Results 41 to 50 of about 17,558 (180)

GABAB Receptor Signaling in the Dorsal Motor Nucleus of the Vagus Stimulates Gastric Motility via a Cholinergic Pathway

Frontiers in Neuroscience, 2019
Central nervous system regulation of the gastric tone and motility is primarily mediated via preganglionic neurons of the dorsal motor nucleus of the vagus (DMV).
Maureen T. Cruz, Ghazaul Dezfuli, Erin C. Murphy, Stefano Vicini, Niaz Sahibzada, Richard A. Gillis   +5 more
doaj   +1 more source

Activation of the Cholinergic Anti-inflammatory Pathway Attenuated Angiotension II-Dependent Hypertension and Renal Injury

Frontiers in Pharmacology, 2021
Background: Angiotensin II (AngII) induces renal fibrosis, characterized by fibroblast proliferation, inflammatory cell infiltration and excessive extracellular matrix deposition, all of which was relevant closely to hypertension. The vagus nerve-related
Shu-jie Wu, Zhe-wei Shi, Xue Wang, Fang-fang Ren, Zuo-yi Xie, Li Lei, Peng Chen   +6 more
doaj   +1 more source

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies

MedComm, Volume 7, Issue 2, February 2026.
The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Yan Fu, Zhi‐Shan Ge, Qing‐Yue Cao, Zi‐Han Li, An Zhang, Hai‐Dong Zhu, Gao‐Jun Teng   +6 more
wiley   +1 more source

Intermittent Fasting Alleviates Anesthesia/Surgery‐Induced Delirium‐Like Behavior in Aged Mice by Remodeling Gut Microbiota

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Preoperative intermittent fasting alleviates postoperative delirium‐like behaviors in aged mice by remodeling gut microbiota and preserving shortchain fatty acids. This gut‐brain interaction maintains hippocampal mitochondrial dynamics and synaptic plasticity, offering a promising non‐pharmacological strategy for perioperative neuroprotection. ABSTRACT
Peiying Huang, Longlu Cao, Tianyu Cao, Xueji Wang, Sichen Cui, Sufang Jiang, Huan Chen, Lichao Di, Sha Li, Lining Huang   +9 more
wiley   +1 more source

Locus coeruleus alterations in dementia with Lewy bodies: A systematic review

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 1, January/March 2026.
Abstract INTRODUCTION The locus coeruleus (LC) is a small nucleus located deep within the brainstem, serving as the brain's main source of noradrenergic neurons. Through its extensive projections, it plays a critical role in regulating cognitive processes and arousal.
Anaëlle Bain, Charlotte Tomeo, Claire André, Antoine Garnier‐Crussard, Robin de Flores, Sophie Dautricourt   +5 more
wiley   +1 more source

Defying gravity: Breath, beat and brain

Experimental Physiology, EarlyView.
Shigehiko Ogoh, Damian Miles Bailey
wiley   +1 more source

The Enteric Nervous System as a Mediator of Microbiota‐Gut‐Brain Interactions in Parkinson's Disease

Journal of Neurochemistry, Volume 170, Issue 1, January 2026.
Parkinson's disease (PD) is a neurodegenerative disorder that is increasingly recognized as a gut‐brain disorder, involving gut dysfunction before the onset of motor symptoms. While many studies have focused on changes in gut microbiota, inconsistent results highlight the limitations of viewing PD through a microbiota‐only lens.
Luisa Valdetaro, Maria Carolina Ricciardi, Patricia Pereira Almeida, Milena Barcza Stockler‐Pinto, Ana Lucia Tavares‐Gomes   +4 more
wiley   +1 more source

Wuda Granule Improves the Gastrointestinal Motility via Gut‐Brain Axis in Beagle Dogs

iMetaMed, Volume 1, Issue 2, December 2025.
Stress sensors were implanted in the gastric body, sinus, duodenum, jejunum, and colon of beagle dogs to record gastrointestinal motility. Gastrointestinal contractile motility was assessed before and after the lateral ventricular injection of Wuda granule, intravenous atropine instillation, and bilateral cervical vagotomy.
Zhi Jiang, Xing Li, Qicheng Chen, Zhiqiang Chen, Lixing Cao, Hailin Tang   +5 more
wiley   +1 more source

Microbiota‐gut‐brain axis multi‐organ chip construction and applications in drug evaluation

iMetaOmics, Volume 2, Issue 4, December 2025.
Microbiota‐gut‐brain axis multiorgan chip and its applications in drug evaluation. The chip includes essential biological components such as gut microbiota, gut barrier, blood‐brain barrier (BBB), and brain. This integrated platform incorporates neural (blue), endocrine (yellow), immune (pink), and metabolic (green) pathways to investigate the impact ...
Yue Tang, Hewen Chen, Ziyue Zhao, Xuesong Kang, Wenxin Wang, Kun Dai, Yufei Guo, Axin Liang, Aiqin Luo, Zikai Hao   +9 more
wiley   +1 more source