Results 31 to 40 of about 9,702 (280)

Uncoupling the functions of CALM in VAMP sorting and clathrin-coated pit formation.

PLoS ONE, 2013
CALM (clathrin assembly lymphoid myeloid leukemia protein) is a cargo-selective adaptor for the post-Golgi R-SNAREs VAMPs 2, 3, and 8, and it also regulates the size of clathrin-coated pits and vesicles at the plasma membrane.
Daniela A Sahlender, Patrycja Kozik, Sharon E Miller, Andrew A Peden, Margaret S Robinson   +4 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

A New Record of Capybara (Rodentia: Caviidae: Hydrochoerinae) from the Pleistocene of San Diego County, California with Remarks on Their Biogeography and Dispersal in the Pleistocene of Western North America

Vertebrate Anatomy, Morphology, Palaeontology, 2022
We describe a new species of capybara from late Pleistocene deposits (Rancholabrean NALMA) in northern San Diego County, California, USA which tentatively dates to Marine Isotope Stage (MIS) 5 interglacial (~130 ka to 80 ka).
Richard White, Jim Mead, Gary Morgan, Thomas A. Deméré   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Mechanochemical and surgical ablation of an anomalous upper extremity marginal vein in CLOVES syndrome identifies PIK3CA as the culprit gene mutation

Journal of Vascular Surgery Cases and Innovative Techniques, 2020
Anomalous marginal veins of the trunk or extremities are congenitally incompetent entities found in association with phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA)-related overgrowth syndromes, such as Klippel-Trénaunay ...
Young Lim, PhD, Arash Fereydooni, MD, MS, Anand Brahmandam, MD, Alan Dardik, MD, PhD, Keith Choate, MD, PhD, Naiem Nassiri, MD   +5 more
doaj   +1 more source

Advances in Chitosan Nanoparticles: A Comprehensive Review of Properties, Synthesis, Characterization, Multidisciplinary Applications, and Future Perspectives

Journal of Applied Polymer Science, EarlyView.
This review highlights the synthesis of chitosan nanoparticles from natural sources, the thorough characterization of them, and use of microscopic and spectroscopic methods. It emphasizes that it has some indispensable properties such as being non‐toxic, antimicrobial, and capable of controlled drug release.
Mariam Sohail Mansoor, Nayab Raza, Furqana Bibi, Madiha Mumtaz, Asif Abbas, Farasat Haider, Basit Ali   +6 more
wiley   +1 more source

FOOTWEAR DIVERSIFICATION BY TYPIFICATION OF COMPONENT PARTS [PDF]

Annals of the University of Oradea: Fascicle of Textiles, Leatherwork, 2018
Diversification of a footwear product, constructively designed in a basic model, can be assured by putting into practice several diversification criteria.
HARNAGEA Marta Catalina, SECAN Cristina
doaj  

Problematic putative pachycephalosaurids: Synchrotron µCT imaging shines new light on the anatomy and taxonomic validity of Gravitholus albertae from the Belly River Group (Campanian) of Alberta, Canada

Vertebrate Anatomy, Morphology, Palaeontology, 2023
The taxonomic validity of the holotype and sole specimen of the pachycephalosaurid Gravitholus albertae (TMP 1972.027.0001) from the Belly River Group (Alberta, Canada), remains unresolved forty years after its first description.
Aaron Dyer, Mark Powers, Phiip Currie
doaj   +1 more source

Show Me the Brain!!: A modern approach to neuroanatomy education

Anatomical Sciences Education, EarlyView.
Abstract Show Me the Brain!! (SMtB) is a digital system for interactive graphics that is designed to support instruction in neuroanatomy and neuroscience. It will soon be made open‐source and freely available. SMtB bridges medical and traditional neuroanatomy instruction with the computational systems and representational conventions common in ...
Nicholas C. Hindy, Anthony J. Bishara, Ellie Lovellette, John R. Pani   +3 more
wiley   +1 more source

vamp n

, 1988
vamp nV is for vamps/ That keep your feet cosy/ On long winter nights/ When you feel a bit dozy.PRINTED ITEM DNE SupG.M. Story FEB. 27 1988 WK[Add to DNE vamp n 1, to 1977 cite]Used I and SupUsed I and SupNot usedCard is stamped DNE Sup but is not ...

core   +4 more sources