Results 21 to 30 of about 74,623 (302)
Valproic Acid-induced Agranulocytosis
International Journal of Gerontology, 2009 Valproic acid is considered to be the most well-tolerated antiepileptic drug. However, few cases of neutropenia or leukopenia caused by valproic acid have been reported. We present a patient who took valproic acid to treat a complication of brain surgery
Hui-Chuan Hsu +3 more
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Clinical and Translational Science, 2023 Cisplatin treatment is effective against several types of carcinomas. However, it frequently leads to kidney injury, which warrants effective prevention methods.
Toshihiko Yoshioka +13 more
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Fatal Hyperammonemic Brain Injury from Valproic Acid Exposure [PDF]
, 2012 Background: Hyperammonemia is known to cause neuronal injury, and can result from valproic acid exposure. Prompt reduction of elevated ammonia levels may prevent permanent neurological injury.
Bega, Danny +4 more
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Meropenem-induced Valproic Acid Elimination: A Case Report of Clinically Relevant Drug Interaction
Prague Medical Report, 2017 We present two case reports of drug interaction between valproic acid and meropenem. In comparison with expected population-kinetic based serum levels, we observed 90.8 and 93.5% decrease in valproic acid serum levels during concomitant administration ...
Martin Šíma +4 more
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Modeling Autistic Features in Animals [PDF]
, 2011 A variety of features of autism can be simulated in rodents, including the core behavioral hallmarks of stereotyped and repetitive behaviors, and deficits in social interaction and communication.
Patterson, Paul H.
core +1 more source
Antidepressant effects of valproic acid in an animal model of depression
European Pharmaceutical Journal, 2019 Valproic acid, beside its anticonvulsant action, is widely used as a mood stabilizer in the therapy of bipolar disorder. The potential antidepressant action of valproic acid has not been sufficiently characterized so far. The aim of the present study was
Buzgoova K. +3 more
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Frontiers in Cell and Developmental Biology, 2022 Neuroinflammation is a critical and targetable pathogenic component of neurodegenerative diseases, including glaucoma, the leading cause of irreversible blindness.
James R. Tribble +5 more
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Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism. [PDF]
, 2017 Most differentiated cells convert glucose to pyruvate in the cytosol through glycolysis, followed by pyruvate oxidation in the mitochondria. These processes are linked by the mitochondrial pyruvate carrier (MPC), which is required for efficient ...
A Ootani +86 more
core +1 more source
Sudden valproate-induced hyperammonemia managed with L-carnitine in a medically healthy bipolar patient: Essential review of the literature and case report [PDF]
, 2017 Valproic Acid is a commonly used psychiatric drug primarily used as a mood stabilizer. Mild hyperammonemia is a Valproic Acid common adverse effect.
Ballabio, Matteo +5 more
core +1 more source
Protective Effect of Epicatechin on Survival of PC12 Neurons Exposed to Valproic Acid [PDF]
Journal of Mazandaran University of Medical Sciences, 2023 Background and purpose: It is well established that valproic acid (VPA) is teratogenic associated with oxidative stress in humans and in all animal species tested.
Mohammad Shokrzadeh +4 more
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