VapCs of Mycobacterium tuberculosis cleave RNAs essential for translation [PDF]
, 2016 The major human pathogen Mycobacterium tuberculosis can survive in the host organism for decades without causing symptoms. A large cohort of Toxin–Antitoxin (TA) modules contribute to this persistence.
Gerdes, Kenn +3 more
core +1 more source
RASTA-Bacteria: a web-based tool for identifying toxin-antitoxin loci in prokaryotes [PDF]
, 2007 RASTA-Bacteria is an automated method that allows quick and reliable identification of toxin/antitoxin loci in sequenced prokaryotic genomes, whether they are annotated Open Reading Frames or ...
Barloy-Hubler, Frédérique +1 more
core +4 more sources
BMC Genomics, 2019 Background Mycobacterium pinnipedii, a member of the Mycobacterium tuberculosis Complex (MTBC), is capable of infecting several host species, including humans.
Taiana T. Silva-Pereira +7 more
doaj +1 more source
Mechanism of RNA cleavage by VapC from Pyrobaculum aerophilum [PDF]
, 2012 Proteins belonging to the PIN-domain family are widespread across bacteria, archaea and eukaryotes. PIN-domain structures are well characterised and contain three highly conserved acidic residues that are orientated to form the active site of the enzyme.
Duyvestyn, Johanna Maria
core
Wake Me When It\u27s Over- Bacterial Toxin-Antitoxin Proteins and Induced Dormancy [PDF]
, 2016 Toxin-antitoxin systems are encoded by bacteria and archaea to enable an immediate response to environmental stresses, including antibiotics and the host immune response.
Coussens, Nathan P., Daines, Dayle A.
core +2 more sources
Networking in microbes: conjugative elements and plasmids in the genus Alteromonas [PDF]
, 2017 Background To develop evolutionary models for the free living bacterium Alteromonas the genome sequences of isolates of the genus have been extensively analyzed.
Francisco Rodriguez-Valera +2 more
core +3 more sources
Toxin–Antitoxin Modules: Genetic Elements with Many Faces and Functions
BacteriaToxin–antitoxin (TA) modules represent sophisticated regulatory networks that have evolved from simple plasmid maintenance factors into multifunctional genetic modules orchestrating bacterial stress responses, pathogenesis, and ecological adaptation ...
Aayush Bahl +5 more
doaj +1 more source
The VapBC Toxin-Antitoxin systems : regulators of the nitrogen-fixing symbiosis Rhizobium-Legume
, 2020 Lors de la symbiose fixatrice d’azote entre la légumineuse modèle Medicago truncatula et la rhizobiacée Sinorhizobium meliloti, les bactéries, différenciées en bactéroïdes dans la nodosité, réduisent l’azote atmosphérique (N2) en ammoniac (NH3), directement assimilable par la plante.
openaire +1 more source
Nucleotide sequences of 16 transmissible plasmids identified in nine multidrug-resistant Escherichia coli isolates expressing an ESBL phenotype isolated from food-producing animals and healthy humans [PDF]
, 2017 Objectives Nine extended-spectrum β-lactamase (ESBL)-producing Escherichia coli isolated from healthy humans and food-producing animals were found to transfer their cefotaxime resistance marker at high frequency in laboratory conjugation experiments. The
Fanning, Séamus +5 more
core
The Biology and Biochemistry of PhoH2 proteins [PDF]
, 2013 PhoH2 proteins are found in a diverse range of organisms. To date little is known about these proteins and the role they play in the organisms in which they reside.
Andrews, Emma Sophie Vout
core +1 more source