Results 41 to 50 of about 225,485 (404)
Urinary tract infections (UTIs) affect more than 150 million people, with a cost of over 3.5 billion dollars, each year. Escherichia coli is associated with 70–80% of UTIs. Uropathogenic E.
Juan Manuel Díaz+6 more
doaj +1 more source
The riddle of the plant vacuolar sorting receptors [PDF]
Proteins synthesized on membrane-bound ribosomes are sorted at the Golgi apparatus level for delivery to various cellular destinations: the plasma membrane or the extracellular space, and the lytic vacuole or lysosome. Sorting involves the assembly of vesicles, which preferentially package soluble proteins with a common destination.
arxiv +1 more source
Is gravitational collapse possible in $f(R)$ gravity? [PDF]
Gravitational collapse is still poorly understood in the context of $f(R)$ theories of gravity, since the Oppenheimer-Snyder model is incompatible with their junction conditions. In this work, we will present a systematic approach to the problem. Starting with a thorough analysis of how the Oppenheimer-Snyder construction should be generalised to fit ...
arxiv +1 more source
We studied the effects of bafilomycin A1, a potent and specific inhibitor of vacuolar H+ ATPase (V-ATPase), on the process of autophagy in rat hepatoma cell line, H-4-II-E cells.
A. Yamamoto+5 more
semanticscholar +1 more source
The Toxoplasma gondii active serine hydrolase 4 regulates parasite division and intravacuolar parasite architecture [PDF]
Hydrolase are enzymes that regulate diverse biological processes, including posttranslational protein modifications. Recent work identified four active serine hydrolases (ASHs) in Toxoplasma gondii as candidate depalmitoylases. However, only TgPPT1 (ASH1)
Amara, Neri+7 more
core +2 more sources
Endosymbiotic ratchet accelerates divergence after organelle origin
Primary endosymbiosis gave rise to mitochondria and plastids. The proximate impacts of organelle origin on lineage evolution have not been addressed at the population level. Using data from the photosynthetic amoeba Paulinella, we hypothesize that primary endosymbiosis accelerates lineage divergence, a process we refer to as the endosymbiotic ratchet ...
Debashish Bhattacharya+3 more
wiley +1 more source
More on Lensing by a Cosmological Constant [PDF]
The question of whether or not the cosmological constant affects the bending of light around a concentrated mass has been the subject of some recent papers. We present here a simple, specific and transparent example where $\Lambda$ bending clearly takes place, and where it is clearly neither a coordinate effect nor an aberration effect.
arxiv +1 more source
SUMMARYMany plant cells are characterized by the presence of a vacuole (hypertrophied lysosome) occupying a large fraction of the protoplast. The possible benefits of the presence of the vacuole can be divided into those which are related merely to the increased volume of the protoplast, independent of the nature of the vacuolar contents, and those ...
openaire +2 more sources
Anti-inflammatory effects of yeast-derived vacuoles on LPS-induced murine macrophage activation
Saccharomyces cerevisiae is a single-celled fungal microorganism. S. cerevisiae-derived vacuoles are closely related to mammalian lysosomes, which play a role in the degradation of macromolecules by various hydrolytic enzymes.
Su-Min Lee, Yang-Hoon Kim, Jiho Min
doaj +1 more source
Calcium release through P2X4 activates calmodulin to promote endolysosomal membrane fusion [PDF]
Intra-endolysosomal Ca(2+) release is required for endolysosomal membrane fusion with intracellular organelles. However, the molecular mechanisms for intra-endolysosomal Ca(2+) release and the downstream Ca(2+) targets involved in the fusion remain ...
Baars+70 more
core +1 more source