Results 61 to 70 of about 5,054,451 (380)
Neurological Research and Practice, 2022 Background In the treatment of status epilepticus less is known about the influence of comorbidities on the safety profile of anticonvulsive drugs. Especially patients with diabetes mellitus may be predisposed to certain adverse events that have been ...
Annekatrin Müller +5 more
doaj +1 more source
The effects of carboxylic acids on the aqueous dispersion and electrophoretic deposition of ZrO2 [PDF]
Journal of the European Ceramic Society, Volume 32, Issue 1, 2012,
Pages 235-244, 2013 The agglomeration, electrokinetic properties and electrophoretic deposition behaviour of aqueous suspensions of ZrO2 with carboxylic acid additives were studied in comparison with conventional pH adjustment. It was found that citric acid imparted negative zeta-potential values and electrosteric stabilisation to particles in suspensions at all pH levels.
arxiv +1 more source
Advanced Healthcare Materials, EarlyView.Highly sprouting organoid‐like neurovascular spheroids (NVUs) are developed, featuring cell‐loaded poly‐3‐hydroxybutyrate 4‐hydroxybutyrate(P34HB) porous microsphere cores embedded within Gelatin Methacryloyl. NVUs formed complex vascular plexuses and secreted extracellular matrix in vitro, simulating autologous nerves and blood interaction.
Junjin Jie +5 more
wiley +1 more source
Evaluation of Antitumor Activity of Valproic Acid on K562 cells: In Vitro [PDF]
Journal of Advanced Biomedical Sciences, 2016 Backgrond & Objective: This study was performed to evaluate the antitumor effects of valproic acid (VPA) drug on K562 cells in vitro. Material & Methods: For this purpose, K562 cells were cultured and treated with different doses of valproic acid, and ...
Shahin Aalaei Diman +2 more
doaj +2 more sources
The Protective Role of Folic Acid and Vitamin E Against Toxical Effects of Valproic Acid on Liver Tissue During Period of Gestation [PDF]
, 2004 Valproic acid is an anticonvulsan drug used in epilepsy. Thehistopathological changes of valproic acid on liver and the protective effectof vitamin E and also folic acid were observed. 24 adult female Wistar Albinorats were used.
Ayşe Yıldırım +2 more
core
Clinical Chemistry, 1988 Abstract Valproic acid (VPA) is widely used as an anticonvulsant, but therapy with the drug has been associated with hepatotoxicity, either reversible hepatic dysfunction or irreversible hepatic failure. Both clinical and experimental studies have revealed several VPA-related biochemical abnormalities in the liver: inhibition of the beta-
D Cotariu, J L Zaidman
openaire +2 more sources
Emerging Therapeutic Strategies for Hearing Loss
Advanced Therapeutics, EarlyView.Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han +9 more
wiley +1 more source
Induction of chronic migraine phenotypes in a rat model after environmental irritant exposure [PDF]
, 2017 Air pollution is linked to increased emergency department visits for headache and migraine patients frequently cite chemicals or odors as headache triggers, but the association between air pollutants and headache is not well understood.
Hurley, Joyce Harts +4 more
core +1 more source
Valproic Acid: Second Generation [PDF]
Neurotherapeutics, 2007 The manuscript focuses on structure-activity relationship studies of CNS-active compounds derived from valproic acid (VPA) that have the potential to become second-generation VPA drugs. Valproic acid is one of the four most widely prescribed antiepileptic drugs (AEDs) and is effective (and regularly approved) in migraine prophylaxis and in the ...
Meir Bialer, Boris Yagen
openaire +3 more sources
Nature's Starships. I. Observed Abundances and Relative Frequencies of Amino Acids in Meteorites [PDF]
, 2014 The class of meteorites called carbonaceous chondrites are examples of material from the solar system which have been relatively unchanged from the time of their initial formation. These meteorites have been classified according to the temperatures and physical conditions of their parent planetesimals.
arxiv +1 more source