Results 41 to 50 of about 232,600 (377)
Environmental or chemically induced stresses often trigger physiological responses that regulate intracellular pH. As such, the capacity to detect pH changes in real time and within live cells is of fundamental importance to essentially all aspects of ...
Hélène Tournu+3 more
doaj +1 more source
Pseudomonas aeruginosa utilizes the type III secreted toxin ExoS to avoid acidified compartments within epithelial cells. [PDF]
Invasive Pseudomonas aeruginosa (PA) can enter epithelial cells wherein they mediate formation of plasma membrane bleb-niches for intracellular compartmentalization.
Susan R Heimer+5 more
doaj +1 more source
Vacuoles in Bryophytes: Properties, Biogenesis, and Evolution
Vacuoles are the most conspicuous organelles in plants for their indispensable functions in cell expansion, solute storage, water balance, etc. Extensive studies on angiosperms have revealed that a set of conserved core molecular machineries orchestrate ...
Hao-ran Liu+8 more
doaj +1 more source
Calcium release through P2X4 activates calmodulin to promote endolysosomal membrane fusion [PDF]
Intra-endolysosomal Ca(2+) release is required for endolysosomal membrane fusion with intracellular organelles. However, the molecular mechanisms for intra-endolysosomal Ca(2+) release and the downstream Ca(2+) targets involved in the fusion remain ...
Baars+70 more
core +1 more source
The c-terminal extension of a hybrid immunoglobulin A/G heavy chain is responsible for its Golgi-mediated sorting to the vacuole [PDF]
We have assessed the ability of the plant secretory pathway to handle the expression of complex heterologous proteins by investigating the fate of a hybrid immunoglobulin A/G in tobacco cells.
Denecke, J. (Jurgen)+6 more
core +2 more sources
Gas vesicle formation and buoyancy regulation in Pelodictyon phaeoclathratiforme (Green sulfur bacteria) [PDF]
Gas vesicle formation and buoyancy regulation in Pelodictyon phaeoclathratiforme strain BU1 (Green sulfur bacteria) was investigated under various laboratory conditions.
Lehmann, Susanne+2 more
core +1 more source
A substrate localization model for the selective regulation of TORC1 downstream pathways
Target of rapamycin complex 1 (TORC1) is a protein kinase complex conserved in eukaryotes that coordinates diverse cellular processes critical for cell growth to environmental conditions.
Eigo Takeda, Akira Matsuura
doaj +1 more source
The entry of unclosed autophagosomes into vacuoles and its physiological relevance.
It is widely stated in the literature that closed mature autophagosomes (APs) fuse with lysosomes/vacuoles during macroautophagy/autophagy. Previously, we showed that unclosed APs accumulated as clusters outside vacuoles in Vps21/Rab5 and ESCRT mutants ...
Zulin Wu+17 more
doaj +1 more source
Cadmium (Cd) and arsenic (As) are toxic to all living organisms, including plants and humans. In plants, Cd and As are detoxified by phytochelatins (PCs) and metal(loid)-chelating peptides and by sequestering PC-metal(loid) complexes in vacuoles ...
Won-Yong Song+7 more
semanticscholar +1 more source
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica+6 more
wiley +1 more source