Results 101 to 110 of about 1,861,130 (304)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Cultural value perception in the memorable tourism experience [PDF]
, 2013 Tourism management curriculum, if its ultimate objective is to give an introduction to the modern trends in tourism management and marketing and to prepare future destination managers, must inevitably incorporate – together with all their theoretical and
Horvath, Zsuzsanna
core +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The Strategic Impact of Corporate Responsibility and Criminal Networks on Value Co-Creation [PDF]
, 2011 This article is motivated by the increasing concern about the ever-declining security of pharmaceutical products due to the abundance of counterfeit network actors.
Frederick Ahen, Peter Zettinig
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
THE FINANCIAL PERFORMANCE OF FARMING CO-OPERATIVES: ECONOMIC VALUE ADDED VS TRADITIONAL MEASURES [PDF]
The profitability measures have limitations for examining wealth creation. Economic Value Added (EVA) is being used by businesses to measure wealth creation.
Geyser, J.M., Hall, John H.
core +1 more source
Value-in-exchange or value-in-use? Empirical insights into consumer perceptions. [PDF]
, 2012 This paper considers consumer perceptions of value against the background of emerging paradigm shifts in marketing moving away from traditional transactional ‘value-in-exchange’ approaches where marketers create value for consumers, towards a concept of ‘
Kearns, PJ, Skinner, H
core
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source