Results 71 to 80 of about 35,696 (248)

Epileptic encephalopathy with spike‐and‐wave activation in sleep associated with Tatton–Brown–Rahman syndrome responsive to highly purified cannabidiol

Epileptic Disorders, EarlyView.
Anita N. Datta
wiley   +1 more source

Efficacy of fenfluramine in a pediatric epilepsy patient with a pathogenic SV2A variant: A case report

Epileptic Disorders, EarlyView.
Abstract Pathogenic SV2A gene variants have been reported as causes of epilepsy and are often associated with drug resistance and susceptibility to fever‐related seizures. No highly effective treatments have been established for this condition. We report a female patient with a family history of epilepsy who developed generalized seizures associated ...
Takayuki Mori, Hiroshi Terashima, Yu kakimoto, Mitsuhiro Kato, Shumpei Uchino   +4 more
wiley   +1 more source

Decrease in the effectiveness of valproic acid against the background of antibacterial therapy with imipenem/cilastatin in pediatric practice: A case report

Сибирский научный медицинский журнал
A clinical case of the co-medication of valproic acid and cilastatin/imipenem in a 17-year-old girl with generalized tonic-clonic seizures is described.
A. B. Strok, M. S. Chenkurov, M. N. Kostyleva, D. A. Umutkuzina   +3 more
doaj   +1 more source

Valproic Acid Induced Hyperammonemia in a Long Time Treated Patient

Case Reports in Psychiatry, 2016
We report a case of a patient who had been on long time valproic acid for treatment of bipolar affective disorder. While being an inpatient, serology ammonia level testing revealed a very high ammonia level despite being asymptomatic.
Rohit Aiyer, Margaret Seide, Robert G. Stern   +2 more
doaj   +1 more source

Management of ring chromosome 20 syndrome: Narrative review and consensus recommendations

Epilepsia, EarlyView.
Abstract Ring chromosome 20 (ring 20) is a rare genetic condition usually presenting as developmental and epileptic encephalopathy. The disease is caused by fusion of the long and short arms of chromosome 20. Patients are symptomatic even if there is no loss of genetic material.
Asma Khamis, Emilia Ricci, Maria Paola Canevini, Lieven Lagae, Kentaro Tokumoto, Yushi Inoue, Tim Buckinx, Allison Watson, Kenneth A. Myers   +8 more
wiley   +1 more source

Unveiling Thrombocytopenia Trends In Pediatric Epilepsy: The Valproate Connection

Journal of Rawalpindi Medical College
Objective: To determine the frequency and association of thrombocytopenia in patients on valproate therapy in the Pediatrics department of Pakistan Atomic Energy Hospital, Islamabad.
Kiran Nayab, Qurrat ul Ain, Ayesha Tariq, Israr Liaqat, Samra Javed, Nadia Mumtaz   +5 more
doaj   +1 more source

Corticocortical evoked potential amplitude is altered by cortical stimulation in epilepsy

Epilepsia, EarlyView.
Abstract Objective Neurostimulation is an established therapy for drug‐resistant epilepsy, but optimizing stimulation parameters remains a major challenge. Corticocortical evoked potential (CCEP) amplitude may serve as an immediate biomarker of neurostimulation effects, enabling rapid parameter optimization.
Bethany J. Stieve, Aaron F. Struck, Dillon Scott, Richard Chappell, Andrew T. Knox   +4 more
wiley   +1 more source

Betaine reduces valproic acid-induced hepatotoxicity [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: Antiepileptic drugs  cause a wide range of side effects in patients, including hepatotoxicity particularly associated with valproic acid.
Amin Hasanvand, Parian Mahmoudi, Ali Rashidiani-Rashidabadi, Mohsen Mohammadi, Alimohammad Maleki, Sirous Jafari Zafarabadi, Hamidreza Mohammadi   +6 more
doaj  

Clinical Vignette: A rare pericallosal lipoma presenting with Lennox–Gastaut syndrome and a remarkable response to valproic acid

Epileptic Disorders, EarlyView.
Rainier Mark Loidor L. Rapal, Hok Leong Chin, Douglas Nordli III   +2 more
wiley   +1 more source

A translational multimodal machine‐learning prototype predicting valproate response in epilepsy treatment

Epilepsia, EarlyView.
Abstract Objective Epilepsy affects ~1% of the global population and often requires lifelong antiseizure medication (ASM) therapy. Valproic acid (VPA) is a commonly prescribed first‐line ASM, yet only approximately half of patients achieve sustained seizure freedom. Treatment selection remains largely empirical.
Simeon Platte, Afsheen Kumar, Giorgia Guerini, Massimo Pandolfo, Denise Haslinger, Colin B. Josephson, Guillermo Delgado‐García, Navprabhjot Kaur, Michaela‐Pauline Lux, Heiko Stempfle, Chantal Depondt, Reetta Kälviäinen, Felix Rosenow, Sophie von Brauchitsch, Karl Martin Klein, Andreas G. Chiocchetti   +15 more
wiley   +1 more source