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HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Hyperpersonal Value Co-Creation in Online Communities: A Conceptual Framework [PDF]
Abedin, B, Chew, EK
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Academy of Management Proceedings, 2018
Focusing on service provider-beneficiary dyads and inter-dyad interactions in service ecosystems, we combine generativity and service-dominant logic perspectives into a model of ecosystem value co-...
Erkko Autio, Llewellyn D W Thomas
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Focusing on service provider-beneficiary dyads and inter-dyad interactions in service ecosystems, we combine generativity and service-dominant logic perspectives into a model of ecosystem value co-...
Erkko Autio, Llewellyn D W Thomas
openaire +1 more source
2021
Well-being is of vital importance for individuals as well as society at large. UNs Sustainability Goal #17, ‘Partnership for the Goals', support co-creation and co-production as necessary approaches to reach public values such as citizenship, social justice, and well-being. However, co-creation and co-production is not enough.
Dina von Heimburg +2 more
openaire +1 more source
Well-being is of vital importance for individuals as well as society at large. UNs Sustainability Goal #17, ‘Partnership for the Goals', support co-creation and co-production as necessary approaches to reach public values such as citizenship, social justice, and well-being. However, co-creation and co-production is not enough.
Dina von Heimburg +2 more
openaire +1 more source
2017
Co-creation of services in tourism industry is accorded in this work as a shared-responsibility by the service providers, local communities, and tourists who interact and collaborate to co-produce improved service offerings for a valuable experience. The process of creating improved services involves a state of harmony and balance within and among the ...
Jesus Alcoba +3 more
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Co-creation of services in tourism industry is accorded in this work as a shared-responsibility by the service providers, local communities, and tourists who interact and collaborate to co-produce improved service offerings for a valuable experience. The process of creating improved services involves a state of harmony and balance within and among the ...
Jesus Alcoba +3 more
openaire +1 more source
2017
Societal demands and consumer patterns have changed: there is a need of elaborating on new concepts and mindsets in understanding stakeholder engagement in relation to Corporate Social Responsibility (CSR) in a way that can challenge the traditional ways of thinking and provide a basis for benefits to all stakeholders.
Michael T. Devereux +1 more
openaire +1 more source
Societal demands and consumer patterns have changed: there is a need of elaborating on new concepts and mindsets in understanding stakeholder engagement in relation to Corporate Social Responsibility (CSR) in a way that can challenge the traditional ways of thinking and provide a basis for benefits to all stakeholders.
Michael T. Devereux +1 more
openaire +1 more source
The mechanisms of value co-creation
Journal of Strategic Marketing, 2012Facilitated by a wide array of technological advancements, interaction between customers and companies is taking new forms and shapes that go beyond traditional exchange. Companies are no longer perceived as sole goods providers, nor customers regarded merely as sources of money.
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Entrepreneurship as Value Co-Creation
Academy of Management Proceedings, 2017In this paper, we explore the emerging phenomenon of nascent entrepreneurs opting for a strategy of sustainability and mutual benefit as the foundation of their new venture.
Ashwin Goutham Gopi +1 more
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Online Community Value Co-creation
Online Information Review, 2020PurposeMany companies strengthen their interaction with consumers by establishing online communities and bring convenience to value co-creation with consumers. Some companies use economic and social strategies to stimulate consumer value creation. However, the way to increase the effectiveness of such corporate strategies remains unclear.
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