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Enterococcal vanB resistance locus in anaerobic bacteria in human faeces
Lancet, The, 2001While developing a rapid method to detect carriers of vancomycin-resistant enterococci (VRE), we found the vanB gene by PCR in 13 of 50 human faecal specimens that did not contain culturable VRE. Passaging under antibiotic selection allowed us to isolate two species of anaerobic bacteria that were vanB PCR positive, vancomycin resistant, and ...
John Davies +2 more
exaly +3 more sources
Diagnostic Microbiology and Infectious Disease, 2020
Especially in immunocompromised and intensive care patients VRE sepsis is associated with high mortality. The GeneXpert vanA/vanB assay is marketed for fast molecular surveillance of VRE colonization in peri-anal and rectal swabs. The aim of this study was to evaluate this assay for its usefulness for rapid identification of the vanAB determinant from ...
A, Both +6 more
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Especially in immunocompromised and intensive care patients VRE sepsis is associated with high mortality. The GeneXpert vanA/vanB assay is marketed for fast molecular surveillance of VRE colonization in peri-anal and rectal swabs. The aim of this study was to evaluate this assay for its usefulness for rapid identification of the vanAB determinant from ...
A, Both +6 more
openaire +2 more sources
Therapeutic Options for Infections Due to vanB Genotype Vancomycin-Resistant Enterococci
Microbial Drug Resistance, 2021Enterococci are ubiquitous, facultative, anaerobic Gram-positive bacteria that mainly reside, as part of the normal microbiota, in the gastrointestinal tracts of several animal species, including humans. These bacteria have the capability to turn from a normal gut commensal organism to an invasive pathogen in patients debilitated ...
Riccardi, Niccolò +6 more
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Plasmid-Mediated vanB Glycopeptide Resistance in Enterococci
Microbial Drug Resistance, 1995ABSTRACT Enterococcus faecium , which was highly resistant to vancomycin (MIC 256 mg/liter), but susceptible to teicoplanin (MIC 2 mg/liter), caused two distinct episodes of infection on a renal unit in the United Kingdom.
N, Woodford +6 more
openaire +2 more sources
Lactoferrin-induced reduction of vanB vancomycin resistance in enterococci
International Journal of Antimicrobial Agents, 2001The mucosal protein lactoferrin (LF) reduces the MIC of vancomycin for staphylococcal isolates sensitive to this glycopeptide. The purpose of this research was to investigate the effect of LF on the MIC of vancomycin for vanB resistant isolates of Enterococcus faecalis (Efs1) and E. faecium (Efm1).
E C, Leitch, M D, Willcox
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Real-time PCR for the rapid detection of vanA and vanB genes
Diagnostic Microbiology and Infectious Disease, 2003A real-time PCR assay suitable for use on the Roche LightCycler platform was developed to replace an existing gel-based PCR assay for the simultaneous detection of the vanA & vanB genes in enterococcal isolates. Novel Fluorescence Resonance Energy Transfer (FRET) hybridization probes were designed. The multiplex real-time PCR assay and the existing gel-
Silvano, Palladino +4 more
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No regional spread of vancomycin-resistant enterococci with vanA or vanB in Kitakyushu, Japan
Journal of Infection and Chemotherapy, 2004Outbreaks of vancomycin-resistant enterococci (VRE) infection occur sporadically in Japan, and their frequency has been gradually increasing. We experienced a nosocomial outbreak of VRE in two hospitals in the city of Kitakyushu, and the spread of VRE strains was suspected in this area.
Tetsuro Muratani
exaly +3 more sources
Identification of a new gene, vanV, in vanB operons of Enterococcus faecalis
International Journal of Antimicrobial Agents, 2011Subinhibitory concentrations of vancomycin are known to induce a cell-wall stimulon in some Gram-positive pathogens, but this has never been studied in the genus Enterococcus. In this study, Enterococcus faecalis V583 strain was submitted to a subinhibitory concentration of vancomycin.
Tânia, Ribeiro +4 more
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