Results 91 to 100 of about 74,623 (302)

Rapid recovery after intrathecal dexamethasone in FIRES

Epileptic Disorders, EarlyView.
João Filipe Nico, Ana Rita Fradique, Catarina Teixeira, Rita Moinho, Mariana Leitão Marques, Constança Santos, Joana Afonso Ribeiro, Filipe Palavra, Cristina Pereira   +8 more
wiley   +1 more source

Efficacy and safety of perampanel as first adjunctive therapy in patients with focal‐onset seizures or generalized tonic‐clonic seizures in four post‐marketing studies across regions

Epilepsia Open, EarlyView.
Abstract Objective Early response to anti‐seizure medication (ASM) is associated with a favorable prognosis in patients with epilepsy. Research is required to confirm existing data on the clinical use of perampanel as first adjunctive therapy in different patient groups and different regions.
Stefano Meletti, Vineet Punia, Amitabh Dash, Anna Lisa Gentile, Ricardo Sáinz‐Fuertes, Samantha Goldman, Tobias Goldmann, Anna Patten, Dinesh Kumar, Leock Y. Ngo, Bernhard J. Steinhoff   +10 more
wiley   +1 more source

Effect of valproic acid on Expression of Bim gene and viability of ovarian cancer cell line A2780

مجله دانشگاه علوم پزشکی گرگان, 2017
Background and Objective: Ovarian cancer is the fifth common cancer among women and the number of new cases is increasing. Valproic acid is a histone deacetylase inhibitor effectively used to treat epilepsy and bipolar disease.
Z Amini-Farsani, MH Sangtarash, H Teimori, M Shamsara   +3 more
doaj  

Lennox–Gastaut syndrome in a patient with biallelic TELO2 variants

Epileptic Disorders, EarlyView.
Melissa Odabassian, Kenneth A. Myers
wiley   +1 more source

Stiripentol use in Dravet syndrome patients in the USA: Results of a real‐world study

Epilepsia Open, EarlyView.
Abstract Objective Dravet syndrome (DS) is a severe developmental and epileptic encephalopathy with a high seizure burden and mortality risk. Stiripentol, one of the first DS‐specific therapies, received FDA approval in 2018 but its real‐world use and impact post‐approval in the USA remain insufficiently characterized.
Elaine Wirrell, James Wheless, Michael Scott Perry, Linda Laux, Karen C. Keough, Julie Ziobro, Aimee F. Luat, Gewalin Aungaroon, Michael A. Ciliberto, Roxane Noel, Laurent Chancharme, Joseph Sullivan   +11 more
wiley   +1 more source

Valproate-induced thrombocytopenia

Лечащий Врач
Background. Valproic acid is widely prescribed as an antiepileptic drug and mood stabilizer. Fatigue, tremor, sedation, hepatotoxicity, weight gain, hair loss and thrombocytopenia have been reported as side effects.
N. V. Izmozherova, A. A. Popov, I. P. Antropova, L. I. Kadnikov, D. A. Kruzhevnikova, O. A. Makarova   +5 more
doaj   +1 more source

Cognitive safety under epicranial cortex stimulation of the epileptic focus

Epilepsia Open, EarlyView.
Abstract Epicranial focal cortex stimulation (FCS) is a new CE‐certified treatment for pharmacoresistant focal epilepsy. In a multicenter observational trial, we report cognitive tolerability in 11 patients with pharmacoresistant epilepsy undergoing epicranial focal cortex stimulation (eFCS) over the predominant seizure focus (left temporal (N = 4 ...
Kathrin Wagner, Iris Gorny, Julia Kustermann, Jessika Paula Losacker, Birgitta Metternich, Julia Berg, Bastian E. A. Sajonz, Volker Arnd Coenen, Elisabeth Kaufmann, Susanne Knake, Andreas Schulze‐Bonhage   +10 more
wiley   +1 more source

A Theoretical Method for Normalizing Total Serum Valproic Acid Concentration in Hypoalbuminemic Patients

Journal of Pharmacological Sciences, 2005
In patients with hypoalbuminemia, the total serum concentration of valproic acid may offer poor clinical information; however, very few clinical laboratories routinely analyze the free concentration of the drug.
Jesús Hermida, J. Carlos Tutor
doaj   +1 more source

Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review

Food Frontiers, EarlyView.
Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv, Yuanyuan Huang, Mokhtar Dabbour, Benjamin Kumah Mintah, Ronghai He, Haile Ma   +5 more
wiley   +1 more source

Effect of valproic acid and radiotherapy on viability of MCF-7 breast cancer cell line

مجله دانشگاه علوم پزشکی گرگان, 2014
Background and Objective: Valproic acid is used in the epilepsy, bipolar and migraine therapy. As a histone deacetylase inhibitor, Valproic acid has been recently under investigation in cancer treatment, either alone or in combination with either ...
Aghagolzade Haji H, Khoshbin Khoshnazar AR, Gharaei R, Javan B, Asadi J   +4 more
doaj