Results 91 to 100 of about 721 (155)

The VapBC Toxin–Antitoxin System Enhances Shigella flexneri Fitness Through Coordination of Metabolic Stress Adaptation and Virulence

Abstract Shigella flexneri is a facultative intracellular pathogen that causes bacillary dysentery by invading and replicating within intestinal epithelial cells. Successful intracellular survival requires the bacterium to balance metabolic adaptation with the sustained expression of virulence ...
Saifi, Estelle, Ageron, Elisabeth, Egger, Keith, Reisacher, Caroline, Frapy, Eric, Lamberioux, Morgan, Payne, Shelley, Enninga, Jost, Arbibe, Laurence   +8 more
openaire   +1 more source

Functional Genomics of Stress Response in the Hyperthermophilic Crenarchaeon Sufolobus solfataricus and Role of vapBC Toxin-Antitoxin Loci in RNA Management.

, 2008
Functional genomics tools were used to examine the dynamic stress response of the hyperthermophile Sulfolobus solfataricus subjected to thermal and pH shifts relative to growth under normal conditions.
Tachdjian, Sabrina
core  

Competition binding of 50TIR and 50US by Vap proteins.

, 2013
Gel shift products from addition of 50US substrate into samples containing 50TIR substrate and either (A) VapBC-1 or (B) VapC-1 at a 150∶1 molar ratio of VapC-1 protein to DNA. VapB-1 and VapC-1 are at a 3∶1 molar ratio in the VapBC-1 samples, but VapC-1∶
Sehresh Saleem (329519), Dayle A. Daines (329520), Susan D. Cline (329518)   +2 more
core   +1 more source

VapC-1 of nontypeable Haemophilus influenzae is a ribonuclease [PDF]

, 2007
Nontypeable Haemophilus influenzae (NTHi) organisms are obligate parasites of the human upper respiratory tract that can exist as commensals or pathogens.
Wu, Mack H, Yuan, Sarah Y, Daines, Dayle A   +2 more
core  

A Tale about Shigella: Evolution, Plasmid, and Virulence. [PDF]

Microorganisms, 2023
Haidar-Ahmad N, Manigat FO, Silué N, Pontier SM, Campbell-Valois FX.   +4 more
europepmc   +1 more source

Bioinformacijska analiza lokusov vapBC cianobakterije Microcystis aeruginosa PCC 7806 in eksperimentalna karakterizacija potencialnih toksinov VapC29, VapC33 in VapC45

, 2022
Toxin-antitoxin (TA) systems are composed of two components. The toxin is typically a stable protein, which exhibits cytostatic or cytotoxic activity in the cells that express it. The antitoxin is either an unstable protein or RNA, which inhibits the activity of the toxin and therefore enables normal cell growth.
openaire   +1 more source

Maintenance of the Shigella sonnei Virulence Plasmid Is Dependent on Its Repertoire and Amino Acid Sequence of Toxin-Antitoxin Systems. [PDF]

J Bacteriol, 2022
Martyn JE, Pilla G, Hollingshead S, Winther KS, Lea S, McVicker G, Tang CM.   +6 more
europepmc   +1 more source

Virulence plasmid pINV as a genetic signature for <i>Shigella flexneri</i> phylogeny. [PDF]

Microb Genom, 2022
Pilla G, Arcari G, Tang CM, Carattoli A.
europepmc   +1 more source

Editorial for Special Issue "Molecular Research in Vaccinology and Vaccine Development". [PDF]

Curr Issues Mol Biol
Farsang A.
europepmc   +1 more source

Structural and functional characterization of VapBC52 toxin-antitoxin system from Mycobacterium tuberculosis. [PDF]

Nucleic Acids Res
Singh M, Singh C, Nair AV, Ahmad I, Sharma A, Bhasin M, Jain V, Singh R, Thakur KG.   +8 more
europepmc   +1 more source