Results 31 to 40 of about 31,284 (205)
Calcineurin/NFAT signaling represses genes Vamp1 and Vamp2 via PMCA-dependent mechanism during dopamine secretion by Pheochromocytoma cells. [PDF]
PLoS ONE, 2014 BACKGROUND:Plasma membrane Ca(2+)-ATPases (PMCA) extrude Ca(2+) ions out of the cell and contribute to generation of calcium oscillations. Calcium signaling is crucial for transcriptional regulation of dopamine secretion by neuroendocrine PC12 cells. Low
Michalina Kosiorek +3 more
doaj +1 more source
Virtual Integration Platforms (VIP) –A Concept for Integrated and Interdisciplinary Air Transportation Research and Assessment [PDF]
, 2011 The paper descibes a new methodology for a holistic development of air transportation concepts. The Virtual Integration Plattform (VIP) concept is based on an IT tool chain as well as human collaborative methods to deal with complex systems.
Gollnick, Volker +3 more
core +1 more source
Alzheimer’s Research & Therapy, 2021 Background There is an urgent need for objective markers of Alzheimer’s disease (AD)-related cognitive impairment in people with Down syndrome (DS) to improve diagnosis, monitor disease progression, and assess response to disease-modifying therapies ...
Alberto Lleó +21 more
doaj +1 more source
Biomolecules, 2023 Clinical data implicate fluctuations of high levels of plasma glucose in cardiovascular diseases. Endothelial cells (EC) are the first cells of the vessel wall exposed to them.
Laura Toma +5 more
doaj +1 more source
Kernel methods for detecting coherent structures in dynamical data
, 2019 We illustrate relationships between classical kernel-based dimensionality reduction techniques and eigendecompositions of empirical estimates of reproducing kernel Hilbert space (RKHS) operators associated with dynamical systems.
Husic, Brooke E. +3 more
core +1 more source
Vertebrate Anatomy, Morphology, Palaeontology, 2022 We describe a new species of capybara from late Pleistocene deposits (Rancholabrean NALMA) in northern San Diego County, California, USA which tentatively dates to Marine Isotope Stage (MIS) 5 interglacial (~130 ka to 80 ka).
Richard White +3 more
doaj +1 more source
The SNARE Protein Syntaxin 3 Confers Specificity for Polarized Axonal Trafficking in Neurons. [PDF]
, 2016 Cell polarity and precise subcellular protein localization are pivotal to neuronal function. The SNARE machinery underlies intracellular membrane fusion events, but its role in neuronal polarity and selective protein targeting remain unclear.
Albertolle, Mary E +7 more
core +1 more source
Shock Pulse Shaping in a Small-Form Factor Velocity Amplifier
Shock and Vibration, 2010 This theme of this paper is the design and characterisation of a velocity amplifier (VAMP) machine for high-acceleration shock testing of micro-scale devices.
Gerard Kelly +3 more
doaj +1 more source
Uncoupling the functions of CALM in VAMP sorting and clathrin-coated pit formation.
PLoS ONE, 2013 CALM (clathrin assembly lymphoid myeloid leukemia protein) is a cargo-selective adaptor for the post-Golgi R-SNAREs VAMPs 2, 3, and 8, and it also regulates the size of clathrin-coated pits and vesicles at the plasma membrane.
Daniela A Sahlender +4 more
doaj +1 more source
Approximate Message Passing for Underdetermined Audio Source Separation [PDF]
, 2017 Approximate message passing (AMP) algorithms have shown great promise in sparse signal reconstruction due to their low computational requirements and fast convergence to an exact solution.
Iqbal, Turab, Wang, Wenwu
core +2 more sources