Results 21 to 30 of about 138,081 (263)

Hypolipemiant Actions and Possible Cardioprotective Effects of Valine and Leucine: An Experimental Study

Medicina, 2021
Background and Objectives: Considering atherosclerosis as one of the more challenging threats to healthcare worldwide, any novel therapy that counteracts the risks for developing it, provides new opportunities for the management of this process. Material
Elena Cojocaru, Maria Magdalena Leon-Constantin, Carmen Ungureanu, Mioara Florentina Trandafirescu, Alexandra Maștaleru, Laura Mihaela Trandafir, Florin Dumitru Petrariu, Oana Viola Bădulescu, Nina Filip   +8 more
doaj   +1 more source

Diaqua(nitrato-κ2O,O′)bis(l-valine-κO)lead(II) nitrate at 296 K

IUCrData, 2016
The structure of the title complex, [Pb(NO3)(C5H11NO2)2(H2O)2]NO3, had been determined previously at 173 and 193 K, and is now reported at 296 K, in the same space group.
Sylvain Bernès, Laura Gasque
doaj   +1 more source

Amino acid content and biomass productivity of selected weed species as an indicator of their response to herbicide stress

Acta Agrobotanica, 2013
Biomass reduction and amino acid content in plants of Papaver rhoeas L. and Stellaria media L. were investigated to evaluate response of these species to herbicide stress under various temperature (25/16 and 8/2 oC) and relative humidity (50 and 75 ...
Renata Kieloch, Jerzy Sadowski, Krzysztof Domaradzki   +2 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Exploring Valine Metabolism in Astrocytic and Liver Cells: Lesson from Clinical Observation in TBI Patients for Nutritional Intervention

Biomedicines, 2020
The utilization of alternative energy substrates to glucose could be beneficial in traumatic brain injury (TBI). Recent clinical data obtained in TBI patients reported valine, β-hydroxyisobutyrate (ibHB) and 2-ketoisovaleric acid (2-KIV) as three of the ...
Sarah Sonnay, Nicolas Christinat, Jonathan Thevenet, Andreas Wiederkehr, Anirikh Chakrabarti, Mojgan Masoodi   +5 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Investigating the causal association between branched-chain amino acids and Alzheimer's disease: A bidirectional Mendelian randomized study

Frontiers in Nutrition, 2023
BackgroundThere are many metabolic pathway abnormalities in Alzheimer's disease (AD). Several studies have linked branched-chain amino acid (BCAA) metabolism disorders with AD but have not obtained consistent results.
Xiao-hang Qian, Xiao-hang Qian, Xiao-hang Qian, Xiao-li Liu, Bin Zhang, Yuan Lin, Jian-hua Xu, Gang-yu Ding, Hui-dong Tang, Hui-dong Tang, Hui-dong Tang   +10 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Valine metabolite, 3-hydroxyisobutyrate, promotes lipid metabolism and cell proliferation in porcine mammary gland epithelial cells

Frontiers in Nutrition
Improving mammary gland epithelial cells proliferation through nutrition is an important approach for enhancing sow milk production and piglet growth. An intermediate metabolite of valine, 3-hydroxyisobutyrate (3-HIB), regulates cellular lipid metabolism.
Long Che, Long Che, Long Che, Le Liu, Mengmeng Xu, Zongze Fan, Lizhu Niu, Yujie Chen, Xueyuan Chang, Pan Zhou, Mengyun Li, Hongyu Deng, Wen Chen   +12 more
doaj   +1 more source

Antioxidant Activity of New Aramide Nanoparticles Containing Redox-Active <em>N</em>-phthaloyl Valine Moieties in the Hepatic Cytochrome P₄₅₀ System in Male Rats

Molecules, 2012
We report the synthesis of aramide nanoparticles containing a chiral <em>N</em>-phthaloyl valine moiety and their antioxidant activities on hepatic contents of cytochrome P₄₅₀, amidopyrene <em>N</em> ...
Hammed H. A. M. Hassan, Sabah G. El-Banna, Amel F. Elhusseiny, El-Sayed M. E. Mansour   +3 more
doaj   +1 more source