Results 91 to 100 of about 12,353,923 (294)
Konsument 3.0 – specyfika i implikacje dla marketingu w świetle opinii menedżerów
The primary objectives of the paper are to identify how managers interpret the meaning of consumer 3.0 and why they see it as an opportunity or threat to the market position of the company.
Agnieszka Wilczak
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Research software: Computer code for simulating value co-creation
A set of computer code for modelling, simulating and analysing value co-creation under different ...
Huang, D., Li, Shuliang
core
Meeting of the minds: research priorities for value co-creation in dialogical conferences
Purpose: This paper aims to explain the development of the dialogical conference, develop a framework for understanding the social construction of the dialogical conference and provide research priorities for further developing the practice in the ...
Davey, J +3 more
core +1 more source
Customer Value-Based Pricing Mechanisms:
In market transactions that are based on exchange value, it is difficult for firms to directly obtain compensation as an outcome of their involvement in value creation in the lifeworld of consumers. This limitation represents a key challenge in realizing
Junya Miyoshi
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Creating value: value co-creation and value destruction
Historically, value has been understood largely in economic terms centred on, for example, notions of price, cost, profits and shareholder wealth. However, contemporary understandings of value also point at value being created through and around products and, above all, services, experiences and relationships involved in creating good, or improving the
Stokes, Peter +3 more
openaire +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source

