Results 21 to 30 of about 138,885 (211)
Advanced Science, EarlyView.A novel multiscale MD/DFT framework to elucidate microenzyme adsorption and electron transfer is reported. This method reveals distinct configurations for microperoxidase‐11 on graphene and those best suited for electron transfer. Rate constants align with the limited experimental data, establishing this framework as a tool for optimizing microenzyme ...
Milan Mijajlovic +6 more
wiley +1 more source
SiDT1 Defines Plant Architecture Reminiscent of Green Revolution in Foxtail Millet
Advanced Science, EarlyView.SiDT1 encodes a GA3‐oxidase that creates a semi‐dwarf, lodging‐resistant architecture reminiscent of the rice Green Revolution. The resulting ideotype performs well under dense planting and provides a valuable genetic resource for high‐yield, mechanized foxtail millet production. ABSTRACT Foxtail millet (Setaria italica) is a drought‐tolerant C4 cereal
Jianzhen Lv +13 more
wiley +1 more source
Cell‐Selective Delivery of RIBOTACs via an Anti‐EGFR Nanobody for Pancreatic Cancer Treatment
Advanced Science, EarlyView.This study introduces an innovative strategy for the tumor‐selective catalytic degradation of oncogenic non‐coding RNA by interfacing a ribonuclease‐recruiting small molecule (RIBOTAC) with an EGFR‐targeting nanobody via a CTSB (Cathepsin B)‐responsive linker.
Tianli Luo +15 more
wiley +1 more source
A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers
Advanced Science, EarlyView.Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels +2 more
wiley +1 more source
Cyclo(valine–valine) inhibits Vibrio cholerae virulence gene expression
Microbiology, 2014 Vibrio cholerae has been shown to produce a cyclic dipeptide, cyclo(phenylalanine–proline) (cFP), that functions to repress virulence factor production. The objective of this study was to determine if heterologous cyclic dipeptides could repress V. cholerae virulence factor production.
Amit, Vikram +5 more
openaire +2 more sources
Advanced Science, EarlyView.Super‐multiplexed Label‐free Raman Imaging (SLRI) enables 2D/3D metabolic mapping of intact Drosophila testes. Moving beyond descriptive morphology, it establishes a multidimensional tool for tissue metabolic remodeling, and offers a generalizable platform for complex tissue analysis, with implications extending to development and disease. ABSTRACT The
Jiaxin Li +23 more
wiley +1 more source
THE SOLUBILITY OF d-VALINE IN WATER [PDF]
Journal of General Physiology, 1936 1. The solubility of d-valine in water has been determined over a range of 0–60°. 2. The solubility of this amino acid varies with the mode of crystallization, indicating a dependence of solubility on the crystal form.
J B, Dalton, C L, Schmidt
openaire +2 more sources
Advanced Science, EarlyView.Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries +25 more
wiley +1 more source
Valine Requirement for Reproduction in Swine
Journal of Animal Science, 1983 Five levels of L-valine [3.3 (basal), 5.5, 7.8, 10.1 and 12.4 g/d] were fed to gilts from one estrus before mating through two pregnancies and for 30 d of a third pregnancy. Five litter-mate outcome groups of five animals each were allocated randomly to the diet treatments. Animals were individually fed 1.82 kg/d premating and during pregnancy.
A, Robles-Cabrera, V C, Speer
openaire +3 more sources
Advanced Science, EarlyView.An alternating current (AC)‐promoted, Pd‐catalyzed ortho‐aryl C─H alkynylation of 2,3‐diaryl acrylaldehydes is described. This synthetic scheme accommodates a broad substrate scope, delivering alkynylated stilbene derivatives with excellent arene site selectivity.
Junya Wang +7 more
wiley +1 more source