Results 11 to 20 of about 5,054,451 (380)
Ellagic acid attenuates liver toxicity induced by valproic acid in rats
Journal of Pharmacological Sciences, 2020 Valproic acid is a commonly used drug for many psychiatric disorders, particularly for epilepsy. However, it has been reported that its use is associated with possible side effects including hepatotoxicity.The present study investigated the ...
Noha F. Abdelkader +5 more
doaj +2 more sources
Therapeutic and Toxic Effects of Valproic Acid Metabolites
Metabolites, 2023 Valproic acid (VPA) and its salts are psychotropic drugs that are widely used in neurological diseases (epilepsy, neuropathic pain, migraine, etc.) and psychiatric disorders (schizophrenia, bipolar affective disorder, addiction diseases, etc.).
N. Shnayder +10 more
semanticscholar +1 more source
Frontiers in Physiology, 2023 Introduction: The microbiota–gut–brain axis plays an important role in the pathophysiology of autism spectrum disorder, but its specific mechanisms remain unclear.
Jiugen Zhong +7 more
semanticscholar +1 more source
Epilepsia, 2021 This study aimed at estimating the cumulative incidence of antiepileptic drug (AED) treatment failure of first‐line monotherapy levetiracetam vs valproic acid in glioma patients with epilepsy.
P. B. van der Meer +7 more
semanticscholar +1 more source
Valproic Acid and Breast Cancer: State of the Art in 2021
Cancers, 2021 Simple Summary Breast cancer (BC) is the most common cancer diagnosed among women worldwide. Despite numerous studies, the pathogenesis of BC is still poorly understood, and effective therapy of this disease remains a challenge for medicine. This article
A. Wawruszak +4 more
semanticscholar +1 more source
Insights into Structural Modifications of Valproic Acid and Their Pharmacological Profile
Molecules, 2021 Valproic acid (VPA) is a well-established anticonvulsant drug discovered serendipitously and marketed for the treatment of epilepsy, migraine, bipolar disorder and neuropathic pain.
M. Mishra +9 more
semanticscholar +1 more source
Genetic Polymorphisms Associated with Valproic Acid Therapy: Review article
SVU - International Journal of Medical Sciences, 2022 Background: Valproic acid is an important anticonvulsant and mood-stabilizing drug. It is also used in the therapy of bipolar disorders, migraine, cancer and neurodegenerative disorders.
Reham A.M. Ellisy* +4 more
doaj +1 more source
Scientific Reports, 2021 Valproic acid is an anticonvulsant, which is also widely used for treating psychiatric disorders. Some clinical trials have demonstrated benefits of valproic acid augmentation therapy in schizophrenia.
S. Wang +7 more
doaj +1 more source
Pharmacological modulation of cell functional activity with valproic acid and erythropoietin [PDF]
Research Results in Pharmacology, 2019 Introduction: Valproic acid (VA) is carboxylic acid with a branched chain, which is used as an antiepileptic drug. Valproic acid influence on cells in vivo: VA, which is an antiepileptic drug, is also a teratogen, which causes defects ...
Polina A. Golubinskaya +8 more
doaj +3 more sources
Pharmaceuticals, 2023 Genetic polymorphisms in ATP-binding cassette subfamily B member 1 (ABCB1, also known as MDR1) have been reported to be possibly associated with the regulation of response to antiseizure medications.
Jiahao Zhu +7 more
doaj +1 more source