Results 81 to 90 of about 6,428,897 (326)
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
, 2012 Linear principal component analysis (PCA) can be extended to a nonlinear PCA by using artificial neural networks. But the benefit of curved components requires a careful control of the model complexity.
A Herman +26 more
core +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
A Multi‐Dimensional Approach to Map Disease Relationships Challenges Classical Disease Views
Advanced ScienceThe categorization of human diseases is mainly based on the affected organ system and phenotypic characteristics. This is limiting the view to the pathological manifestations, while it neglects mechanistic relationships that are crucial to develop ...
Lena Möbus +5 more
doaj +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Model validation of spatiotemporal systems using correlation function tests [PDF]
, 2006 Model validation is an important and essential final step in system identification. Although model validation for nonlinear temporal systems has been extensively studied, model validation for spatiotemporal systems is still an open question.
Billings, S.A., Pan, Y.
core
Efficient algorithms for decision tree cross-validation
, 2001 Cross-validation is a useful and generally applicable technique often employed in machine learning, including decision tree induction. An important disadvantage of straightforward implementation of the technique is its computational overhead.
Blockeel, Hendrik, Struyf, Jan
core +4 more sources
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Journal of Mechanical Engineering and Sciences, 2019 The accuracy of the predicted dynamic behaviour of an assembled structure using the frequency based substructuring (FBS) method is often found to be diverged from the experimental counterparts.
W. I. I. Wan Iskandar Mirza +4 more
doaj +1 more source
Microservices Validation: Methodology and Implementation [PDF]
, 2015 Due to the wide spread of cloud computing, arises actual question about architecture, design and implementation of cloud applications. The microservice model describes the design and development of loosely coupled cloud applications when computing ...
Radchenko, G., Savchenko, D.
core