High Blood Ammonia Levels Associated with Long-term Valproic Acids Therapy in Epileptic Children
MCBS (Molecular and Cellular Biomedical Sciences), 2020 Background: Valproic acid is an effective drug for controlling seizure in children with epilepsy and it is usually used for treatment as long as two years or more.
I Gusti Lanang Sidiartha +3 more
doaj +1 more source
Epilepsia, EarlyView.Abstract Objective Long‐term memory deficits are often seen in patients with temporal lobe epilepsy (TLE). Recently, studies showed that patients with hippocampal sclerosis (HS) type 2, which presents with severe neuron loss in CA1 only, performed within the normal range. However, up to 30% of HS type 2 cases have memory deficits.
Henrique Cruz +10 more
wiley +1 more source
Rapid recovery after intrathecal dexamethasone in FIRES
Epileptic Disorders, EarlyView.
João Filipe Nico +8 more
wiley +1 more source
KCNJ4 variants disrupt inward‐rectifier potassium channel function and cause refractory epilepsy
Epilepsia, EarlyView.Abstract Objective Epilepsy is a common neurological disorder with a strong genetic basis, most frequently arising from ion channel dysfunction. Although multiple inwardly rectifying potassium (Kir) channels have been implicated in epileptogenesis, the contribution of KCNJ4, which encodes the Kir2.3 channel, has not previously been established in human
Hu Pan +20 more
wiley +1 more source
Anti-tumor effects of valproic acid and 1, 25 dihydroxy vitamin D3 on HL-60 cancer cells
یافتههای نوین در علوم زیستی, 2018 11, 25 dihydroxy vitamin D3, an active metabolite of vitaminD3 has been reported to inhibit the growth of number neoplasms such as prostate, breast, colorectal, leukemia and skin cancers.
Maryam Rihimi
doaj
Lennox–Gastaut syndrome in a patient with biallelic TELO2 variants
Epileptic Disorders, EarlyView.
Melissa Odabassian, Kenneth A. Myers
wiley +1 more source
Did the French pregnancy pictogram change antiseizure medication use during pregnancy?
Epilepsia, EarlyView.Abstract Objective The aim of this study was to assess the impact of introducing a pregnancy pictogram on medication packaging on the prescription and dispensation of antiseizure medications and on the maternal and neonatal outcomes for women exposed to these medications.
Mélanie Araujo +7 more
wiley +1 more source
Effect of valproic acid on Expression of Bim gene and viability of ovarian cancer cell line A2780
مجله دانشگاه علوم پزشکی گرگان, 2017 Background and Objective: Ovarian cancer is the fifth common cancer among women and the number of new cases is increasing. Valproic acid is a histone deacetylase inhibitor effectively used to treat epilepsy and bipolar disease.
Z Amini-Farsani +3 more
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Soticlestat as an adjunctive therapy in children and young adults with Dravet syndrome
Epilepsia, EarlyView.Overview of the phase 3 trial evaluating soticlestat as adjunctive therapy in children and young adults with Dravet syndrome. Abstract Objective This study evaluated the efficacy, safety, and tolerability of soticlestat as adjunctive therapy in children and young adults with Dravet syndrome (DS).
Joseph Sullivan +14 more
wiley +1 more source
Effect of valproic acid and radiotherapy on viability of MCF-7 breast cancer cell line
مجله دانشگاه علوم پزشکی گرگان, 2014 Background and Objective: Valproic acid is used in the epilepsy, bipolar and migraine therapy. As a histone deacetylase inhibitor, Valproic acid has been recently under investigation in cancer treatment, either alone or in combination with either ...
Aghagolzade Haji H +4 more
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