Results 61 to 70 of about 724 (156)
Genetic plasticity of the Shigella virulence plasmid is mediated by intra- and inter-molecular events between insertion sequences. [PDF]
PLoS Genetics, 2017 Acquisition of a single copy, large virulence plasmid, pINV, led to the emergence of Shigella spp. from Escherichia coli. The plasmid encodes a Type III secretion system (T3SS) on a 30 kb pathogenicity island (PAI), and is maintained in a bacterial ...
Giulia Pilla +2 more
doaj +1 more source
The Biochemistry of VapBC Toxin-Antitoxins [PDF]
, 2011 The VapBC toxin-antitoxin (TA) systems were first identified in 2005 and little is known about their contemporary biological function, despite the fact that VapBC TAs are the largest TA family and are widespread in bacteria and archaea (Arcus, Rainey ...
McKenzie, Joanna Leigh
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Characterisation of VapBC Toxin-Antitoxins from Mycobacterium tuberculosis [PDF]
, 2013 Toxin-antitoxin (TA) systems were identified more than 20 years ago on the mini F plasmid of Escherichia coli as plasmid stability elements; components responsible for purging bacterial cells that lack the plasmid from the population.
Sharrock, Abigail Victoria
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Toxins VapC and PasB from Prokaryotic TA Modules Remain Active in Mammalian Cancer Cells
Toxins, 2014 Among the great number of addictive modules which have been discovered, only a few have been characterized. However, research concerning the adoption of toxins from these systems shows their great potential as a tool for molecular biology and medicine.
Łukasz Wieteska +3 more
doaj +1 more source
The ntrPR Operon of Sinorhizobium meliloti Is Organized and Functions as a Toxin-Antitoxin Module
Molecular Plant-Microbe Interactions, 2006 The chromosomal ntrPR operon of Sinorhizobium meliloti encodes a protein pair that forms a toxin-antitoxin (TA) module, the first characterized functional TA system in Rhizobiaceae. Similarly to other bacterial TA systems, the toxin gene ntrR is preceded
Monica Bodogai +5 more
doaj +1 more source
The Journal of biological chemistry, 2009 In prokaryotes, cognate toxin-antitoxin pairs have long been known, but no three-dimensional structure has been available for any given complex from Mycobacterium tuberculosis. Here we report the crystal structure and activity of a member of the VapBC family of complexes from M. tuberculosis.
Linda, Miallau +6 more
openaire +1 more source
PLoS ONE, 2013 Mobilome of hyperthermophilic archaea dwelling in deep-sea hydrothermal vents is poorly characterized. To gain insight into genetic diversity and dynamics of mobile genetic elements in these environments we have sequenced five new plasmids from different
Mart Krupovic +4 more
doaj +1 more source
The Biology and Biochemistry of PhoH2 proteins [PDF]
, 2013 PhoH2 proteins are found in a diverse range of organisms. To date little is known about these proteins and the role they play in the organisms in which they reside.
Andrews, Emma Sophie Vout
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Plasticity and maintenance of the virulence plasmid in Shigella flexneri and Shigella sonnei [PDF]
, 2021 Shigella is the major cause of human bacillary dysentery worldwide. Shigella flexneri and Shigella sonnei account for >90% of shigellosis globally, and evolved from commensal Escherichia coli following acquisition of a large plasmid, pINV.
Pilla, Giulia
core +1 more source
Time to Diagnosis and Persistence: The Two Major Determinants of Effective Tuberculosis Control [PDF]
, 2015 The greatest challenge confronting effective tuberculosis (TB) eradication is the time to diagnosis, and duration of treatment of chronically infected individuals which represent a pool of infection.
Ruthe, Alaine Tess
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