Results 91 to 100 of about 5,028,257 (308)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Value of Value based Education!

ISTORIA : Jurnal Pendidikan dan Ilmu Sejarah, 2022
The paper in question  aims to study the meaning of the oft quoted and over exploited term ‘Value- based Education’ . The other aim of this appear is to   understand how value -based education can bring a dramatic transformation in the life of an individual and how at the same time it can introduce  constructive changes in society.
openaire   +1 more source

AN ANALYSIS OF MORAL VALUES IN CHILDREN'S ANIMATED MOVIE "THE LITTLE PRINCE" BY MARK OSBORNE FOR EDUCATION [PDF]

Movie is one of the branches of literary works that many enthusiasts still exist. Movies in the current era are experiencing significant development, starting from the genre, the technology used, the storyline, the values contained therein, etc. Not only
Putri, Adinda Netanya Julia
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Is physical education relevant? Interpersonal skills, values and hybridity [PDF]

, 2005
Discussion surrounding the relevance of the document Health and Physical Education in the New Zealand Curriculum has focused on a range of areas. While some writers claim it has the potential to be emancipatory and the inclusion of interpersonal skills ...
Fitzpatrick, Katie, Pope, Clive C.
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Ahlâki Bir Değer Olarak Özür Dileme ve Özür Etiği

Cumhuriyet İlahiyat Dergisi, 2019
Bu çalışma, toplumsal ilişkilerde bireylerin birbirlerine karşı işlemiş olduğu kusurların telafi edilmesi ve bozulan ilişkilerin düzeltilmesinde özür dilemenin ahlâki bir değer olarak anlam ve önemine işaret etmektedir.
Mustafa Mücahi̇t
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Design and validation of a questionnaire on the perception of cheating in traditional sporting games: CHEAT-1

Frontiers in Psychology
IntroductionCheating in traditional sporting games (TSG) presents a significant challenge for values education and harmonious school coexistence. Despite its educational relevance, no validated instruments are currently available to assess students ...
Unai Sáez de Ocáriz, Pere Lavega-Burgués, Miguel Pic   +2 more
doaj   +1 more source

Does education engender cultural values that matter for economic growth? [PDF]

Empirical research has shown that cultural values matter for economic growth and has specifically identified the achievement motivation as an aspect of culture that engenders economic growth. If specific cultural values engender economic growth, how then
Afaf H. Rahim, Precious Zikhali, Prosper F. Bangwayo-Skeete   +2 more
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