Results 1 to 10 of about 74,623 (302)
Serum concentrations of valproic acid in people with epilepsy: Clinical implication [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2022 Context: Therapeutic drug monitoring (TDM) allows personalizing the dose of valproic acid in patients with epilepsy to optimize drug therapy, minimize adverse effects and detect interactions.
Angel T. Alvarado +12 more
doaj +2 more sources
Nomogram for the prediction of valproic acid induced platelet decline: a nested case–control study [PDF]
Scientific ReportsPlatelet decline is a frequent side effect of valproic acid, a medication commonly prescribed to prevent seizures in neurosurgical patients. However, the risk factors for valproic acid-associated platelet decline remain poorly understood, and it remains ...
Gang Cheng +6 more
doaj +2 more sources
Retrospective Analysis of 2 992 Times of Therapeutic Drug Monitoring of Valproic Acid from 2019 to 2021 [PDF]
Zhongguo quanke yixue, 2023 Background Valproic acid, as a mood stabilizer, has been extensively used for the treatment of bipolar disorder and other psychiatric conditions. Although therapeutic drug monitoring (TDM) of valproic acid has been carried out at home and abroad for many
DING Jing, MENG Zhuocheng, ZHANG Yan, CUI Xiaohua, LIU Jiarui, HE Jiao, ZHANG Yang, LI Yajuan, YANG Liu
doaj +1 more source
Use of valproic acid in long stay units of psychiatry [PDF]
Farmacia Hospitalaria, 2015 Objective: Valproic acid is often used in psychiatry to treat schizophrenia and other conditions outside of indication (“off-label”). However, its effectiveness has not been sufficiently demonstrated and its use is not exempt of adverse effects.
Mª Teresa Martínez-Lazcano +5 more
doaj +1 more source
Genetic Polymorphisms Associated with Valproic Acid Therapy: Review article
SVU - International Journal of Medical Sciences, 2022 Background: Valproic acid is an important anticonvulsant and mood-stabilizing drug. It is also used in the therapy of bipolar disorders, migraine, cancer and neurodegenerative disorders.
Reham A.M. Ellisy* +4 more
doaj +1 more source
Scientific Reports, 2021 Valproic acid is an anticonvulsant, which is also widely used for treating psychiatric disorders. Some clinical trials have demonstrated benefits of valproic acid augmentation therapy in schizophrenia.
S. Wang +7 more
doaj +1 more source
Resistance after chronic application of the HDAC-inhibitor valproic acid is associated with elevated Akt activation in renal cell carcinoma in vivo [PDF]
, 2013 Targeted drugs have significantly improved the therapeutic options for advanced renal cell carcinoma (RCC). However, resistance often develops, negating the benefit of these agents.
Bartsch, Georg +6 more
core +11 more sources
Pharmacological modulation of cell functional activity with valproic acid and erythropoietin [PDF]
Research Results in Pharmacology, 2019 Introduction: Valproic acid (VA) is carboxylic acid with a branched chain, which is used as an antiepileptic drug. Valproic acid influence on cells in vivo: VA, which is an antiepileptic drug, is also a teratogen, which causes defects ...
Polina A. Golubinskaya +8 more
doaj +3 more sources
Pharmaceuticals, 2023 Genetic polymorphisms in ATP-binding cassette subfamily B member 1 (ABCB1, also known as MDR1) have been reported to be possibly associated with the regulation of response to antiseizure medications.
Jiahao Zhu +7 more
doaj +1 more source