Design and synthesis of modified peptide antibiotics of the vancomycin family [PDF]
, 2008 The ability of bacteria to constantly evolve new methods of resistance to antibacterial therapies represents a constant challenge in medicine. Emergence of strains of enterococci and S. Aureus that show resistance to vancomycin is an alarming phenomenon,
Bone, Philip Andrew
core +7 more sources
Role of membrane vesicles in the transmission of vancomycin resistance in Enterococcus faecium. [PDF]
Sci RepClonal transmission and horizontal gene transfer (HGT) contribute to the spread of vancomycin-resistant enterococci (VRE) in global healthcare. Our study investigated vesiduction, a HGT mechanism via membrane vesicles (MVs), for vanA and vanB genes that ...
Lehmkuhl J +5 more
europepmc +2 more sources
Vancomycin Resistance in Enterococcus and Staphylococcus aureus. [PDF]
Microorganisms, 2022 Enterococcus faecalis, Enterococcus faecium and Staphylococcus aureus are both common commensals and major opportunistic human pathogens. In recent decades, these bacteria have acquired broad resistance to several major classes of antibiotics, including ...
Li G, Walker MJ, De Oliveira DMP.
europepmc +2 more sources
Methicillin resistance Staphylococcus aureus (MRSA) and Vancomycin Resistant Staphylococcus aureus (VRSA) problem in human and livestock and solutions. [PDF]
Basrah Journal of Veterinary Research, 2023 Staphylococcus aureus is an opportunistic bacterium of humans and other mammals that is becoming more clinically and veterinary important due to its fast development of antibiotic resistance. Some of these S. aureus varieties are methicillin-resistant S.
Marwan Mohammed +2 more
doaj +1 more source
Genetic Mechanisms of Vancomycin Resistance in Clostridioides difficile: A Systematic Review. [PDF]
Antibiotics (Basel), 2022 Antimicrobial resistance to treatments for Clostridioides difficile infection (CDI) poses a significant threat to global health. C. difficile is widely thought to be susceptible to oral vancomycin, which is increasingly the mainstay of CDI treatment ...
Eubank TA +3 more
europepmc +2 more sources
Comparative genomics of vancomycin-resistant Staphylococcus aureus strains and their positions within the clade most commonly associated with methicillin-resistant S. aureus hospital-acquired infection in the United States [PDF]
, 2012 This research was supported in part with federal funds from the NIAID/NIH/DHHS, including the Harvard-wide Program on Antibiotic Resistance (NIH grant AI083214), NIH grant EY017381 (M.S.G.), contract HHSN27220090018C, and the NARSA program supported ...
Griggs, Allison +34 more
core +1 more source
Cost-effectiveness analysis of fidaxomicin versus vancomycin in Clostridium difficile infection [PDF]
, 2014 OBJECTIVES: Fidaxomicin was non-inferior to vancomycin with respect to clinical cure rates in the treatment of Clostridium difficile infections (CDIs) in two Phase III trials, but was associated with significantly fewer recurrences than vancomycin.
Cornely, Oliver A. +5 more
core +1 more source
Absence of High-Level Vancomycin Resistance in Enterococci Isolated from Meat-Processing Facilities
Emerging Infectious Diseases, 2001 Enterococci isolated from packaging areas of meat-processing facilities that produce ready-to-eat meat products were examined for high-level vancomycin resistance.
Peter W. Bodnaruk +2 more
doaj +1 more source
mSystemsStaphylococcus aureus is a major source of community and nosocomial infections. Due to the extensive application of antibiotics, S. aureus has developed resistance to antibiotics, especially vancomycin, making clinical treatment challenging ...
Yujie Li +9 more
doaj +1 more source
A Phenotypically Silent
mSphere, 2016 In the last decade, Clostridium difficile infection (CDI) has reached an epidemic state with increasing incidence and severity in both health care and community settings.
Daniel R. Knight +4 more
doaj +1 more source