Results 61 to 70 of about 3,797 (199)

Emerging Trends and Research Focus in Erectile Dysfunction Treatment: A 1993–2023 Bibliometric Analysis

Andrologia, Volume 2026, Issue 1, 2026.
Erectile dysfunction (ED) is a common sexual disorder worldwide significantly affects men’s quality of life. However, there remains a lack of comprehensive bibliometric analysis of ED treatment. This study aims to utilize bibliometric methods to assess the research progress in ED treatment and identify the research hot spots and emerging trends in this
Kefan Li, Wenpeng Song, Zhuo Zhou, Xiaohui Tan, Mancheng Xia, Pengchao Gao, Fangzhou Zhao, Honggang Ying, Weidong Song, Zhongcheng Xin, Yiming Yuan, Woong Jin Bae, Ruili Guan, Harleen Khatra   +13 more
wiley   +1 more source

Phosphodiesterase‐5 Inhibition and Alzheimer's Disease Risk: A Mendelian Randomisation Study

Aging Cell, Volume 24, Issue 12, December 2025.
Preclinical studies suggest PDE5 inhibitors may improve cognition, but observational evidence on Alzheimer's disease (AD) risk is mixed. We performed a cis‐Mendelian randomisation analysis across four AD genome‐wide association studies (GWAS) datasets and a sex‐stratified analysis using UK Biobank data.
Marta Alcalde‐Herraiz, Benjamin Woolf, Junqing Xie, Emma Anderson, Dipender Gill, Ioanna Tzoulaki, Laura M. Winchester, James Yarmolinsky, Daniel Prieto‐Alhambra, Danielle Newby   +9 more
wiley   +1 more source

Acute vasodilator response to vardenafil and clinical outcome in patients with pulmonary hypertension

, 2015
PURPOSE: Acute vasodilator testing is recommended in patients with pulmonary arterial hypertension to identify individuals who may benefit from long-term treatment with oral calcium channel blockers.
Wikström, Gerhard, Bondesson, Ulf,, Wernroth, Lisa, Egeröd, Hanna,, Wernroth, Lisa,, Wikström, Gerhard,, Hedeland, Mikael,, Sandqvist, Anna,, Bondesson, Ulf, Egeröd, Hanna, Schneede, Jörn,, Henrohn, Dan,, Henrohn, Dan, Hedeland, Mikael   +13 more
core   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

A Systematic Literature Review Exploring the Efficacy and Safety of Tadalafil and Sildenafil in Pulmonary Arterial Hypertension

Pulmonary Circulation, Volume 15, Issue 4, October 2025.
ABSTRACT Pulmonary Arterial Hypertension (PAH) is a rare, chronic and progressive disease affecting the heart and lungs. Endothelin receptor antagonist (ERA) + phosphodiesterase type 5 inhibitor (PDE5i) treatment is recommended for all PAH patients. The two approved PDE5is are tadalafil and sildenafil.
Rajan Saggar, Nora Rahhali, Assunta Senatore, Marinella Sandros, David Lopez, Gabriela Gomez Rendon, Ambar Khan, Ellie Boulton, Anna Bobrowska, Sandeep Sahay   +9 more
wiley   +1 more source

Erectile dysfunction in dermatology and venereology: From aetiopathogenic mechanisms to practical considerations for dermato‐venereologists

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 10, Page 1725-1737, October 2025.
Multiple inflammatory, infectious and autoimmune dermato‐venereological conditions are associated with erectile dysfunction (ED) due to underlying intricate vasculogenic, neurogenic, endocrine and psychogenic mechanisms. It is recommended that practitioners screen dermatology patients for ED and associated comorbidities, provide personalized lifestyle ...
Andrei Tanasov, George‐Sorin Tiplica
wiley   +1 more source

Incremental cost-effectiveness of various monthly doses of vardenafil

, 2011
ObjectiveTo compare the cost-effectiveness of four, six, and eight doses per month of vardenafil in the context of pharmacy benefit decision making.MethodsA Markov model was used to estimate the incremental cost-effectiveness of zero, four, six, or eight
Good, Chester B., Chester B. Good, Aspinall, Sherrie L., Cunningham, Francesca E., Smith, Kenneth J., Sherrie L. Aspinall, Kenneth J. Smith, Francesca E. Cunningham   +7 more
core   +1 more source

Integrative snRNA‐seq, molecular docking and dynamics simulations identifies Lasmiditan as drug candidate for Alzheimer's disease

Clinical and Translational Medicine, Volume 15, Issue 8, August 2025.
Multi‐cohort snRNA‐seq analysis identified 20 key transcriptional regulators in Alzheimer's disease (AD). Lasmiditan was the top drug identified for repurposing as it showed strong binding stability with ETV6 and favourable blood–brain barrier permeability.
Martin Nwadiugwu, Md Selim Reza, Boluwatife Afolabi, Demetrius M. Maraganore, Hui Shen, Hongwen Deng   +5 more
wiley   +1 more source

Efficacy and Safety of Vardenafil in Renal Transplant Recipients With Erectile Dysfunction

, 2006
PubMedID: 16797309Erectile dysfunction (ED) profoundly affects the quality of life. The prevalence of ED in renal transplant recipients is reported by high as 50% to 60%.
Balal M., Sertdemir Y., Demir E., Paydas S., Erken U.   +4 more
core   +1 more source

EYE‐CODE Protocol for the Nonophthalmologist for Treatment of Retinal Artery Occlusion After Intra‐Arterial Injection of Soft‐Tissue Fillers: 2025 Update

Journal of Cosmetic Dermatology, Volume 24, Issue 7, July 2025.
ABSTRACT Background Vision loss following a facial esthetic procedure with soft‐tissue fillers is an event for which there is only a short treatment window to restore blood flow before irreversible ischemic damage occurs. Objective To provide a current standardized treatment approach for the management of retinal artery occlusion after intra‐arterial ...
Sheila Barbarino, Saami Khalifian, John Fezza   +2 more
wiley   +1 more source