Results 81 to 90 of about 721 (155)
, 2020 TA (toxin-antitoxin) loci are ubiquitous in prokaryotic micro-organisms, including archaea, yet their physiological function is largely unknown. For example, preliminary reports have suggested that TA loci are microbial stress-response elements, although
Sabrina Tachdjian +4 more
core
, 2022 Sistemi toksin-antitoksin (TA) so sestavljeni iz dveh komponent. Toksin je praviloma stabilen protein, ki v celicah, kjer se izraža, deluje citostatično ali citotoksično, antitoksin pa je nestabilen protein ali RNA, ki preprečuje delovanje toksina in ...
Imperl, Jernej
core
Structure and Proposed Activity of a Member of the VapBC Family of Toxin-Antitoxin Systems [PDF]
Journal of Biological Chemistry, 2009 Linda Miallau +6 more
openaire +1 more source
Toxin–Antitoxin Modules: Genetic Elements with Many Faces and Functions
BacteriaToxin–antitoxin (TA) modules represent sophisticated regulatory networks that have evolved from simple plasmid maintenance factors into multifunctional genetic modules orchestrating bacterial stress responses, pathogenesis, and ecological adaptation ...
Aayush Bahl +5 more
doaj +1 more source
, 2009 A leptospirose é uma zoonose mundial causada por bactéria do gênero Leptospira. O desenvolvimento de uma vacina de subunidade eficaz seria de grande interesse em saúde pública.
Luana Melo Lopes, Lopes, Luana Melo
core +1 more source
, 2011 Forty seven of the toxin-antitoxin modules in the genome of Mycobacterium tuberculosis belong to the VapBC family in which the VapC toxin is a member of the PIN-domain protein family associated with nuclease activity.
Ahidjo, Bintou Ahmadou
core
, 2018 The effect of conditionally expressing VapC29, VapBC29 or empty vector (EV) on growth (a) and cell viability (b) was examined in a wild-type and vapBC knockout strain of M. smegmatis mc2155.
Joanna L. Hicks (5706827) +4 more
core +1 more source
, 2020 During the nitrogen-fixing symbiosis between the model legume Medicago truncatula and the rhizobiaceae Sinorhizobium meliloti, bacteria, differentiated into bacteroids within the nodule, reduce atmospheric nitrogen (N2) into ammonia (NH3), directly ...
Syska, Camille
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Characterization of PIN-domain Toxin-antitoxins VapBC from Mycobacterium tuberculosis
, 2015 Thesis (Ph.D.)--University of Rochester. School of Medicine & Dentistry. Dept. of Biochemistry and Biophysics, 2015.Bacterial toxin-antitoxin systems play important roles in plasmid inheritance, cellular adaptation to stress, the formation of persister ...
Butler, J. Scott, Jin, Guangze
core
Five Mtb VapC proteins display the same sequence specificity against 924 Pentaprobe RNA.
, 2018 The ribonuclease activity of VapC1, 19, 27, 29 & 39 (2.9 μM) was tested against the 924 pentaprobe RNA (18 μM). Negative controls included no VapC (RNA only) at the beginning (RNA only 0) and end (RNA only 60) of the assay reaction, addition of EDTA, and
Joanna L. Hicks (5706827) +4 more
core +1 more source