolation in an orchid hybrid zone?

open access: yesPlant Species Biology, EarlyView.
Hybrids vulnerable to drought may increase postzygotic isolation in hybrid zones. Drought experiments can reveal the influence of climate change on hybrid zones. Crassulacean acid metabolism in parental species and hybrids was negatively affected by drought.
Karolyne Wanessa de Jesus   +6 more
wiley   +1 more source

The bacterial type three secretion system induces mechanoporation of vacuolar membranes. [PDF]

open access: yesPLoS Biol
Swistak L   +13 more
europepmc   +1 more source

Aging‐Associated Vacuolation of Multi‐Ciliated Cells in the Distal Mouse Oviduct Reflects Unique Cell Identity and Luminal Microenvironment

open access: yesAging Cell, EarlyView.
Multi‐ciliated cells in the infundibulum and ampulla (INF/AMP) epithelium are vacuolated in aging. Unique cellular susceptibility of the INF/AMP epithelial population and aging‐associated decline in ovarian artery circulation, which supports the ovary and INF/AMP, contribute to this region‐specific vacuolation phenotype, as a consequence of a mildly ...
Keerthana Harwalkar   +10 more
wiley   +1 more source

Age‐Associated Decline in Autophagy Pathways in the Retinal Pigment Epithelium and Protective Effects of Topical Trehalose in Light‐Induced Outer Retinal Degeneration in Mice

open access: yesAging Cell, EarlyView.
Transcriptomic analyses reveal an age‐related decline in autophagy pathways in RPE/choroid. These pathways remain unchanged in early AMD but become bidirectionally dysregulated in later stages, along with increased RPE loss. Pre‐treatment with trehalose eyedrops enhances RPE autophagy flux and prevents light‐induced outer retinal degeneration in mice ...
Katherine Cox   +13 more
wiley   +1 more source

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