Results 81 to 90 of about 7,539,132 (320)

Validation issues in educational data mining:the case of HTML-Tutor and iHelp [PDF]

open access: yes, 2010
Validation is one of the key aspects in data mining and even more so in educational data mining (EDM) owing to the nature of the data. In this chapter, a brief overview of validation in the context of EDM is given and a case study is presented. The field
Cocea, Mihaela, Weibelzahl, Stephan
core   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

open access: yesNucleic Acids Res., 2007
MolProbity is a general-purpose web server offering quality validation for 3D structures of proteins, nucleic acids and complexes. It provides detailed all-atom contact analysis of any steric problems within the molecules as well as updated dihedral ...
Ian W. Davis   +11 more
semanticscholar   +1 more source

Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor

open access: yesNature Communications, 2022
Meprin α is a proteolytic regulator of the extracellular matrix that forms enormous oligomeric filaments of unknown purpose. Here, the authors determine by cryo-EM the structural basis of the meprin supercoiled filament and further characterise a small ...
Charles Bayly-Jones   +10 more
doaj   +1 more source

Validation in the Software Metric Development Process [PDF]

open access: yes, 1995
In this paper the validation of software metrics will be examined. Two approaches will be combined: representational measurement theory and a validation network scheme.
Berg, K.G. van den, Broek, P.M. van den
core   +2 more sources

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

Multiplicative local linear hazard estimation and best one-sided cross-validation [PDF]

open access: yes, 2017
This paper develops detailed mathematical statistical theory of a new class of cross-validation techniques of local linear kernel hazards and their multiplicative bias corrections.
Gámiz Pérez, M. L.   +2 more
core   +1 more source

Validation of Voting Committees [PDF]

open access: yes, 1997
This article contains a method to bound the test errors of voting committees with members chosen from a pool of trained classifiers. There are so many prospective committees that validating them directly does not achieve useful error bounds.
Bax, Eric
core   +4 more sources

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

The will and the ways: development and validation of an individual-differences measure of hope.

open access: yesJournal of Personality and Social Psychology, 1991
Defining hope as a cognitive set that is composed of a reciprocally derived sense of successful (a) agency (goal-directed determination) and (b) pathways (planning of ways to meet goals), an individual-differences measure is developed.
C. R. Snyder   +9 more
semanticscholar   +1 more source

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