Results 21 to 30 of about 8,668 (131)

Hearing loss in children with congenital cytomegalovirus infection

Revista Portuguesa Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, 2023
Objective: To study the prevalence of hearing loss in children with congenital Cytomegalovirus infection and the influence of the type of maternal infection, symptoms and neonatal treatment with valganciclovir.
Gonçalo Caetano Oliveira, Filipa Morgado, Mariana Santos, Clara Mota, Ricardo Matos, Raquel Robles, Rui Fonseca   +6 more
doaj   +1 more source

Congenital cytomegalovirus infection: features of the clinical course and catamnesis according to own observations

Журнал инфектологии, 2022
Congenital cytomegalovirus infection is the most common congenital infection, occurs in 0.6-5% of newborns worldwide, and is considered the leading non-genetic cause of sensorineural hearing loss in children.
E. V. Antsiferova, T. E. Taranushenko, D. G. Geninova, L. N. Karpova, L. A. Filippova, K. I. Karaganova, L. S. Karpova   +6 more
doaj   +1 more source

Valganciclovir for cytomegalovirus preemptive therapy in patients following allogeneic hematopoietic stem cell transplantation

Di-san junyi daxue xuebao, 2020
Objective and;To evaluate the clinical value of valganciclovir in preemptive treatment of cytomegalovirus (CMV) infection after allogeneic hematopoietic stem cell transplantation (allo-HSCT) by comparing the efficacy of the drug with other conventional ...
LU Xuan, YAN Han, XIA Linghui
doaj   +1 more source

Bilateral Vocal Cord Paralysis Following Influenza A: Case Report. [PDF]

Clin Case Rep
Flexible nasal endoscopy demonstrating bilateral vocal cord paralysis (BVCP) in the paramedian position. The left image demonstrates a glottic gap between the vocal cords (white arrows) in the maximally adducted position (patient saying “eeee”). Under normal circumstances the vocal cords should be touching with no glottic gap. The right image shows his
Tran DHV, Lay X, Cheung W, Lindsay B, Worrall B, Suresh S, Aggarwal A, Kol M, Wagh A, Cross R, Shah A.   +10 more
europepmc   +2 more sources

Experience of Using the Antiviral Therapy of Generalized Congenital Cytomegalovirus Infection

Детские инфекции (Москва), 2016
The article presents the results of observation and treatment with ganciclovir and oral valganciclovir form of a premature infant with congenital generalized symptomatic cytomegalovirus infection (CMVI) involving pathology of CNS, cholangitis ...
G. V. Petrova, V. I. Shakhgildyan, E. A. Chistozvonova, T. A. Pugacheva, N. V. Turkot, M. V. Egorova, O. U. Sautenko, I. B. Astasheva, O. V. Romanova, N. V. Kostycheva, T. A. Grigorieva, M. G. Kulagina   +11 more
doaj   +1 more source

Transient Azoospermia Induced by Valganciclovir Treatment for Cytomegalovirus Infection in a Reproductive Male After Kidney Transplant: A Case Report

IJU Case Reports
Introduction Spermatogenic dysfunction is a side effect of valganciclovir, which is commonly used to treat cytomegalovirus infections. Here, we report the case of a reproductive man who underwent kidney transplantation and was diagnosed with azoospermia ...
Kosuke Mieda, Shunta Hori, Mitsuru Tomizawa, Kuniaki Inoue, Tatsuo Yoneda, Yuji Nitta, Yasushi Nakai, Makito Miyake, Nobumichi Tanaka, Kiyohide Fujimoto   +9 more
doaj   +1 more source

Treatment of cytomegalovirus anterior segment infection with intravitreal injection of ganciclovir in adjunction with or without oral valganciclovir: a long-term results

Scientific Reports, 2021
We evaluated the therapeutic outcome of intravitreal injection (IVI) of ganciclovir with/without oral valganciclovir for cytomegalovirus (CMV) anterior segment infection.
Yu-Chun Cheng, Eugene Yu-Chuan Kang, Yih-Shiou Hwang, Ching-Hsi Hsiao   +3 more
doaj   +1 more source

Newly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators

The FEBS Journal, EarlyView.
Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner, Yan Yan Beer, H. G. Mauricio Ramm, Sabrina Mühlen, Frank Surup, Jennifer Herrmann, Toni Luise Meister, Stephanie Pfaender, Ursula Bilitewski, Mark Brönstrup, Rolf Müller, Manfred Wirth, Eeva‐Liisa Eskelinen, Ingo Schmitz   +13 more
wiley   +1 more source

The Role of Belatacept‐Use and Senescence on Infectious and Mortality Complications After Kidney Transplantation

Transplant Infectious Disease, EarlyView.
ABSTRACT Introduction Studies evaluating the incidence of infections after belatacept as a substitute for calcineurin inhibitors (CNI) or antimetabolite in kidney transplant (KT) yielded conflicting results. We compared infectious outcomes after belatacept‐use to no belatacept‐use in KT recipients.
Hareesh Singam, Abdinoor Abdi, Wyatt Tarter, Ben Langworthy, Adam Bregman, Karam M. Obeid   +5 more
wiley   +1 more source

Pediatric Dosing of Ganciclovir and Valganciclovir: How Model‐Based Simulations Can Prevent Underexposure and Potential Treatment Failure

CPT: Pharmacometrics & Systems Pharmacology, 2019
Intravenous ganciclovir and oral valganciclovir are effective in the prevention and treatment of pediatric cytomegalovirus (CMV) infection but various dosing regimens are used in medical practice.
Karin Jorga, Bruno Reigner, Clarisse Chavanne, Giuseppe Alvaro, Nicolas Frey   +4 more
doaj   +1 more source