Results 41 to 50 of about 45,261 (260)

Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis [PDF]

The innate immune system protects against infection and tissue injury through the specialized organs of the reticuloendothelial system, including the lungs, liver, and spleen.
Ashok, Mala, Czura, Christopher J., Foxwell, Brian, Gallowitsch-Puerta, Margot, Huston, Jared M., Liao, Hong, Ochani, Kanta, Ochani, Mahendar, Pavlov, Valentin A., Rosas-Ballina, Mauricio, Tracey, Kevin J., Ulloa, Luis   +11 more
core   +2 more sources

Changes in extracellular pH during electrical stimulation of isolated rat vagus nerve [PDF]

, 1986
Double-barrelled pH-sensitive micro-electrodes were used to record changes of extracellular pH during repetitive stimulation of isolated rat vagus nerves. It was found that a small initial alkaline shift was followed by a prolonged acidification.
Ammann, Baker, Ballanyi, Bostock, Förstl, G. Ten Bruggencate, Gebert, Grafe, H. Bostock, Kraig, Mutch, P. Grafe, Ritchie, Ritchie, Steinhagen, Urbanics, W. Endres   +16 more
core   +1 more source

Emerging Therapeutic Strategies for Hearing Loss

Advanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han, Tian Shen, Weiwei He, Hao Wei, Xiaolong Zhao, Wen Yang, Chuan Bu, Xinghua Tang, Yu Zhao, Jiangang Fan   +9 more
wiley   +1 more source

Modulation of Neurally Mediated Vasodepression and Bradycardia by Electroacupuncture through Opioids in Nucleus Tractus Solitarius. [PDF]

, 2018
Stimulation of vagal afferent endings with intravenous phenylbiguanide (PBG) causes both bradycardia and vasodepression, simulating neurally mediated syncope.
Fu, Liang-Wu, Guo, Zhi-Ling, Longhurst, John C, Tjen-A-Looi, Stephanie C   +3 more
core   +3 more sources

Vagus Nerve Stimulator Implantation in Children [PDF]

Archives of Otolaryngology–Head & Neck Surgery, 2002
Vagus nerve stimulation was approved in 1997 as an adjunctive treatment of partial-onset seizures refractory to medical therapy. Subsequent to the initial clinical trials, few studies have been published specifically addressing perioperative management issues.To review the operative technique and perioperative management of patients undergoing vagus ...
Daniel J. Kirse, Richard D. Torkelson, Gregory W. Hornig, Thomas P. Eyen, Jerome V. Murphy, Andreas H. Werle, Daniel E. Bruegger   +6 more
openaire   +3 more sources

Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair

Advanced Science, EarlyView.
This review discusses various types of electrical stimulation sources and materials, delving into the roles and mechanisms of electrical stimulation therapy in plastic surgery for tissue repair. This work broadens the clinical perspective of electrical stimulation, covering diverse repair needs from bone to soft tissues, and provides insights into ...
Kexin Deng, Ruizeng Luo, Ying Chen, Xiaoqiang Liu, Yuanyin Xi, Muhammad Usman, Xupin Jiang, Zhou Li, Jiaping Zhang   +8 more
wiley   +1 more source

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

Advanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source

Autonomic regulation therapy to enhance myocardial function in heart failure patients: the ANTHEM-HFpEF study. [PDF]

, 2017
BackgroundApproximately half of the patients presenting with new-onset heart failure (HF) have HF with preserved left ventricular ejection fraction (HFpEF) and HF with mid-range left ventricular ejection fraction (HFmrEF).
Amurthur, Badri, Anand, Inder S, Ardell, Jeffrey L, DiCarlo, Lorenzo A, KenKnight, Bruce H, Kumar, H Uday, Libbus, Imad, Mittal, Sanjay, Premchand, Rajendra K   +8 more
core   +1 more source

Genetics‐Based Targeting Strategies for Precise Neuromodulation

Advanced Science, EarlyView.
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He, Zhidong Wei, Jianda Xu, Fei Jin, Tong Li, Lili Qian, Juan Ma, Weiying Zheng, Negar Javanmardi, Ting Wang, Kangjian Sun, Zhang‐Qi Feng   +11 more
wiley   +1 more source

Vagus Nerve Stimulation in Refractory Epilepsy: Effects on Pro- and Anti-Inflammatory Cytokines in Peripheral Blood [PDF]

, 2010
Objective: The vagus nerve has important immunological functions that may be relevant for its anticonvulsive action. We postulate that this anticonvulsive action is activated by a shift in the immune system resulting in a reduction of neurotoxic and an ...
Berfelo, M. W., Hulsman, J. A. R. J., Majoie, H. J. M., Myint, A., Rijkers, K., Schwarz, M., Vles, J. S. H.   +6 more
core   +2 more sources