Results 21 to 30 of about 320,119 (385)

Differential Activity of the Combination of Vancomycin and Amikacin on Planktonic vs. Biofilm-Growing Staphylococcus aureus Bacteria in a Hollow Fiber Infection Model [PDF]

, 2018
Combining currently available antibiotics to optimize their use is a promising strategy to reduce treatment failures against biofilm-associated infections. Nevertheless, most assays of such combinations have been performed in vitro on planktonic bacteria
Adamis, Aeschlimann, Backo, Brown, Butterfield, Cadwell, Cargill, Cokça, Conlon, Davies, Deresinski, Donlan, Doroshenko, Drusano, Ekdahl, Ferro, Frimodt-Møller, Gumbo, Gálvez, Hanrahan, Hogan, Ivanova, Jung, Kato, Knudsen, Lamp, LaPlante, LaPlante, Lebeaux, Lebeaux, Lenhard, Lewis, Liu, Mandell, Matzke, McConoughey, Moore, Nicasio, Nielsen, Patel, Post, Rodloff, Rybak, Singh, Singh, Song, Srinivasan, Toutain, Toutain, Toutain, Waineo, Watanakunakorn, Wu, Yanagisawa, Yuan, Zelenitsky, Álvarez   +56 more
core   +3 more sources

Prediction of Unbound Vancomycin Levels in Intensive Care Unit and Nonintensive Care Unit Patients: Total Bilirubin May Play an Important Role

Infection and Drug Resistance, 2021
Xiao Li,1,* Wen Xu,1,* Ran Li,2 Qie Guo,1 Xiangpeng Li,1 Jialin Sun,1 Shuhong Sun,1 Jing Li1 1Department of Clinical Pharmacy, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, 266003, People’s Republic of China; 2Department of ...
Li X, Xu W, Li R, Guo Q, Li X, Sun J, Sun S, Li J   +7 more
doaj  

Evaluation of a vancomycin dosing nomogram in obese patients weighing at least 100 kilograms.

Pharmacy Practice, 2018
Background: There remains variability in both practice and evidence related to optimal initial empiric dosing strategies for vancomycin. Objective: Our primary objective was to describe the percentage of obese patients receiving vancomycin doses ...
Bowers RD, Cooper AA, Wente CL, Wilson DT, Johnson SW, Drew RH.   +5 more
doaj   +1 more source

The Surgical Infection Society revised guidelines on the management of intra-abdominal infection [PDF]

, 2017
Background: Previous evidence-based guidelines on the management of intra-abdominal infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and 2010. At the time the most recent guideline was released, the plan was to update
Chang, Phillip K, Diaz, Jose J, Jr, Huston, Jared M, May, Addison K, Mazuski, John E, Mollen, Kevin P, Nadler, Evan P, O\u27Neill, Patrick J, Prince, Jose M, Rosengart, Matthew R, Sawyer, Robert G, Tessier, Jeffrey M   +11 more
core   +3 more sources

Halophiles and Their Biomolecules: Recent Advances and Future Applications in Biomedicine [PDF]

, 2020
The organisms thriving under extreme conditions better than any other organism living on Earth, fascinate by their hostile growing parameters, physiological features, and their production of valuable bioactive metabolites.
Amoozegar, Mohammad Ali, Corral Villa, Paulina, Ventosa Ucero, Antonio   +2 more
core   +1 more source

Lack of synergistic nephrotoxicity between vancomycin and piperacillin/tazobactam in a rat model and a confirmatory cellular model.

Journal of Antimicrobial Chemotherapy, 2020
BACKGROUND Vancomycin and piperacillin/tazobactam are reported in clinical studies to increase acute kidney injury (AKI). However, no clinical study has demonstrated synergistic toxicity, only that serum creatinine increases.
Gwendolyn M. Pais, Jiajun Liu, Sean N. Avedissian, Danielle Hiner, T. Xanthos, A. Chalkias, E. d’Aloja, E. Locci, A. Gilchrist, W. Prozialeck, N. Rhodes, T. Lodise, J. Fitzgerald, K. Downes, A. Zuppa, M. Scheetz   +15 more
semanticscholar   +1 more source

Oral vancomycin desensitisation to treat Clostridium difficile infection in a vancomycin allergic patient

World Allergy Organization Journal, 2013
The prevalence of Clostridium difficile infection (CDI) is increasing worldwide. Oral vancomycin is an effective and frequently used treatment. However, patients with CDI who are allergic to intravenous vancomycin cannot receive oral vancomycin due to ...
Shanti Mahabir, Ren Yik Lim, Fidelma Fitzpatrick, Colm Magee, Mary Keogan   +4 more
doaj   +1 more source

The continued value of disk diffusion for assessing antimicrobial susceptibility in clinical laboratories: Report from the Clinical and Laboratory Standards Institute Methods Development and Standardization Working Group [PDF]

, 2018
Expedited pathways to antimicrobial agent approval by the U.S. Food and Drug Administration (FDA) have led to increased delays between drug approval and the availability of FDA-cleared antimicrobial susceptibility testing (AST) devices.
Burnham, Carey-Ann D, Ferrell, Andrea, Hsiung, Andre, Humphries, Romney M, Kircher, Susan, Krause, Kevin M, Malherbe, Rianna   +6 more
core   +2 more sources

Clinical Application Value of Pharmacokinetic Parameters of Vancomycin in Children Treated in the Pediatric Intensive Care Unit

Frontiers in Pediatrics, 2022
ObjectiveTo explore the efficacy and safety of vancomycin as measured by pharmacokinetic/pharmacodynamic parameters in children with severe infection in the Pediatric Intensive Care Unit (PICU) and to determine the appropriate threshold for avoiding ...
Bo Zhou, Bo Zhou, Bo Zhou, Bo Zhou, Wenyi Xiong, Ke Bai, Ke Bai, Ke Bai, Ke Bai, Hongxing Dang, Hongxing Dang, Hongxing Dang, Hongxing Dang, Jing Li, Jing Li, Jing Li, Jing Li, Feng Xu, Feng Xu, Feng Xu, Feng Xu, Yue-qiang Fu, Yue-qiang Fu, Yue-qiang Fu, Yue-qiang Fu, Chengjun Liu, Chengjun Liu, Chengjun Liu, Chengjun Liu   +28 more
doaj   +1 more source

Airborne Multidrug-Resistant Bacteria Isolated from a Concentrated Swine Feeding Operation [PDF]

, 2004
The use of nontherapeutic levels of antibiotics in swine production can select for antibiotic resistance in commensal and pathogenic bacteria in swine. As a result, retail pork products, as well as surface and groundwaters contaminated with swine waste ...
Amy Chapin, Ana Rule, Jensen LB, Kellogg Schwab, Kristen Gibson, Mackiewicz B, Timothy Buckley, Zahn JA   +7 more
core   +2 more sources