Results 71 to 80 of about 721 (155)
살모넬라균 유래 VapBC 와 SehAB 독소-항독소 단백질의 구조적, 기능적 연구 [PDF]
, 2020 학위논문(박사)--서울대학교 대학원 :약학대학 약학과,2020. 2. 이봉진.세균성의 독소-항독소 시스템은 영양부족, 항생제 처리, 산화스트레스 등의 세포가 힘든 환경에 처했을 때 세포의 유지에 필수적인 역할을 하는 것으로 알려져 주목받고 있다. 독소-항독소 시스템은 항독소의 독소 저해 방식 혹은 항독소의 형태에 따라 6가지 독소-항독소 시스템이 존재한다. 그 중에서 타입 2 독소-항독소 시스템은 가장 많이 연구가 진행되었다.
박동원
core
The Biochemistry of VapBC Toxin-Antitoxins
, 2011 The VapBC toxin-antitoxin (TA) systems were first identified in 2005 and little is known about their contemporary biological function, despite the fact that VapBC TAs are the largest TA family and are widespread in bacteria and archaea (Arcus, Rainey ...
McKenzie, Joanna Leigh
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Characterisation of VapBC Toxin-Antitoxins from Mycobacterium tuberculosis
, 2013 Toxin-antitoxin (TA) systems were identified more than 20 years ago on the mini F plasmid of Escherichia coli as plasmid stability elements; components responsible for purging bacterial cells that lack the plasmid from the population.
Sharrock, Abigail Victoria
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PLoS Genetics, 2009 Toxin-antitoxin (TA) systems, stress-responsive genetic elements ubiquitous in microbial genomes, are unusually abundant in the major human pathogen Mycobacterium tuberculosis. Why M.
Holly R Ramage +2 more
doaj +1 more source
The Biology and Biochemistry of PhoH2 proteins
, 2013 PhoH2 proteins are found in a diverse range of organisms. To date little is known about these proteins and the role they play in the organisms in which they reside.
Andrews, Emma Sophie Vout
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Investigation of possible tolerance mutations in a VapBC toxin–antitoxin system through structure determination [PDF]
Acta Crystallographica Section A Foundations and Advances, 2021 Maria Raadkjær Nielsen +1 more
openaire +1 more source
Plasticity and maintenance of the virulence plasmid in Shigella flexneri and Shigella sonnei
, 2021 Shigella is the major cause of human bacillary dysentery worldwide. Shigella flexneri and Shigella sonnei account for >90% of shigellosis globally, and evolved from commensal Escherichia coli following acquisition of a large plasmid, pINV.
Pilla, Giulia
core +1 more source
BMC Genomics, 2019 Background Mycobacterium pinnipedii, a member of the Mycobacterium tuberculosis Complex (MTBC), is capable of infecting several host species, including humans.
Taiana T. Silva-Pereira +7 more
doaj +1 more source
Time to Diagnosis and Persistence: The Two Major Determinants of Effective Tuberculosis Control
, 2015 The greatest challenge confronting effective tuberculosis (TB) eradication is the time to diagnosis, and duration of treatment of chronically infected individuals which represent a pool of infection.
Ruthe, Alaine Tess
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DNase I protection of the vapBC-1 locus control region by Fis and Vap proteins.
, 2013 (A) The 32P-labeled sense strand of 153 bp DNA substrate containing vapB-1 TIR and upstream sequence in the vapBC-1 locus control region, is shown with numbers indicating the distance from the 5′-labeled end.
Sehresh Saleem (329519) +2 more
core +1 more source